Prevalence and Characteristics of Dry Eye Disease After Cataract Surgery: A Systematic Review and Meta-Analysis

Miura, Maria; Inomata, Takenori; Nakamura, Masahiro; Sung, Jaemyoung; Nagino, Ken; Midorikawa‐Inomata, Akie; Zhu, Jun; Fujimoto, Keiichi; Okumura, Yuichi; Fujio, Kenta; Hirosawa, Kunihiko; Akasaki, Yasutsugu; Kuwahara, Mizu; Eguchi, Atsuko; Shokirova, Hurramhon; Murakami, Akira

doi:10.1007/s40123-022-00513-y

Cited by 29 publications

(18 citation statements)

References 92 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The common risk factors for developing DED include systemic disease, systemic medications, hormone replacement therapy, and previous corneal refractive surgeries. [ 7 , 8 , 16 ] History to ascertain the presence of these should be asked. Patients complaining of dryness, grittiness, burning sensation, and itching deserve a closer look as these symptoms are suggestive of DED.…”

Section: Preoperative Evaluationmentioning

confidence: 99%

“…[ 5 , 6 ] Studies have shown that approximately one-tenth to one-third of patients undergoing cataract surgery have DED postoperatively. [ 7 , 8 ] Mechanisms like corneal nerve transection, inflammation, goblet cell loss, phototoxicity from the operating microscope, preservative-induced toxicity, and worsening of meibomian gland dysfunction (MGD) are the likely contributory factors. [ 9 ] Murine models of DED have shown significant increase in inflammatory infiltrates, lymphangiogenesis, and neovascularization following cataract surgery compared to non-DED models.…”

mentioning

confidence: 99%

See 1 more Smart Citation

Management of cataract in dry eye disease: Preferred practice pattern guidelines

Donthineni

Deshmukh

Ramamurthy

et al. 2023

Indian Journal of Ophthalmology

View full text Add to dashboard Cite

Cataract surgery is one of the most commonly performed ophthalmic surgeries in the world. Dry eye disease (DED) is found to coexist in most patients with cataracts due to the overlapping age groups of both these conditions. Preoperative evaluation for DED is important to improve outcomes. A pre-existing DED affecting the tear film is likely to affect biometry. Moreover, special intraoperative considerations are needed in eyes with DED to reduce complications and improve postoperative outcomes. Dry eye disease (DED) is known to occur following an uneventful cataract surgery or a pre-existing DED is likely to worsen following cataract surgery as well. In these situations, despite a good visual outcome, patient dissatisfaction is common owing to the distressing DED symptoms. This review aims to summarize the preoperative, intraoperative, and postoperative considerations when performing cataract surgery in the presence of a coexisting DED.

show abstract

Section: Preoperative Evaluationmentioning

confidence: 99%

mentioning

confidence: 99%

Management of cataract in dry eye disease: Preferred practice pattern guidelines

Donthineni

Deshmukh

Ramamurthy

et al. 2023

Indian Journal of Ophthalmology

View full text Add to dashboard Cite

show abstract

“…Dry eye presents a wide range of subjective symptoms, including ocular dryness, eye discomfort, decreased vision, and generalized fatigue [28][29][30][31] , which demonstrates a high degree of heterogeneity in its symptomology on an individual basis. Dry eye symptoms have been reported to negatively affect one's quality of vision and work productivity, ultimately resulting in financial burden and societal economic loss [32][33][34][35][36][37][38] . However, the mainstay approach to dry eye management revolves around post-facto treatment of symptoms and suppression of further exacerbation; dry eye currently has no cure 39) .…”

Section: Symptomology Of Dry Eye and Its Stratificationmentioning

confidence: 99%

P4 Medicine for Heterogeneity of Dry Eye: A Mobile Health-based Digital Cohort Study

Inomata

Sung

Yee

et al. 2023

Juntendo Medical Journal

Self Cite

View full text Add to dashboard Cite

During the 5 th Science, Technology, and Innovation Basic Plan, the Japanese government proposed a novel societal concept -Society 5.0-that promoted a healthcare system characterized by its capability to provide unintrusive, predictive, longitudinal care through the integration of cyber and physical space. The role of Society 5.0 in managing our quality of vision will become more important in the modern digitalized and aging society, both of which are known risk factors for developing dry eye. Dry eye is the most common ocular surface disease encountered in Japan with symptoms including increased dryness, eye discomfort, and decreased visual acuity. Owing to its complexity, implementation of P4 (predictive, preventive, personalized, participatory) medicine in managing dry eye requires a comprehensive understanding of its pathology, as well as a strategy to visualize and stratify its risk factors. Using DryEyeRhythm ® , a mobile health (mHealth) smartphone software (app), we established a route to collect holistic medical big data on dry eye, such as the subjective symptoms and lifestyle data for each individual. The studies to date aided in determining the risk factors for severe dry eye, the association between major depressive disorder and dry eye exacerbation, eye drop treatment adherence, app-based stratification algorithms based on symptomology, blink detection biosensoring as a dry eye-related digital phenotype, and effectiveness of app-based dry eye diagnosis support compared to traditional methods.These results contribute to elucidating disease pathophysiology and promoting preventive and effective measures to counteract dry eye through mHealth.

show abstract

“…Additionally, DED is highly heterogeneous, with patients presenting with seemingly unpredictable combinations of the abovementioned symptoms. Therefore, patients with DED are prone to having their nonspecific presentations overlooked, and many are left undiagnosed without appropriate management [ 3 , 9 , 12 - 14 ]. There is no definitive cure for DED, and current standards of care comprise ex post facto symptom management, highlighting the importance of early diagnosis and intervention to prevent disease progression and longstanding damage [ 15 - 19 ].…”

Section: Introductionmentioning

confidence: 99%

Diagnostic Ability of a Smartphone App for Dry Eye Disease: Protocol for a Multicenter, Open-Label, Prospective, and Cross-sectional Study

Nagino¹,

Okumura²,

Yamaguchi³

et al. 2023

JMIR Res Protoc

Self Cite

View full text Add to dashboard Cite

Background Dry eye disease (DED) is one of the most common ocular surface diseases. Numerous patients with DED remain undiagnosed and inadequately treated, experiencing various subjective symptoms and a decrease in quality of life and work productivity. A mobile health smartphone app, namely, the DEA01, has been developed as a noninvasive, noncontact, and remote screening device, in the context of an ongoing paradigm shift in the health care system, to facilitate a diagnosis of DED. Objective This study aimed to evaluate the capabilities of the DEA01 smartphone app to facilitate a DED diagnosis. Methods In this multicenter, open-label, prospective, and cross-sectional study, the test method will involve using the DEA01 smartphone app to collect and evaluate DED symptoms, based on the Japanese version of the Ocular Surface Disease Index (J-OSDI), and to measure the maximum blink interval (MBI). The standard method will then involve a paper-based J-OSDI evaluation of subjective symptoms of DED and tear film breakup time (TFBUT) measurement in an in-person encounter. We will allocate 220 patients to DED and non-DED groups, based on the standard method. The primary outcome will be the sensitivity and specificity of the DED diagnosis according to the test method. Secondary outcomes will be the validity and reliability of the test method. The concordance rate, positive and negative predictive values, and the likelihood ratio between the test and standard methods will be assessed. The area under the curve of the test method will be evaluated using a receiver operating characteristic curve. The internal consistency of the app-based J-OSDI and the correlation between the app-based J-OSDI and paper-based J-OSDI will be assessed. A DED diagnosis cutoff value for the app-based MBI will be determined using a receiver operating characteristic curve. The app-based MBI will be assessed to determine a correlation between a slit lamp–based MBI and TFBUT. Adverse events and DEA01 failure data will be collected. Operability and usability will be assessed using a 5-point Likert scale questionnaire. Results Patient enrollment will start in February 2023 and end in July 2023. The findings will be analyzed in August 2023, and the results will be reported from March 2024 onward. Conclusions This study may have implications in identifying a noninvasive, noncontact route to facilitate a diagnosis of DED. The DEA01 may enable a comprehensive diagnostic evaluation within a telemedicine setting and facilitate early intervention for undiagnosed patients with DED confronting health care access barriers. Trial Registration Japan Registry of Clinical Trials jRCTs032220524; https://jrct.niph.go.jp/latest-detail/jRCTs032220524 International Registered Report Identifier (IRRID) PRR1-10.2196/45218

show abstract

Prevalence and Characteristics of Dry Eye Disease After Cataract Surgery: A Systematic Review and Meta-Analysis

Cited by 29 publications

References 92 publications

Management of cataract in dry eye disease: Preferred practice pattern guidelines

Management of cataract in dry eye disease: Preferred practice pattern guidelines

P4 Medicine for Heterogeneity of Dry Eye: A Mobile Health-based Digital Cohort Study

Diagnostic Ability of a Smartphone App for Dry Eye Disease: Protocol for a Multicenter, Open-Label, Prospective, and Cross-sectional Study

Contact Info

Product

Resources

About