Prevalence and clinical aspects of drug-induced gingival enlargement

Abstract

Drug-induced gingival enlargement is an iatrogenic condition which is usually not preventable. Certain factors like thorough tooth brushing, proper oral hygiene measures, regular dental flossing and professional care of oral cavity are helpful. Surgical excision of the gingival overgrowth is a treatment of choice but non-surgical methods should be adopted first. More research is needed to investigate measures that can prevent or reduce gingival overgrowth or prevent recurrence. A thorough review of literature reveals that inadequate data exist pertaining to prevalence and treatment options available for iatrogenic gingival hyperplasia. Studies with large number of samples, with statistical analysis, are required to make the data more scientific. Preventive measures have limited value and require regular assessment of patients. Hyperplasia does occur after surgical intervention but percentage of recurrence is not available. Hyperplasia can be managed to a certain extent by withdrawing or changing the medication. However, surgical intervention remains the mainstay of treatment. This paper reviews various aspects of prevalence, pathogenesis and treatment options available to manage drug-induced gingival hyperplasia.

Agrandamiento gingival inducido por fenitoínas

“…doi: 10.35366/97621 INTRODUCCIÓN E l agrandamiento gingival es una condición clínica que ha sido ampliamente estudiada y está asociada de manera directa con condiciones locales o sistémicas específicas. 1 El crecimiento excesivo de la encía es principalmente un efecto adverso específico de la fenitoína, bloqueadores de los canales de calcio e inmunosupresores como la ciclosporina. 2 La patogenia del crecimiento excesivo gingival inducido por fenitoína es multifactorial.…”