Prevalence and clinical characteristics of chronic spontaneous urticaria in pediatric patients

Abstract

This study revealed a prevalence of CSU among pediatric population comparable to adults and also suggested an unmet need for approved treatments for inadequately controlled pediatric CSU patients. It is truly of concern that harmful (oral steroids) or insufficient (topical creams) treatments were frequently used despite better and guideline-recommended alternatives.

Urticaria: Collegium Internationale Allergologicum (CIA) Update 2020

“…In three studies that included both children and adults, the prevalence did not differ significantly between both age groups [4][5][6]. In a more recent study, the prevalence in children in Europe was 1.1% [7]. In a study from Korea, the prevalence in children was even higher [8].…”

Clinicoepidemiological study of chronic urticaria in a government tertiary care centre in South India

“…7 Number of patients under 10yrs of age was 1.8% only similar to Balp et al, with prevalence being 1.38% among peadiatric population. 6 Unlike Katsarou et al, showing 50% of patients with less 30 yrs of age at disease onset, only 27% were with this age of onset and 32% presented with disease onset in the 4th decade. 8 Ear, nose or throat involvement was very negligible (0.6%), unlike Zuberbier et al, showing 39.1% of patients with comorbidities like allergic rhinitis or oral allergy syndrome and Kim et al, saying allergic rhinitis as one of the most common comorbidities in chronic urticaria.…”

“…Acute spontaneous urticaria often presents in childhood. 6 Lifetime prevalence of acute and chronic urticaria range between 0.6-1.8%. 1 Cholinergic urticaria, urticaria occurring in association with sweating is common in adolescents.…”

The clinical evidence of second-generation H1-antihistamines in the treatment of allergic rhinitis and urticaria in children over 2 years with a special focus on rupatadine

“…A physician-based online survey was conducted in 5 European countries (United Kingdom, Germany, Italy, France, and Spain) to assess the prevalence and clinical characteristics of CSU in pediatric patients. The one-year diagnosed prevalence of chronic urticaria and CSU in children was 1.38% (95% CI, 0.94-1.86) and 0.75% (95% CI, 0.44-1.08), respectively [11], and CSU accounts for more than 50% of total cases of chronic urticaria in children [10].…”