Prevalence and associated factors with peripheral neuropathies in the general population in the rural area of Adjohoun in Benin

Gnonlonfoun, Dieudonné; Sowanou, Arlos; Gnigone, Pupchen; Gbessemehlan, Antoine; Mapaga, Jennifer Nyangui; Aballo, Wilson; Choki, Blaise; Magné, Julien; Boumédiène, Farid; Preux, Pierre‐Marie; Houinato, Dismand Stéphan

doi:10.1016/j.jocn.2023.01.008

Cited by 3 publications

(1 citation statement)

References 27 publications

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“…In contrast, a crosssectional study by Gnonlonfoun et al in the Republic of Benin found the prevalence of peripheral neuropathy as low as 16.9%, but the study was conducted among the general population, unlike the present study carried out among persons with diabetes. 25 Contrary to expectations, it was observed that the prevalence of microvascular complications, especially peripheral neuropathy, decreases with an increase in age (within the aging participants), such that the highest prevalence occurred in the 60-69 age group and the lowest prevalence was recorded in those participants aged 80 years and above. One reason for this observation may be the higher number of participants in the 60-69 age group than other groups in the study, hence the higher prevalence.…”

Section: Discussioncontrasting

confidence: 67%

Prevalence, pattern, and potential predictors of microvascular complications in aging Nigerians with type 2 diabetes

Balogun,

Emuze,

Adebusoye

et al. 2024

Geriatr Care

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In low-resource settings like Nigeria, the rising prevalence of diabetes is accompanied by an excessive burden of microvascular complications from diabetes. This study aimed to determine the prevalence and predictors of microvascular complications among older patients with diabetes mellitus. Therefore, a 2-year retrospective cross-sectional study was carried out among elderly diabetes patients at the Chief Tony Anenih Geriatric Center outpatient diabetes clinic. A total of 148 diabetic patients were included in the study; the mean (± standard deviation) age was 70.89 (±6.99) years, with 71.6% of the studied population being female. Logistic regression analysis was employed to determine the prevalence and predictors of microvascular complications. Results show that the prevalence of microvascular complications in older diabetes patients was 73.9% [95% confidence interval (CI)=66.7-81.6] with peripheral neuropathy (77.1% prevalence, 95% CI=67.9-84.8) being the most common and retinopathy being the least prevalent (95% CI=4.7-16.8). The significant predictors of developing microvascular complications were intake of oral agents only [p=0.013, odds ratio (OR)=2.35, 95% CI=1.15-16.81], number of comorbidities (p=0.041, adjusted OR=5.28, 95% CI=1.09-27.93) and systolic blood pressure (p=0.042, OR=1.02, 95% CI=1.00-1.04). Considering the high prevalence of microvascular complications among aging patients with diabetes mellitus, older patients should comply with oral medications and undergo regular check-ups, and more advocacy should be undertaken to strengthen geriatric healthcare systems to mitigate comorbidities and reduce complications.

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Section: Discussioncontrasting

confidence: 67%

Prevalence, pattern, and potential predictors of microvascular complications in aging Nigerians with type 2 diabetes

Balogun,

Emuze,

Adebusoye

et al. 2024

Geriatr Care

View full text Add to dashboard Cite

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Knowledge, attitudes and practices of general practitioners on peripheral neuropathies in Benin in 2021

Gnonlonfoun,

Sowanou,

Gnigone

et al. 2024

International Journal of Neuroscience

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Pattern, causes and functional outcome of peripheral neuropathies in the Amazon region

Deschamps,

Nacher,

Preux

et al. 2024

PLoS ONE

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Background Peripheral neuropathies have a wide variety of causes and pathophysiologies. Assuming that there are local particularities in the Amazon region, the aim of this study was to describe the characteristics of patients by determining the factors associated with functional severity. Methods This was a retrospective observational study at Cayenne Hospital between January 2015 and May 2023. We included patients from the French hospital activity monitoring database “Programme de médicalisation des systèmes d’information” by searching for the keywords "neuropathy" "Guillain-Barre syndrome"(GBS) "multineuritis" "polyneuritis". The Peripheral Neuropathy Disability (PND) score was determined to quantify the functional severity of patients. Results A total of 754 patients were included, with a mean age of 60 years (SD = 14.6) and a predominance of women (53.6%). Gait disorders were present in 16.3% of patients (PND between 2 and 4). Mortality was 14.3% at 3 years. The most common causes of neuropathy were diabetes (58.2%), chemotherapy induced polyneuropathy toxicity (21.5%), Guillain-Barre syndrome (6.0%), unlabeled (3.2%), and infectious causes (2.0%). Infectious causes mainly included HIV in 13 patients (43.3%) and leprosy in 8 patients (26.7%). Only GBS was significantly associated with functional severity but all patients with a deficiency had a severe score. But, after excluding GBS, infectious causes were significantly associated with a severe PND score (aOR = 3.69 [1.18–11.58]). Discussion The characteristics of French Guiana combine those found in developed and developing countries, with an over-representation of infections (notably HIV and leprosy), and diabetes. The causes often result from social inequalities in health. Conclusion This is the first comprehensive study of the diverse causes of neuropathy in a territory undergoing epidemiologic transition in the Amazon region.

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Prevalence and associated factors with peripheral neuropathies in the general population in the rural area of Adjohoun in Benin

Cited by 3 publications

References 27 publications

Prevalence, pattern, and potential predictors of microvascular complications in aging Nigerians with type 2 diabetes

Prevalence, pattern, and potential predictors of microvascular complications in aging Nigerians with type 2 diabetes

Knowledge, attitudes and practices of general practitioners on peripheral neuropathies in Benin in 2021

Pattern, causes and functional outcome of peripheral neuropathies in the Amazon region

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