Prevalence and distribution of canine neoplastic and non-neoplastic cutaneous lesions in Serbia: a retrospective study of 2432 Cases (2011 – Mid 2021)

Abstract

Cutaneous lesions, especially skin tumors in dogs, are among the most common lesions in this animal species. The aim of this study was to identify the most common types of canine cutaneous lesions, to determine the absolute and relative frequency of each type of cutaneous lesion, anatomical locations, mean age, as well as gender and breed distribution. The examination included all samples of cutaneous lesions in dogs obtained by surgical biopsy in veterinary clinics and examined at the Laboratory of the Department of Pathology at the Faculty of Veterinary Medicine, University of Belgrade from the 1st January 2011 to the 1st July 2021. In this period (126 months), a total of 2432 samples of cutaneous lesions were examined, of which 1984 (81.58%) were tumors (1037/1984, 52.27% benign and 947/1984, 47.73% malignant) and 448 (18.42%) non-neoplastic cutaneous lesions. The most commonly found cutaneous tumors were: mast cell tumor (17.34% of all tumors), histiocytoma (9.78%), papilloma (7.91%), lipoma (7.81%), squamous cell carcinoma (7.36%), trichoblastoma (4.44%), hepatoid adenoma (4.39%) and malignant melanoma (4.18%). The most common non-neoplastic cutaneous lesions were: follicular cyst(s) (35.04% of all non-neoplastic lesions), pyogranulomatous chronic dermatitis (23.88%), lymphocytic dermatitis (7.37%), hyperkeratosis (4.24%), and granulomatous dermatitis (3.79%). Our results substantially confirm previously reported data regarding cutaneous neoplastic and nonneoplastic lesions in dogs, and provide updated information on their frequency, animal age, anatomic location and breed distributions.

Histomorphological changes in atheroma of the dog (morphological study on the example of 12 clinical cases)

“…The study by M. Patel et al (2019) indicates that the pathology of the sebaceous glands accounted for 4.04% of cases of all skin diseases in dogs, while out of 23 cases, three adenocarcinomas and one hyperplasia (atheroma) were diagnosed in 19 cases. In other studies, V. Kukolj et al (2021) indicate that pathological changes in the sebaceous glands had a slightly different proportion. Thus, out of 2432 skin biopsies in dogs, a cyst was detected in 35% of cases, and an adenoma -only in 4.4%.…”

Untitled

“…The observed phenomenon of heterogeneity of the morphological structure of the corpora lutea of the heifer's ovaries by differential palpation in vivo, has become an opportunity to explain the pathogenesis of hypotrophic changes in tissues due to sclerotisation of the walls of blood vessels, both arterial and venous, which was histologically confirmed by O.A. Baban et al (2021). Microanatomical examination of the ovaries of heifers with symptoms of anaphrodisia revealed a characteristic decrease in the density of follicular cells in the primary follicles around the oocytes and the formation of gaps between them.…”

“…8). of the sexual cycle (2021)(2022) The substantial impact of seasonal factors on the ovarian luteogenesis of heifers of mating age prompted a more detailed consideration of the morphology of corpus luteum, which had clear functional characteristics.…”

“…According to O.A. Baban et al (2021), a decrease in the size of the ovaries of cows may be associated with hypotrophy, i.e., a decrease in the size of the cells of the tissues of the cerebral and cortical layers or hypoplasia. B.M.…”

“…Jaśkowski (2019) explains this phenomenon by a decrease in the number of cells due to functional formations of different phases of the cycle, namely follicular or luteal. According to A.M. Getahun et al (2021), there are no criteria for the differential diagnosis of these pathological phenomena in gonadal morphology at the macro level, which is determined by significant differences in the diagnosis of hypotrophic changes in the ovaries of cows, in particular, heifers of breeding age. S.Y.…”