Prevalence and factors correlated with hypertension secondary from obstructive sleep apnea

Abstract

Background: In 2003, the JNC 7 reported obstructive sleep apnea (OSA) as a cause of secondary hypertension. The prevalence of OSA in hypertension ranges from 30-80%. There are limited data on the prevalence and risk factors of OSA in hypertensive patients. This study thus aimed to evaluate prevalence and clinical predictors of obstructive sleep apnea (OSA) in these patients.Methods: This was a cross-sectional study and conducted at the hypertension clinic at Khon Kaen University’s Srinagarind Hospital, Thailand. We enrolled patients with hypertension treated at the clinic. OSA was defined as apnea-hypopnea index of 5 events/hour or over according to cardiopulmonary monitoring. Patients whose hypertension was due to any other causes were excluded. The prevalence of OSA was calculated and risk factors for OSA were analyzed using multivariate logistic regression.Results: There were 726 hypertensive patients treated at the clinic. Of those, 253 (34.8%) were randomly studied and categorized as either non-OSA (147 patients, 58.1%) or OSA (106 patients, 41.9%). There were four independent factors associated with OSA-induced hypertension: age, sex, history of snoring, and history of headache. Headache had an adjusted odds ratio (95% confidence interval) of 3.564 (95% confidence interval of 1.510, 8.411).Conclusion: Age, male sex, history of snoring, and headache were independent predictors of hypertension caused by OSA.

Factors associated with favorable outcomes in acute severe stroke patients: A real‑world, national database study

“…Third, the outcomes were evaluated only at discharge and not over a longer term. Fourth, some factors possibly related to both stroke and atrial fibrillation were not examined such as laboratory tests and obstructive sleep apnea (25)(26)(27)(28)(29)(30)(31)(32)(33). Finally, authorization to access the database was only for the mentioned study period (2015-2017).…”

Editorial: Clinical aspects of obstructive sleep apnea and cardiovascular consequences

“…The authors also found that obesity was not related to severity of OSA in older adults. Previous studies also showed that obesity may not be related to OSA diagnosis particularly in the elderly and those with hypertension ( 52 , 61 ). Xia et al conducted a retrospective study to show that both low oxygenation and arousal during apneic events in patients with OSA were significantly related to high diastolic blood pressure and hypertension.…”

“…This Research Topic focused on clinical aspects of cardiovascular diseases including review, epidemiological, treatment-related, or interventional studies. Cardiovascular consequences of OSA included hypertension, coronary artery disease, cardiac arrhythmia, left ventricular hypertrophy, cardiac failure, and stroke ( 52 – 60 ).…”

Long Term Efficacy of Generic Atorvastatin by a University Hospital Database

“…A report from UK found that 21.3% of 1,275,174 adult patients had one of the cardiovascular diseases [1]. Dyslipidemia is one of the major risk factors for cardiovascular diseases as well as other risk factors such as hypertension or sleep apnea [2], [3], [4], [5]. The previous reports and guidelines recommended lowering low-density lipoprotein cholesterol (LDL-c) in both primary and secondary prevention [6], [7].…”