Prevalence and associated risk factors for work disability in <scp>E</scp>gyptian patients with ankylosing spondylitis from one center

Abdul-Sattar, Amal; Magd, Sahar Abou El

doi:10.1111/1756-185x.12306

Cited by 5 publications

(7 citation statements)

References 29 publications

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“…The initial search yielded 1391 citations, from which 21 studies were identified for inclusion after screening [6,35,46,[49][50][51][52][53][54][55][56][57][58][59][60][61][62][63][64][65][66] (Fig. 1).…”

Section: Study Selection Characteristics and Quality Assessmentmentioning

confidence: 99%

“…The majority (six of nine) of studies that evaluated economic burden of delayed diagnosis assessed work disability or employment; in all of these studies, longer diagnosis delay was associated with a greater likelihood of work disability or unemployment [46,52,56,58,62,66] (Table 4). In the three studies that evaluated treatment costs and healthcare utilization, longer diagnosis delay was associated with higher costs related to doctors' visits and specialist services [35,57], unnecessary spinal surgery [35], and treatments [57,66] (Table 4).…”

Section: Economic Burden Of Delayed Diagnosismentioning

confidence: 99%

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Clinical, Economic, and Humanistic Burden Associated With Delayed Diagnosis of Axial Spondyloarthritis: A Systematic Review

Ahuja

Rajput

et al. 2020

Rheumatol Ther

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Introduction: Few studies have evaluated the impact of delayed diagnosis of axial spondyloarthritis (axSpA) on the overall burden of disease. The objective of this review was to evaluate the available literature on the clinical, economic, and humanistic burden of delayed diagnosis in patients with axSpA. Methods: This systematic literature review was conducted and reported according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. We searched the MEDLINE and Embase databases for Englishlanguage publications of original research articles (up to July 12, 2018) and conference abstracts (January 1, 2014, to July 12, 2018) reporting studies of adult patients with delayed diagnosis of axSpA associated with clinical,

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Section: Study Selection Characteristics and Quality Assessmentmentioning

confidence: 99%

Section: Economic Burden Of Delayed Diagnosismentioning

confidence: 99%

Clinical, Economic, and Humanistic Burden Associated With Delayed Diagnosis of Axial Spondyloarthritis: A Systematic Review

Ahuja

Rajput

et al. 2020

Rheumatol Ther

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“…The bulk of studies showed that the prevalence of work disability is high in these patients and is associated with both clinical and psychosocial factors. 13,14 Specifically, labour-intensive jobs and manual professions were associated with poorer work outcomes. 13,15 Ulus et al compared ankylosing spondylitis patients with healthy controls and found that functional impairment assessed by BASFI was a significant predictor of work instability scores.…”

Section: Discussionmentioning

confidence: 99%

Navigating the Factors Affecting Functional Impairment in Spondyloarthritis

Maatallah,

Cherif,

Ferjani

et al. 2024

Sultan Qaboos Univ Med J

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Objectives: To assess the predictive factors of functional impairment in SpA patients assessed with BASFI (Bath Ankylosing Spondylitis Functional Index) and LI (Lequesne Index). Methods: We conducted a retrospective study that included SpA patients. Socio-demographics and disease-related data were reported (data collection spread over four months from August 2019 to November 2019). Disease activity was assessed using the Bath Ankylosing Spondylitis-Global score (BASG-s) and the Bath Ankylosing Spondylitis disease activity Index (BASDAI). The spinal mobility was evaluated by The Bath Ankylosing Spondylitis Metrology Index (BASMI). Structural progression was evaluated with The Bath Ankylosing Spondylitis Radiologic Index (BASRI) and modified Stoke ankylosing spondylitis spine score (mSASSS). We conducted a multivariate analysis to search for predictive factors associated with BASFI and LI. Significance was accepted for a p < 0.05 for all statistical tests. Results: Two hundred and sixty-three patients were included. Mean age of the patients was 38.9 ±12.7 years, sex-ratio=2.7. Mean age of onset of SpA was 27.6 ± 10.8. Disease duration was 11.3 ±9.5 years. Occupation was significantly associated with BASFI score and LI. A significant functional impact was significantly correlated with a long duration of the disease. The two scores were correlated with a limitation of spinal mobility (BASMI), a greater disease activity (BASDAI and ESR) and a greater impact of the disease on health status (BASG-s). Significant functional impairment was also correlated with structural impairment: mSASSS, BASRI and sacroiliitis grade. The variables independently related to BASFI were the mSASSS score and the BASDAI. The variables independently related to LI were the profession (unemployed subjects had higher scores), mSASSS score, and the BASMI. Conclusion: Occupation, disease activity, mobility and structural progression predicted functional impairment in Tunisian SpA patients. Keywords: Spondyloarthritis; North Africa; Function; Impairment.

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“… 74 Work disability was greater in SpA patients with delayed diagnosis when compared with early diagnosis. 70 , 72 , 83 , 98 , 99 In a retrospective study on Health Search Database in Italy, 1084 patients were identified with a delay in diagnosis of three years. During this delay, approximately €153,000 were spent on services related to specialist visits and drugs not related to SpA.…”

Section: Discussionmentioning

confidence: 99%

“…Different factors were associated with disability, including delayed diagnosis, lower educational level, manual work, rural living, peripheral arthritis manifestation, and psychological factors. 99 To date, there are no published studies from Saudi Arabia that assessed the HRCU costs of SpA and the impact of the delayed diagnosis on costs.…”

Section: Discussionmentioning

confidence: 99%

The Impact of Spondyloarthritis on Health-Related Quality of Life and Healthcare Resource Utilization in Saudi Arabia: A Narrative Review and Directions for Future Research

Al Rayes,

Salah,

Hamad

et al. 2023

OARRR

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Spondylarthritis (SpA) is an umbrella term that encompasses a wide range of rheumatological disorders. Several studies demonstrated that SpA is associated with increased healthcare resource utilization (HCRU) and a lower health-related quality of life (HRQoL). This review aimed to summarize the current literature regarding the multidimensional impact of SpA on HRQoL and HCRU in Saudi Arabia and explore the correlation of the extent of severity of SpA with HRQoL and HCRU. Although the prevalence of SpA varies across different populations and is correlated with HLA-B27 prevalence, the magnitude of SpA in the Saudi population has not been extensively evaluated. Few studies have investigated the impact of SpA on HRQoL and HCRU in Saudi Arabia and the Middle East. There is a need to study the cost-effectiveness of various SpA treatment strategies, including biologic disease-modifying anti-rheumatic drugs (bDMARDs), to prioritize healthcare spending in the Saudi healthcare system. Data on SpA in Saudi Arabia and the Middle East region are mainly based on expert views, with few population-based studies compared to other regions. Therefore, there is an imperative need to develop high-quality, national-level epidemiological studies that assess the following: (1) more accurate estimates of the current prevalence of SpA in Saudi Arabia, including the prevalence of axial SpA and psoriatic arthritis; (2) the phenotypes/clinical characteristics of SpA, including disease severity and extra-articular involvement; (3) the impact of SpA on the HRQoL of the patients and the factors that can predict the extent of impaired HRQoL in such population, which can represent the first step in developing psychological interventions that should be personalized to this patient population; (4) the impact of implementing formal assessment of disease activity on the management of the patients and, subsequently, their HRQoL; and (5) the HCRU and costs for patients with SpA, and how treatment patterns can affect this cost.

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Prevalence and associated risk factors for work disability in Egyptian patients with ankylosing spondylitis from one center

Abstract: The prevalence of WD among Egyptian patients with AS is considerably high. Clinical and psychosocial factors, in particular, appear to be associated with WD and should therefore be prioritized in clinical practice.

Cited by 5 publications

References 29 publications

Clinical, Economic, and Humanistic Burden Associated With Delayed Diagnosis of Axial Spondyloarthritis: A Systematic Review

Clinical, Economic, and Humanistic Burden Associated With Delayed Diagnosis of Axial Spondyloarthritis: A Systematic Review

Navigating the Factors Affecting Functional Impairment in Spondyloarthritis

The Impact of Spondyloarthritis on Health-Related Quality of Life and Healthcare Resource Utilization in Saudi Arabia: A Narrative Review and Directions for Future Research

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