Prevalence and Diagnosis of Molar-Incisor-Hypomineralisation (MIH): A systematic review

Jälevik, Birgitta

doi:10.1007/bf03262714

Cited by 287 publications

(297 citation statements)

References 18 publications

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“…Although the results of epidemiological studies from different countries are not directly comparable because of variations in criteria, sample selection, lesions included, and aetiological and environmental factors, the prevalence of MIH in this study (24%) fell within the wide range of values (2.8-40.2%) reported in the literature (14). However, the sample examined in this study comprised a small population of children attending our department for dental care.…”

Section: Prevalence Of Mihmentioning

confidence: 57%

“…Previous studies have explained this finding with reference to the likelihood that an erupted tooth with MIH will deteriorate quickly; thus, fewer teeth with moderate or severe MIH are typically detected (3,14,17).…”

Section: Clinical Characteristics Of Mihmentioning

confidence: 98%

“…Premda se rezultati epidemioloških istraživanja iz drugih zemalja ne mogu neposredno usporediti zbog varijacija u kriterijima, odabiru uzorka, uključenim lezijama te etiološkim i okolišnim čimbenicima, prevalencija MIH-a u ovom istraži-vanju (24 %) može se uvrstiti u široki raspon (2,8 -40,2 %) opisan u literaturi (14).…”

Section: Prevalencija Mih-aunclassified

“…Ovi rezultati u skladu su s ranijim istraživanjima provedenima u Turskoj (13). Kao i u ostalim istraživanjima (14,17), najviše je bilo blagih defekata (76 %). U dosadašnjim istraživanjima objašnjeno je da zub s MIH-om brzo propada u ustima, stoga manje zuba s blagim ili teškim MIH-om se tipično otkriju (3,14,17).…”

Section: Prevalencija Mih-aunclassified

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Possible Medical Aetiological Factors and Characteristics of Molar Incisor Hypomineralisation in a Group of Turkish Children

Borić

2013

Acta Stomatol Croat

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Section: Prevalence Of Mihmentioning

confidence: 57%

Section: Clinical Characteristics Of Mihmentioning

confidence: 98%

Section: Prevalencija Mih-aunclassified

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Possible Medical Aetiological Factors and Characteristics of Molar Incisor Hypomineralisation in a Group of Turkish Children

Borić

2013

Acta Stomatol Croat

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“…3,4,5 The prevalence of MIH has been studied extensively and it varies greatly from 2.4% in Germany and Bulgaria to 40.2% in Brazil. 6 The condition shows no gender predilection and the maxillary teeth, most specifically the molars, are most commonly affected. 7 The FPMs may not be affected to the same degree in an individual and some molars could be relatively unaffected.…”

Section: Introductionmentioning

confidence: 99%

Molar Incisor Hypomineralization in Monozygotic Twins: A Case Report

Velissariou¹,

Chandwani²

2017

EDUJ

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Aim: The aim of this case report is to discuss the features of molar incisor hypomineralization (MIH), a developmental enamel defect, which was noted in a set of monozygotic twin males. Summary: MIH is the hypomineralization of one to four first permanent molars (FPMs) frequently associated with affected incisors and varies in clinical severity. Early diagnosis and management of the condition is paramount and will avoid the premature loss of the molars. Key learning points: The clinical characteristics, as well as the short and long term management of this condition are discussed.

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Association of High-Dose Vitamin D Supplementation During Pregnancy With the Risk of Enamel Defects in Offspring

et al. 2019

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IMPORTANCE Enamel defects of developmental origin affect up to 38% of schoolchildren and is recognized as a global public health challenge. The impaired enamel formation results in pain owing to hypersensitivity, posteruptive breakdowns, rapid caries progression, and extractions in some cases. The etiology is unknown; therefore, prevention is currently not possible.OBJECTIVE To assess the association of a high-dose vitamin D supplementation in pregnant women with enamel defects and caries in their offspring. DESIGN, SETTING, AND PARTICIPANTS Post hoc analysis of a double-blind, single-center, randomized clinical trial, the Copenhagen Prospective Studies on Asthma in Childhood 2010 cohort (COPSAC 2010 ). Enrollment began March 2009 and included 623 women recruited at 24 weeks of pregnancy and 588 of their children. A dental examination was completed at age 6 years in 496 of 588 children (84%). Data were analyzed in 2018. INTERVENTION High-dose vitamin D 3 (2400 IU/d; N = 315) or matching placebo tablets (N = 308) from pregnancy week 24 to 1 week post partum. In addition, all women received 400 IU/d of vitamin D 3 as part of standard care.MAIN OUTCOMES AND MEASURES Enamel defect was defined as having at least 1 molar affected by demarcated opacity, enamel breakdown, and/or atypical restoration. Caries was defined as decayed, missing, or filled surfaces in both the deciduous and permanent dentitions (World Health Organization standard). RESULTSThe risk of enamel defects in the permanent dentition was lower in the offspring of mothers who received high-dose vitamin D supplementation during pregnancy compared with standard dose (15.1% [n = 26 of 172] vs 27.5% [n = 44 of 160]; odds ratio, 0.47; 95% CI, 0.27-0.81). A similar association was observed for the deciduous dentition (8.6% [n = 21 of 244] vs 15.9% [n = 40 of 252]; odds ratio, 0.50; 95% CI, 0.28-0.87). There was no association between supplementation and caries.CONCLUSIONS AND RELEVANCE High-dose vitamin D supplementation during pregnancy was associated with approximately 50% reduced odds of enamel defects in the offspring. This suggests prenatal vitamin D supplementation as a preventive intervention for enamel defects, with a clinically important association with dental health.TRIAL REGISTRATION ClinicalTrials.gov identifier: NCT00856947

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Prevalence and Diagnosis of Molar-Incisor-Hypomineralisation (MIH): A systematic review

Abstract: Further standardization of study design and methods is needed to make the results comparable.

Cited by 287 publications

References 18 publications

Possible Medical Aetiological Factors and Characteristics of Molar Incisor Hypomineralisation in a Group of Turkish Children

Possible Medical Aetiological Factors and Characteristics of Molar Incisor Hypomineralisation in a Group of Turkish Children

Molar Incisor Hypomineralization in Monozygotic Twins: A Case Report

Association of High-Dose Vitamin D Supplementation During Pregnancy With the Risk of Enamel Defects in Offspring

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