Prevalence and Detection of Ureaplasma urealyticum and Mycoplasma hominis in Endocervical Specimens from Women with Genitourinary Tract Diseases in Iran

Abstract

Background: Mycoplasma can be isolated with considerable frequency from the female urogenital tracts. Ureaplasma urealyticum and Mycoplasma hominis are important genital mycoplasmas and known as sexually transmitted agents, causing mainly urethritis, pelvic inflammatory disease, spontaneous abortion, pyelonephritis, infertility, stillbirth, low birth weight, neonatal meningititis, and neonatal pneumonia. The aim of this study was to evaluate the incidence of Mycoplasma infections in women of reproductive age.Methods: Vaginal and cervical specimens were collected from 130 women, aged between 20 and 50 years, who referred to our laboratory during a 12-month period. Every woman was tested for the presence of Mycoplasma with culture method. Endocervical and vaginal swab samples were taken from patient, and transported with mycoplasma transport media then filtered and cultured on H&U agar. Isolates tested for Ureaplasma urealyticum and Mycoplasma hominis with urea and arginin hydrolysis respectively.Results: Of the 130 patients studied, 29(22.33%) were positive for U.urealyticum and 37(28.4%) were positive for M. hominis. 25(18.4%) of patients presented both organisms or both genital mycoplasmas.The highest prevalence of both organisms was seen in the married women in 21-30 age group.Conclusions: In our study there is a expected prevalence of genital Mycoplasma. Because of the potential adverse effects of mycoplasmas on the success rate of highly specialized infertility treatment, and its causal roles in several maternal complications of pregnancy and in neonatal morbidity and mortality, the detection of mycoplasmas in women could be important and necessary.

The correlation of the lifestyle and medical conditions with the vaginal infections and production of 2-phenylethanol

“…High correlation between the M. hominis and U. urealyticum was also confirmed by van der Schee et al [38]. Pordeli [39] conducted research on 130 participants with the age range from 20 and 50 years and found that 22.33 % of them were positive for U. urealyticum, 28.4 % of them to M. hominis while 18.4 % of patients were infected by both genital mycoplasmas. The highest prevalence of both microorganisms was detected in the married women ranging from 21 to 30 years, which was also in agreement with our own study.…”