Prevalence and Determinants of COVID-19 Vaccine Acceptance in South East Asia: A Systematic Review and Meta-Analysis of 1,166,275 Respondents

Yanto, Theo Audi; Lugito, Nata Pratama Hardjo; Hwei, Lie Rebecca Yen; Virliani, Cindy; Octavius, Gilbert Sterling

doi:10.3390/tropicalmed7110361

Cited by 8 publications

(8 citation statements)

References 73 publications

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“…The current study finding of a vaccine acceptance rate of 73.5%, was relatively similar to the report from South East Asia, which observed a 71% acceptance rate (35). However, it was higher than the acceptance rates reported in the United Arab Emirates, 60.1% (15), in Saudi Arabia, 44.7% (14), in Wolayta Sodo, Ethiopia, 45.5% (28), in Addis Ababa, Ethiopia, 51.8% (17-19), in the Amhara region, 54.2% (20-22), in the South Ethiopia region, 57.0% (23)(24)(25), and the pooled prevalence reports of COVID-19 vaccine acceptance in Ethiopia, 57.8 and 51.6% (29, 30).…”

Section: Discussionsupporting

confidence: 90%

COVID-19 vaccine hesitancy among adults in Hawassa City Administration, Sidama Region, Ethiopia: A community-based study

Yohannes

Alemayehu

Woldesenbet

et al. 2023

Front. Public Health

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ObjectiveThe COVID-19 vaccine is one of the key measures to control the disease. However, some people are hesitant to take the vaccine. The objective of this study was to assess COVID-19 vaccine hesitancy and associated factors among adults in Hawassa City Administration, South Ethiopia.MethodFrom March 1 to 30, 2022, we conducted a community-based cross-sectional study among randomly selected 622 adults in Hawassa City Administration. A multi-stage sampling technique was used to recruit the study participants. Data were collected through a pretested structured questionnaire that was administered by four trained high school graduates. Data entry and analysis were done using the SPSS version 20 statistical package. Descriptive statistics and logistic regression analysis were performed. Statistically significant associations were reported at p-value <0.05.ResultAmong the participants, 400 of them (64.3%) had a high level of knowledge about the COVID-19 vaccine) and 425 of them (68.3%) had a positive attitude toward the COVID-19 vaccine. The level of vaccine hesitancy was 165 (26.5%) and vaccine acceptance was 457 (73.5%). The main reason for willingness to take the vaccine was to protect oneself from COVID-19 (364 participants, 58.5%), and for unwillingness, it was fear of the vaccine (154 participants, 24.8%). Mass media was the main source of information about the vaccine (472 participants, 75.9%). Age (adjusted odds ratio (AOR): 2.1, 95% CI: 1.2–3.7), religion (AOR: 2.6, 95% CI: 1.1–5.9), history of COVID-19 disease (AOR: 4.6, 95% CI: 1.4–14.9), knowledge related to the COVID-19 vaccine (AOR: 1.9, 95% CI: 1.2–3.1), and attitude toward the COVID-19 vaccine (AOR: 13.2, 95% CI: 8.3–20.9) were factors associated with vaccine hesitancy.ConclusionA low proportion of COVID-19 vaccine hesitancy was observed among our study participants. Improving people's awareness could help to improve vaccine acceptance. It is important to focus interventions on the identified risk factors of vaccine hesitancy.

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Section: Discussionsupporting

confidence: 90%

COVID-19 vaccine hesitancy among adults in Hawassa City Administration, Sidama Region, Ethiopia: A community-based study

Yohannes

Alemayehu

Woldesenbet

et al. 2023

Front. Public Health

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“…The countries with the highest rates of COVID-19 vaccine acceptance among the adult population are Ecuador (97.0%), Malaysia (94.3%), Indonesia (93.3%), and China (91.3%) [ 69 ]. This data contrast with results from another study, with only 78% vaccination acceptance for Malaysia and 67% for Indonesia [ 70 ]. The vaccination acceptance in Indonesia (67%) aligns closely with the COVID-19 vaccination status in Indonesia (62.5% completely vaccinated) at the time of the study’s publication [ 70 ].…”

Section: Background and Key Issues Of The Covid-19 Pandemic In Indonesiacontrasting

confidence: 99%

“…This data contrast with results from another study, with only 78% vaccination acceptance for Malaysia and 67% for Indonesia [ 70 ]. The vaccination acceptance in Indonesia (67%) aligns closely with the COVID-19 vaccination status in Indonesia (62.5% completely vaccinated) at the time of the study’s publication [ 70 ]. Of note, the acceptance of COVID-19 vaccination, in general, does not necessarily translate into actual vaccination uptake.…”

Section: Background and Key Issues Of The Covid-19 Pandemic In Indonesiacontrasting

confidence: 99%

From Archipelago to Pandemic Battleground: Unveiling Indonesia’s COVID-19 Crisis

Harapan,

Theodora

et al. 2023

J Epidemiol Glob Health

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The coronavirus disease 2019 (COVID-19) pandemic has posed unprecedented challenges to countries worldwide, including Indonesia. With its unique archipelagic geography consisting of more than 17,000 thousand islands, Indonesia faces unique complexities in managing the spread of the virus. Based on existing literature, this review article elaborates on key issues that have shaped Indonesia’s COVID-19 response. The article begins by examining the early stages of the COVID-19 pandemic in Indonesia, along with the implementation of various preventive measures and the impact of the virus on public health. This article examines how Indonesia’s socio-economic factors have generally influenced its healthcare system and further delves into the COVID-19 response strategies implemented by the Indonesian government and public health authorities as well as overall crisis preparedness. It discusses the actions taken to control the spread of the virus, including testing strategies and vaccination efforts. The difficulties encountered in implementing these measures are presented. In conclusion, this review article provides a comprehensive understanding of the COVID-19 crisis in Indonesia, covering facts on multiple dimensions ranging from the timeline of the pandemic to vaccination efforts, epidemiology, socio-economic implications, testing strategies, mobility patterns, public holidays, the impact of working from home, and the utilization of complementary and alternative medicine in addition to the standard of care for COVID-19. The insights gained from this article can complement future strategies for pandemic management and response in Indonesia and other countries facing similar challenges.

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“…Table S3 in Multimedia Appendix 2 [9][10][11][12][13][14][15][16][17] presents an overview of all included meta-analyses published between 2021 and 2023. These studies looked at different groups, such as the general population; health care workers; parents; pregnant women; migrant workers; Black or African communities; Chinese communities; and people with specific health conditions such as cancer, HIV, diabetes, inflammatory bowel disease, and epilepsy.…”

Section: Characteristics Of Meta-analyses and Quality Assessmentmentioning

confidence: 99%

“…Recognizing the pivotal role of vaccine acceptance in the trajectory of the pandemic, it becomes imperative to understand the nuances of global vaccine perceptions. Numerous systematic reviews and meta-analyses have been published, shedding light on factors that are driving vaccine hesitancy and acceptance [8][9][10][11][12][13][14][15][16][17].…”

Section: Introductionmentioning

confidence: 99%

COVID-19 Vaccine Hesitancy: Umbrella Review of Systematic Reviews and Meta-Analysis

Rahbeni,

Satapathy,

Itumalla

et al. 2024

JMIR Public Health Surveill

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Background The unprecedented emergence of the COVID-19 pandemic necessitated the development and global distribution of vaccines, making the understanding of global vaccine acceptance and hesitancy crucial to overcoming barriers to vaccination and achieving widespread immunization. Objective This umbrella review synthesizes findings from systematic reviews and meta-analyses to provide insights into global perceptions on COVID-19 vaccine acceptance and hesitancy across diverse populations and regions. Methods We conducted a literature search across major databases to identify systematic reviews and meta-analysis that reported COVID-19 vaccine acceptance and hesitancy. The AMSTAR-2 (A Measurement Tool to Assess Systematic Reviews) criteria were used to assess the methodological quality of included systematic reviews. Meta-analysis was performed using STATA 17 with a random effect model. The data synthesis is presented in a table format and via a narrative. Results Our inclusion criteria were met by 78 meta-analyses published between 2021 and 2023. Our analysis revealed a moderate vaccine acceptance rate of 63% (95% CI 0.60%-0.67%) in the general population, with significant heterogeneity (I2 = 97.59%). Higher acceptance rates were observed among health care workers and individuals with chronic diseases, at 64% (95% CI 0.57%-0.71%) and 69% (95% CI 0.61%-0.76%), respectively. However, lower acceptance was noted among pregnant women, at 48% (95% CI 0.42%-0.53%), and parents consenting for their children, at 61.29% (95% CI 0.56%-0.67%). The pooled vaccine hesitancy rate was 32% (95% CI 0.25%-0.39%) in the general population. The quality assessment revealed 19 high-quality, 38 moderate-quality, 15 low-quality, and 6 critically low-quality meta-analyses. Conclusions This review revealed the presence of vaccine hesitancy globally, emphasizing the necessity for population-specific, culturally sensitive interventions and clear, credible information dissemination to foster vaccine acceptance. The observed disparities accentuate the need for continuous research to understand evolving vaccine perceptions and to address the unique concerns and needs of diverse populations, thereby aiding in the formulation of effective and inclusive vaccination strategies. Trial Registration PROSPERO CRD42023468363; https://tinyurl.com/2p9kv9cr

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Prevalence and Determinants of COVID-19 Vaccine Acceptance in South East Asia: A Systematic Review and Meta-Analysis of 1,166,275 Respondents

Cited by 8 publications

References 73 publications

COVID-19 vaccine hesitancy among adults in Hawassa City Administration, Sidama Region, Ethiopia: A community-based study

COVID-19 vaccine hesitancy among adults in Hawassa City Administration, Sidama Region, Ethiopia: A community-based study

From Archipelago to Pandemic Battleground: Unveiling Indonesia’s COVID-19 Crisis

COVID-19 Vaccine Hesitancy: Umbrella Review of Systematic Reviews and Meta-Analysis

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