Prevalence and Characteristics of Overactive Bladder in Women in a Primary Care Setting

Cheung, Wellman; Harel, Miriam; Abulafia, Ovadia; Khan, Nadia; Choi, Karmina K; Bluth, Martin H.; Vincent, M.

doi:10.1016/s0022-5347(09)61590-1

Cited by 6 publications

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“…Overactive bladder syndrome (OAB) is a common condition affecting up to 43% of women in the United States. 1,2 For many patients, symptoms of OAB include a loss of self-esteem, restriction of activities and psychological distress. 3–7 The American Urological Association and the Society of Urodynamics, Female Pelvic Medicine and Urogenital Reconstruction recommends patients try medication and behavioral modification before proceeding to third-line OAB treatments which include percutaneous tibial nerve stimulation (PTNS), onabotulinumtoxinA and sacral neuromodulation (SNM).…”

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confidence: 99%

Patient Perceptions Impact Progression to Third-Line Therapy for Treatment of Overactive Bladder

et al. 2021

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Purpose: We aimed to understand the reasons patients choose to pursue thirdline overactive bladder (OAB) therapy. Materials and Methods: We conducted a mixed methods study that included patient interviews and survey data. Eligible patients were diagnosed by symptoms, had tried behavioral modifications, and OAB medications enrolled from October 2018 to August 2019. In addition to interviews, patients completed 4 surveys: the Pelvic Floor Distress Inventory, Overactive Bladder Questionnaire Short Form, Life Orientation TestdRevised, and a patient confidence in the health care system survey. Qualitative interview data were analyzed thematically. Logistic regression and chi-square analysis was used to analyze survey data. Results: A total of 69 patients were consented, 4 withdrew, and 51 completed both interview and survey data. Overall 55% of patients were Caucasian, 45% were African American, and their average age was 71 (SD[10.4); 75% intended to pursue third-line OAB therapy and 31 (61%) expressed interest in a specific third-line therapy. Major interview themes included a desire for a better quality of life, embarrassment with accidents, and problems with medication. Themes leading patients away from third-line OAB treatment included concern about invasiveness and side effects of treatments, and restrictions to accessing care. Conclusions: Most patients desired to progress to third-line OAB therapy, were motivated by embarrassment, but were concerned about treatment side effects. We found that economic burden of OAB treatment is associated with patient interest in and decision to receive third-line therapies to include onabotuli-numtoxinA and percutaneous tibial nerve stimulation. Improved quality of life, medication frustration, and concerns about side effects of further therapy are themes patients identified when patients considered third-line overactive bladder therapy.

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Patient Perceptions Impact Progression to Third-Line Therapy for Treatment of Overactive Bladder

et al. 2021

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“…Differences and disparities related to OAB prevalence, care-seeking behavior, and treatment by race and ethnic group are well described 78–92 . However, the degree of these differences remains unclear because of the limitations of existing research.…”

Section: Initiative 3: Health Equity and Diversitymentioning

confidence: 99%

“…Differences and disparities related to OAB prevalence, care-seeking behavior, and treatment by race and ethnic group are well described. [78][79][80][81][82][83][84][85][86][87][88][89][90][91][92] However, the degree of these differences remains unclear because of the limitations of existing research. More specifically, pooled analyses were performed while some racial and ethnic groups were either underrepresented or improperly classified.…”

Section: Initiative 3: Health Equity and Diversity Central Argumentmentioning

confidence: 99%

Evidence-Informed, Interdisciplinary, Multidimensional Action Plan to Advance Overactive Bladder Research and Treatment Initiatives: Directives From State-of-the-Science Conference on Overactive Bladder and Cognitive Impairment

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et al. 2022

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This article outlines an evidence-informed, interdisciplinary, multidimensional, comprehensive action plan for the American Urogynecologic Society to improve care of women with overactive bladder (OAB) while minimizing treatment-related adverse events, including cognitive impairment. It is a "call to action" to advance basic, translational, and clinical research and summarizes initiatives developed at the State-of-the-Science Conference on OAB and Cognitive Impairment to (1) develop framework for a new OAB treatment approach in women, (2) define research gaps and future research priorities, (3) champion health equity and diversity considerations in OAB treatment, (4) foster community and promote education to remove stigma surrounding OAB and urinary incontinence, and (5) elevate visibility and impact of OAB, by creating partnerships through education and engagement with health care professionals, industry, private and public payers, funding agencies, and policymakers.

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“…Further, the psychosocial aspects of such diseases can often affect quality of life for female patients and promote reclusive behavior and/or depression for fear of embarrassment. 2,[5][6][7][8] The economic burden on the health-care system is also a concern in light of the aging population. 6,7 Options for disease management can range from therapy to surgical intervention and often vary according to disease presentation and urological comorbidities.…”

Section: Discussionmentioning

confidence: 99%

Peripheral blood mononuclear cell gene array profiles in female patients with involuntary bladder contractions

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Bluth²,

Khan³

et al. 2011

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Prevalence and Characteristics of Overactive Bladder in Women in a Primary Care Setting

Cited by 6 publications

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Patient Perceptions Impact Progression to Third-Line Therapy for Treatment of Overactive Bladder

Patient Perceptions Impact Progression to Third-Line Therapy for Treatment of Overactive Bladder

Evidence-Informed, Interdisciplinary, Multidimensional Action Plan to Advance Overactive Bladder Research and Treatment Initiatives: Directives From State-of-the-Science Conference on Overactive Bladder and Cognitive Impairment

Peripheral blood mononuclear cell gene array profiles in female patients with involuntary bladder contractions

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