Prevalence and Determinants of Fatigue Following Total Knee Replacement: A Longitudinal Cohort Study

Hodges, Alison; Harmer, Alison R.; Dennis, Sarah; Nairn, Lillias; March, Lyn; Crosbie, Jack; Crawford, Ross; Parker, David; Fransen, Marlene

doi:10.1002/acr.22861

Cited by 11 publications

(24 citation statements)

References 29 publications

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“…The results of this study were in line with those of Murphy et al’s () study, which found that the association between pain severity and physical function differs throughout the day, indicating that physical function is a mediating variable between pain and quality of life. Nevertheless, the relationship between pain and fatigue was in accordance with other studies, in which knee pain was associated with fatigue (Hodges et al, ; Murphy et al, ). Fatigue is a common feature of chronic conditions (Engberg, Segerstedt, Waller, Wennberg, & Eliasson, ; MacKean, Stewart, & Maddocks, ).…”

Section: Discussionsupporting

confidence: 91%

“…Progressive physical limitations and disability lead to diminished quality of life (Mesci, Icagasioglu, Mesci, & Turgut, ). Pain subsequent to knee OA also impacts well‐being through incremental fatigue (Hodges et al, ), distress, and depressive symptoms, again affecting quality of life (Sugai et al, ). The symptom cluster of pain, fatigue, and depressive symptoms is related to functional status and quality of life among older people with knee OA (Jenkins & McCoy, ).…”

Section: Introductionmentioning

confidence: 99%

“…The consequences of pain have a profound influence on both the physical and mental dimensions of health and quality of life, and pain is a predominant symptom in those with knee OA (Alkan et al, ; Pang et al, ). Pain impacts both physical functioning and psychological status, mainly by increasing fatigue (Hodges et al, ), distress, and depressive symptoms (Sugai et al, ). Depressive symptoms are a common experience in chronic conditions, including knee OA, and up to 19.9% of people with knee OA suffer from depressive symptoms (Stubbs, Aluko, Myint, & Smith, ).…”

Section: Introductionmentioning

confidence: 99%

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Path model of factors influencing health‐related quality of life among older people with knee osteoarthritis

Aree‐Ue

Kongsombun

Roopsawang

et al. 2019

Nursing & Health Sciences

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Chronic illness has a significant effect on quality of life, and a critical measure of health outcomes. Correlations between pain, depressive symptoms, fatigue, and physical function and their direct and indirect effects on quality of life were determined among 200 Thai older population with knee osteoarthritis using the Numeric Rating Scale, the Multidimensional Assessment of Fatigue, and the Thai Geriatric Depression Scale‐15. Physical function was investigated by using the Timed Up and Go test. Path analysis revealed significant negative direct paths from pain, depressive symptoms, fatigue, and Timed Up and Go test results to quality of life. Pain, fatigue, and the Timed Up and Go test results had indirect effects on quality of life, while depressive symptoms had no indirect effect on quality of life. Increases in pain, depressive symptoms, fatigue, and Timed Up and Go test results were associated with reductions in quality of life. An understanding of the complex relationship among these variables is beneficial for designing an appropriate intervention for improving quality of life among older people with knee osteoarthritis.

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Section: Discussionsupporting

confidence: 91%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Path model of factors influencing health‐related quality of life among older people with knee osteoarthritis

Aree‐Ue

Kongsombun

Roopsawang

et al. 2019

Nursing & Health Sciences

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“…A “0” on the fatigue VAS was defined as “no fatigue” and “10” was defined as “fatigue as bad as it can be” with higher values indicating greater fatigue severity. The VAS fatigue scale has been commonly used in OA research and it is also a valid, reliable and responsive tool for subjective measurement such as fatigue . Further, in rheumatic diseases, VAS fatigue strongly correlates with other fatigue measures such as the Multidimensional Assessment of Fatigue at 0.80, Short‐Form 36 vitality subscale (SF‐36 VT) at 0.71 and the Multidimensional Fatigue Inventory (MFI)‐total and MFI‐general fatigue at 0.62‐0.70 …”

Section: Methodsmentioning

confidence: 99%

“…Fatigue is a commonly reported symptom and a major contributor to substantial disability and decreased quality of life among individuals with knee osteoarthritis (OA) . Generalized fatigue affects almost half of adults with OA and its prevalence has been reported to be as high as 40% . Individuals with OA describe fatigue as a symptom that considerably impacts daily functioning, social life and all aspect of daily living .…”

Section: Introductionmentioning

confidence: 99%

Determinants of generalized fatigue in individuals with symptomatic knee osteoarthritis: The MOST Study

et al. 2020

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Aim:The aim of the study was to identify sociodemographic, disease-related, physical and mental health-related determinants of fatigue at 2-year follow-up in individuals with symptomatic knee osteoarthritis (OA). Methods:A longitudinal analysis of participants with symptomatic knee OA from the Multicenter Osteoarthritis Study (MOST) was conducted to identify predictors of fatigue at 2-year follow-up. Participants self-reported fatigue at baseline for the first time in the MOST cohort and at follow-up using a 0-10 visual analog scale. At baseline, questionnaires on sociodemographics, disease-related symptoms, physical and mental health factors were completed. Data were analyzed using linear regressions with a backwards elimination approach. Results: Of the 2330 individuals in the MOST cohort at baseline, 576 had symptomatic knee OA and of these, 449 with complete fatigue values at baseline and follow-up were included in this analysis. Minimally important fatigue change (ie, worsening [≥1.13], no change [<0.82 or <1.13] and improvement [≥−0.82]) from baseline to follow-up were unequal within the population (34.5%, 26.9%, 38.5%; χ 2 [2, N = 449] = 9.32, P = .009). The multiple linear regression showed that baseline fatigue (unstandardized coefficient [Β] = 0.435; 95% confidence interval [CI] 0.348-0.523, P < .001), slow gait speed (Β = −1.124; 95% CI −1.962 to −0.285, P = .009), depressive symptoms (Β = 0.049; 95% CI 0.024-0.075, P < .001) and higher numbers of comorbidities (Β = 0.242; 95% CI 0.045-0.439, P = .016) were significant predictors of greater fatigue at follow-up. Conclusion: Fatigue is strongly associated with physical-and mental-related health factors. Individualized treatments that include combined psychological and physical function rehabilitation might be modalities for fatigue management. K E Y W O R D S fatigue, knee osteoarthritis, longitudinal, risk factors

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Sedentary behaviour among elderly patients after total knee arthroplasty and its influencing factors

Ni,

Shi,

et al. 2024

Sci Rep

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To understand the status of sedentary behaviour in elderly patients after total knee arthroplasty and analyse its influencing factors so as to provide a reference for developing targeted interventions. Conveniently selected elderly patients undergoing total knee arthroplasty (> 6 months) in a tertiary hospital in Jiangsu Province were investigated using a general information questionnaire, the Charlson Comorbidity Index, patients’ self-reported sedentary behaviour information, the WOMAC Score, The Groningen Orthopaedic Social Support Scale, and Lee’s Fatigue. The median daily sedentary time was 5.5 h (4.5 h, 6.625 h) in 166 elderly patients after total knee arthroplasty, of whom 82 (49.40%) showed sedentary behaviour (≥ 6 h per day). Logistic regression analysis showed that being retired/unemployed (OR = 8.550, 95% CI 1.732–42.207, P = 0.0084), having a CCI score ≥ 3 (OR = 9.018, 95% CI 1.288–63.119, P < 0.0001), having high WOMAC scores (OR = 1.783, 95% CI 1.419–2.238, P < 0.0001), having a high social support score (OR = 1.155, 95% CI 1.031–1.294, P = 0.0130), and having a fatigue score ≥ 5 (OR = 4.848, 95% CI 1.084–21.682, P = 0.0389) made patients more likely to be sedentary. The sedentary time of elderly patients after total knee arthroplasty is long, and sedentary behaviour is common among them. Healthcare professionals should develop targeted sedentary behaviour interventions based on the influencing factors of sedentary behaviour in order to reduce the occurrence of sedentary behaviour in elderly patients after total knee arthroplasty.

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Prevalence and Determinants of Fatigue Following Total Knee Replacement: A Longitudinal Cohort Study

Abstract: Among patients undergoing TKR for OA, clinically important fatigue is considerably prevalent both before and for at least 6 months after surgery. Identifying and addressing early predictors of ongoing fatigue has the potential to improve the quality of life following TKR surgery.

Cited by 11 publications

References 29 publications

Path model of factors influencing health‐related quality of life among older people with knee osteoarthritis

Path model of factors influencing health‐related quality of life among older people with knee osteoarthritis

Determinants of generalized fatigue in individuals with symptomatic knee osteoarthritis: The MOST Study

Sedentary behaviour among elderly patients after total knee arthroplasty and its influencing factors

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