Prevalence and associated factors of depression among diabetic outpatients attending diabetic clinic at public hospitals in Eastern Ethiopia: A cross-sectional study

Ebrahim, Mohamed G.; Tamiru, Dawit; Hawulte, Behailu; Misgana, Tadesse

doi:10.1177/20503121211066244

Cited by 8 publications

(13 citation statements)

References 58 publications

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“…All studies were institutional cross-sectional in nature. Five studies conducted in Oromia region [ 22 , 32 – 35 ], three in Addis Ababa [ 21 , 36 , 37 ], three in Amhara[ 20 , 38 , 39 ], three in SNNP[ 40 – 42 ], one in Tigrai [ 43 ] and one in Harari[ 44 ]. The sample sizes ranged from 260 to 423.…”

Section: Resultsmentioning

confidence: 99%

“…Leaving out one study at a time, the pooled estimated prevalence of depression is ranged from 32.91 (95% CI, 25.97–39.85) to 36.31 (95%, 29.78–42.84). In a leave-1-out analysis, omitting the study of Ebrahim et al [ 44 ] reduced the prevalence to 33.65% (95% CI, 26.26–41.05). Similarly, removing the study of Habtewold et al[ 21 ] lowered the prevalence of depression to 33.94%(95% CI, 26.4-41.49).…”

Section: Meta Regressionmentioning

confidence: 99%

“…To examine the association between sex and depression in diabetic patients, we reviewed all studies included in this systematic review. Being women was identified as a significant factor associated with depression in four primary studies included in this meta-analysis [ 20 , 22 , 34 , 44 ]. A total of 1637 subjects were included to analyze the association between and being women and depression.…”

Section: Meta Regressionmentioning

confidence: 99%

“…Eight primary studies with a total subject of 2883 reported limited social support as a determinant for depression in diabetic patients [ 20 – 22 , 33 , 36 , 39 , 42 , 44 ]. The pooled odds ratio showed that diabetes peoples with limited social support had a 2.37 times higher risk to experience depression as compared to diabetes having good social support (AOR = 2.37; 95% CI: 1.68–3.34), I 2 = 58.8%, P = 0.017) (Table 4 ).…”

Section: Meta Regressionmentioning

confidence: 99%

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Depression and determinants among diabetes mellitus patients in Ethiopia, a systematic review and meta-analysis

2023

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Introduction Primary studies have estimated the prevalence of depression and its determinants among diabetes patients. However, studies synthesizing this primary evidence are limited. Hence, this systematic review aimed to determine the prevalence of depression and identify determinants of depression among diabetes in Ethiopia. Methods This systematic review and meta-analysis included a search of PubMed, Google Scholar, Scopus, Science Direct, PsycINFO, and Cochrane library. Data were extracted using Microsoft Excel and analyzed using STATA statistical software (v. 14). Data were pooled using a random-effects model. Forest plots, and Egger’s regression test were all used to check for publication bias. Heterogeneity (I)2 was computed. Subgroup analysis was done by region, publication year, and depression screening instrument. In addition, the pooled odds ratio for determinants was calculated. Results Sixteen studies, including 5808 participants were analyzed. The prevalence of depression in diabetes was estimated to be 34.61% (95% CI: 27.31–41.91). According to subgroup analysis by study region, publication year, and screening instrument, the highest prevalence was observed in Addis Ababa (41.98%), studies published before 2020 (37.91%), and studies that used Hospital Anxiety and Depression Scale (HADS-D) (42.42%,) respectively. Older age > 50 years (AOR = 2.96; 95% CI: 1.71–5.11), being women (AOR = 2.31; 95% CI: 1.57, 3.4), longer duration with diabetes (above 5 years) (AOR = 1.98; 95% CI: 1.03–3.8), and limited social support (AOR = 2.37; 95% CI: 1.68–3.34), were the determinants of depression in diabetic patients. Conclusion The results of this study suggest that the prevalence of depression in diabetes is substantial. This result underscores the importance of paying particular attention to prevent depression among diabetes. Being older, not attending formal education, longer duration with diabetes, having comorbidity, and low adherence to diabetes management were all associated. These variables may help clinicians identify patients at high risk of depression. Future studies focusing on the causal association between depression and diabetes are highly recommended.

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Section: Resultsmentioning

confidence: 99%

Section: Meta Regressionmentioning

confidence: 99%

Section: Meta Regressionmentioning

confidence: 99%

Section: Meta Regressionmentioning

confidence: 99%

See 2 more Smart Citations

Depression and determinants among diabetes mellitus patients in Ethiopia, a systematic review and meta-analysis

2023

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“…Sample size was calculated using a single population proportion formula by considering the P value from the prevalence of depression in T2DM patients in Harar, Eastern Ethiopia: 48.9% (24). 95% con dence level, 5% margin of error, and estimated total T2DM population during the study period were (N) = 712.…”

Section: Sample Size Determination and Sampling Techniquementioning

confidence: 99%

Depression and Glycemic Control among Adult Type 2 Diabetic Patients: A Crossectional Study in a Comprehensive Specialized Hospital, Jigjiga, Ethiopia

Yimam

Seid

Hassen

et al. 2023

Preprint

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Background Globally, there is an alarming rise in type 2 diabetes mellitus prevalence, with the highest rate of increment observed in developing countries, including Ethiopia. The disease has a multifaceted impact, ranging from physical and mental symptoms to socioeconomic consequences. While most of these burdens have due consideration, the mental health impact of diseases such as depression is often unnoticed, undiagnosed, or untreated. More importantly, depression is known to have a higher likelihood of occurrence in patients with type 2 diabetes mellitus. Hence, the present study aimed to assess the prevalence of depression and its sociodemographic predictors, clinical predictors, and glycemic control among adult type 2 diabetic patients at Sheik Hassan Yabare Comprehensive Specialized Hospital, Jigjiga, Ethiopia. Methods A hospital-based cross-sectional study was conducted using a systematic random sampling method from October 3 to November 13, 2022. The Patient Health Questionnaire was used to assess depression, while glycemic control was measured using glycated hemoglobin (HgA1c). The data was entered into Epidata version 4.6 for data entry and then exported to SPSS version 26 for analysis. Multiple logistic regressions with the backward elimination method were performed, and a p-value of < 0.05 with a 95% confidence interval was taken as statistically significant. Results A total of 263 participants were included, with a response rate of 94.6%. Of the respondents, 134 (51%) were male, making up more than half of the total. The overall prevalence of depression was 47.1% (95% CI: 41.1–53.2). Depression was further classified, as follows, based on its severity: the majority of 66 (25.1%) had mild depression, followed by 44 (16.7%) with moderate depression, 9 (3.4%) with moderately severe depression, and 5 (1.9%) with severe depression. A multivariable logistic regression analysis indicated that poor glycemic control (AOR = 1.93; 95% CI = 1.05, 3.53), DM complications (AOR = 2.02; 95% CI = 1.09, 3.74), and DM duration of 5–10 years since diagnosis (AOR = 2.29; 95% CI = 1.21, 4.34) were independently associated with depression. Conclusions Our study revealed a significant burden of depression among type 2 diabetes mellitus patients receiving follow-up care at the hospital. Glycemic control, the presence of complications, and longer duration of diabetes were identified as predictors of depression. Therefore, concerned stakeholders should work to improve blood sugar control and promote healthy behavior, particularly among those with complications or who have been sick for an extended period of time.

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Psychosocial and clinical factors associated with depression among diabetic patients in Amhara region comprehensive specialized hospitals, Ethiopia, 2022; a multicenter prevalence study

Belew,

Getu,

Getahun

et al. 2024

Health Science Reports

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BackgroundDepression commonly coexists with diabetes leads to complications and worsens the outcome. Even though the problem affects low‐ and middle‐income countries including Ethiopia, only a few studies have been done to show the magnitude of the problem and factors associated with it. So, the study was conducted to fill those gapsObjectiveThe main objective of this study was to assess psychosocial and clinical factors associated with depression among diabetic patients in Amhara region comprehensive specialized hospitals, Ethiopia, 2022.MethodsA hospital‐based cross‐sectional study was conducted in randomly selected hospitals of Amhara region from January 7 to February 10, 2022. A total of 426 diabetic patients who were on outpatient follow‐up were selected using a multistage sampling technique. A p‐value of ≤0.25 in the bivariable analysis was used to select variables for the multivariable analysis. A p‐value < 0.05 within a 95% confidence interval was considered to be significantly associated factors.ResultOut of 426 interviewed diabetes patients 203 (47.7%) had depression. Moderate physical activity (AOR = 0.50, 95% CI (0.29, 0.86)). low medication adherence (AOR = 2.10, 95% CI (1.22, 3.62)), medium medication adherence (AOR = 1.78, 95% CI (1.04, 3.06)), and high social support (AOR = 0.54, 95% CI (0.33, 0.91)) were significantly associated with depression among diabetic patients.ConclusionThe overall prevalence of depression among diabetic patients was higher than in other developing countries. Hence, special attention to preventing depression and maintaining mental illness among patients with chronic illnesses, especially diabetes should be given.

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Prevalence and associated factors of depression among diabetic outpatients attending diabetic clinic at public hospitals in Eastern Ethiopia: A cross-sectional study

Cited by 8 publications

References 58 publications

Depression and determinants among diabetes mellitus patients in Ethiopia, a systematic review and meta-analysis

Depression and determinants among diabetes mellitus patients in Ethiopia, a systematic review and meta-analysis

Depression and Glycemic Control among Adult Type 2 Diabetic Patients: A Crossectional Study in a Comprehensive Specialized Hospital, Jigjiga, Ethiopia

Psychosocial and clinical factors associated with depression among diabetic patients in Amhara region comprehensive specialized hospitals, Ethiopia, 2022; a multicenter prevalence study

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