Prevalence and clinical profile of angiographic coronary artery ectasia among North Indian population

Ahmed, Rasheed; Khandelwal, Gaurav; Jain, Anita; Khandelwal, Krati; Singla, Rohit

doi:10.4103/jnsbm.jnsbm_9_18

Cited by 3 publications

(6 citation statements)

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“…Similarly, in most previous studies, 16,17 Type 4 CAE was the most common except in a few studies, where Type 3 CAE was more common. 15,22 Our study concluded that smoking was strongly associated with an increased prevalence of CAE (45.3% vs 21.3%, adjusted odds ratio = 3.107, 95% CI = 2.271-4.251, P < .001). Whereas, hypertension, diabetes, dyslipidemia, and increased BMI were not associated with increased prevalence of CAE.…”

Section: Discussionmentioning

confidence: 63%

“…14 In studies from North India, South India, and Northeast India, the reported prevalence was 4.1%, 4.5%, and 5.45%, respectively. 15-17 The prevalence of isolated CAE was 1.9% in a study carried out by Nyamu et al at Chennai, India and 1.05% in a Northeast Indian study. 17,18…”

Section: Discussionmentioning

confidence: 93%

“…17,18 The mean age of presentation in our study was 60 years with male predominance which is in agreement with most previous studies. 7,[15][16][17] In our study, LAD was the most frequently involved artery by CAE, followed by RCA, LCX, and LMCA. However, diffuse ectasia was predominantly seen in RCA.…”

Section: Discussionmentioning

confidence: 99%

“…14 In studies from North India, South India, and Northeast India, the reported prevalence was 4.1%, 4.5%, and 5.45%, respectively. [15][16][17] The prevalence of isolated CAE was 1.9% in a study carried out by Nyamu et al at Chennai, India and 1.05% in a Northeast Indian study. 17,18 The mean age of presentation in our study was 60 years with male predominance which is in agreement with most previous studies.…”

Section: Discussionmentioning

confidence: 99%

“…The mean age of presentation in our study was 60 years with male predominance which is in agreement with most previous studies. 7,15-17…”

Section: Discussionmentioning

confidence: 99%

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Clinical Predictors of Coronary Artery Ectasia

et al. 2022

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Coronary artery ectasia (CAE) is defined as abnormal dilation of a coronary artery ≥1.5 times the normal segment. We aimed to determine the prevalence and clinical predictors of CAE. This was a prospective analysis performed on 6465 patients undergoing coronary angiography. Patients were divided based on the presence or absence of CAE and compared for angiographic characteristics and clinical risk factors. The prevalence of CAE was 7%, CAE associated with coronary artery stenosis was 5.4%, and isolated CAE was 1.6%. The mean age of presentation in CAE patients was 60 years, with male predominance (83.8%) and stable angina was the most common presentation. The left anterior descending artery (LAD) (51.7%) was the most commonly involved vessel, with diffuse ectasia more commonly seen in right coronary artery and discrete ectasia in LAD. Type 4 CAE was the most common type (92.4%). Hypertension, diabetes, smoking, dyslipidemia, and obesity were found in 62.4%, 35.3%, 45.3%, 54.9%, and 23.3%, respectively in CAE patients, with significant association with smoking (Odds Ratio = 3.06). The prevalence of CAE was 7% and was frequently associated with atherosclerotic coronary disease. Smoking was a significant predisposing factor for CAE.

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Section: Discussionmentioning

confidence: 63%

Section: Discussionmentioning

confidence: 93%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

“…The mean age of presentation in our study was 60 years with male predominance which is in agreement with most previous studies. 7,15-17…”

Section: Discussionmentioning

confidence: 99%

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Clinical Predictors of Coronary Artery Ectasia

et al. 2022

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Coronary Artery Ectasia

Patel

Shrivastava

Patel

et al. 2023

Indian Journal of Clinical Cardiology

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Some individuals develop a rare form of coronary heart disease called coronary artery ectasia (CAE). It is characterized by a dilation of more than one-third of the length of a coronary artery and a diameter that is 1.5 times that of the adjacent normal coronary artery. In the absence of significant coronary constriction, angina pectoris, positive stress tests, and acute coronary syndromes may all be indications of CAE. A distal embolization, vasospasm, or vascular rupture may cause thrombus formation in an ectatic artery. Antiplatelets, such as aspirin, are the cornerstone of treatment for people with CAE. Anticoagulants are used to prevent thrombus formation based on the presence of concurrent obstructive coronary artery disease and the patient’s risk of bleeding. As atherosclerosis is the most common cause of CAE, all patients are advised to take statins for primary prevention. Due to their anti-inflammatory properties, angiotensin-converting enzyme inhibitors may be prescribed to individuals with hypertension. If hypertension and coronary vasospasm occur simultaneously, beta-blockers and calcium channel blockers may be beneficial. Because they may aggravate symptoms, nitrates are normally not suggested. Other CAE treatment methods include the prevention of thromboembolic complications and percutaneous or surgical revascularization. CAE prognosis is determined on the severity of the associated coronary artery.

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Investigating the Prevalence of Ectasia in Angiographic Patients with Acute Coronary Syndrome

Farooq,

Tariq,

Aslam

et al. 2024

PJHS

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Coronary artery ectasia is dilatation of a segment of the coronary arteries leading to intense cardiac conditions. Among the patients undergoing angiography, it has a rare prevalence of 0.3 – 5.3%. It has been strongly associated with atherosclerosis as an evident cause of the dilation of coronary lumen. Objective: To determine the frequency of ectasia in patients of acute coronary syndrome undergoing coronary angiography. Methods: It is a cross sectional study conducted over six months. 160 patients from the Department of Cardiology, Mayo Hospital, Lahore were enrolled that fulfilled the study criteria of 30-70 years of age, presenting acute coronary syndrome, and undergoing angiography. The Angiography was done by an expert surgeon, simultaneously observed by one of the researchers. Ectasia was diagnosed in all the 160 based on its operational definition. Socio-demographic information including name, age, sex, diabetes (BSR>200mg/dl), hypertension (BP≥140/90mmHg), smoking, and type of acute coronary syndrome was collected with informed consent. Statistical analysis was performed using SPSS version 21. The chi-square test was practiced comparing ectasia in stratified groups of socio-demographic characters and type of acute coronary syndrome. Results: Ectasia was diagnosed in 54 (33.8%) patients. No significant association was seen between the age of patients and ectasia. However, frequency of ectasia was higher in patients in the age group 30-50 years. Frequency of ectasia was higher among male patients, but it was not statistically significant when compared with frequency of ectasia among female patients. No significant association was seen between ectasia and diabetes (p-value > 0.999), hypertension (p-value = 0.439) and smoking status (p-value = 0.140) of patients. Conclusions: Ectasia is a well-established condition of coronary artery but is an unconventional diagnostic finding of coronary angiography in patients affected with acute coronary syndromes.

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Prevalence and clinical profile of angiographic coronary artery ectasia among North Indian population

Cited by 3 publications

References 0 publications

Clinical Predictors of Coronary Artery Ectasia

Clinical Predictors of Coronary Artery Ectasia

Coronary Artery Ectasia

Investigating the Prevalence of Ectasia in Angiographic Patients with Acute Coronary Syndrome

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