Prevalence and Factors Related to Hepatitis B and C in Inflammatory Bowel Disease Patients in Spain: A Nationwide, Multicenter Study

Loras, Carme; Saro, Cristina; González-Húix, Ferrán; Mínguez, Miguel; Merino, Olga; Gisbert, Javier P.; Barrio, Jesús; Bernal, Antonio; Gutiérrez, Ana; Piqueras, Marta; Calvet, Xavier; Andreu, Montserrat; Abad, Águeda; Ginard, Daniel; Bujanda, Luís; Panés, Julián; Torres, Mauricio Plaza; Fernández‐Bañares, Fernando; Viver, Josep Maria; Esteve, María

doi:10.1038/ajg.2008.4

Cited by 132 publications

(136 citation statements)

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“…Several studies have documented poor uptake of routine vaccinations among patients with IBD ( 14,20 ). In one study of 169 IBD patients seen at an IBD center, of 145 patients on current or previous immunosuppression, only 28% reported regular fl u shots and only 9% received the pneumococcal vaccine ( 14 ).…”

Section: Vaccinationsmentioning

confidence: 99%

“…Common reasons for low rates of vaccination included patient lack of awareness and fear of side eff ects. In another study of 2076 IBD patients in Spain, only 12% of patients were vaccinated against hepatitis B ( 20 ).…”

Section: Vaccinationsmentioning

confidence: 99%

“…Th e package insert for vedolizumab states that patients on this biologic agent may receive non-live vaccines (e.g., infl uenza vaccine injection, etc) and may receive live vaccines if the benefi ts outweigh the risks ( https:// entyviohcp.com/?gclid=CJLM_o6Nj-MoCFZFgfgodybALFw ). Several studies have documented poor uptake of routine vaccinations among patients with IBD ( 14,20 ). In one study of 169 IBD patients seen at an IBD center, of 145 patients on current or previous immunosuppression, only 28% reported regular fl u shots and only 9% received the pneumococcal vaccine ( 14 ).…”

mentioning

confidence: 99%

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ACG Clinical Guideline: Preventive Care in Inflammatory Bowel Disease

Farraye

Melmed

Lichtenstein

et al. 2017

American Journal of Gastroenterology

403

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Recent data suggest that infl ammatory bowel disease (IBD) patients do not receive preventive services at the same rate as general medical patients. Patients with IBD often consider their gastroenterologist to be the primary provider of care. To improve the care delivered to IBD patients, health maintenance issues need to be co-managed by both the gastroenterologist and primary care team. Gastroenterologists need to explicitly inform the primary care provider of the unique needs of the IBD patient, especially those on immunomodulators and biologics or being considered for such therapy. In particular, documentation of up to date vaccinations are crucial as IBD patients are often treated with long-term immune-suppressive therapies and may be at increased risk for infections, many of which are preventable with vaccinations. Health maintenance issues addressed in this guideline include identifi cation, safety and appropriate timing of vaccinations, screening for osteoporosis, cervical cancer, melanoma and non-melanoma skin cancer as well as identifi cation of depression and anxiety and smoking cessation. To accomplish these health maintenance goals, coordination between the primary care provider, gastroenterology team and other specialists is necessary. of evidence, we entered data from the papers of highest evidence into the GRADE program (accessible at http://www.gradepro.org ). Th e recommendation statements from this guideline are shown in Table 1 . Summary statements, when listed, are designed to be descriptive in nature without associated evidence-based ratings. VACCINATIONSRecent data suggest that IBD patients do not receive preventive services at the same rate as general medical patients ( 2 ). Members of the gastroenterology team are oft en the only clinicians that a patient with IBD will see. As such, it is incumbent upon gastroenterologists to take a proactive role in the health care needs of their IBD patients ( 3-5 ). It is crucial to clarify with the patient the limits of the specialist's responsibilities and delegate routine health care issues to the primary care clinician. It is equally important to educate the primary care clinician to the unique health maintenance needs of the IBD patient, especially those on immunomodulators and biologic agents. Although it appears that both primary care clinicians and gastroenterologists are hesitant to take ownership of vaccinations ( 6-8 ), it is reasonable ( 9 ) that vaccination recommendations be the responsibility of the treating gastroenterologist, but the actual delivery/administration of these vaccines may be a shared responsibility ( 10-13 ). Communicating specifi c recommendations to the primary care team in a concise fashion are needed. Consider empowering the patient by giving written recommendations to bring to their primary care physician. Clinicians sharing an electronic medical record should use this platform to send recommendations to the referring clinician.Patients with IBD are oft en treated with long-term immunesuppressive therapies and may t...

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Section: Vaccinationsmentioning

confidence: 99%

Section: Vaccinationsmentioning

confidence: 99%

mentioning

confidence: 99%

See 1 more Smart Citation

ACG Clinical Guideline: Preventive Care in Inflammatory Bowel Disease

Farraye

Melmed

Lichtenstein

et al. 2017

American Journal of Gastroenterology

403

421

View full text Add to dashboard Cite

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“…In contrast, other studies have reported HBV exposure rates in IBD patients that were similar to those of the general population. REPENTINA 1, a recent large-scale cross-sectional multicentre study of 2076 IBD patients consecutively recruited at 17 Spanish hospitals, 6 found the prevalence of HBV infection to be lower than that reported in previous studies (less than 1% hepatitis B surface antigen (HBsAg)-positive and less than 10% anti-HBc-positive). However, no differences were found between CD and UC, in contrast with other studies, where the prevalence of HBV markers was higher in CD than in UC.…”

Section: What Is the Prevalence Of Hbv And Hcv Infection In Ibd Patiementioning

confidence: 85%

“…2 Studies evaluating the prevalence of HBV infection in patients with IBD are summarised in Table 1. 2,[6][7][8][9] The weighted mean prevalence of HBsAg-positive infection in the five studies included (total population, 3121 patients) was 1%. The corresponding mean value for anti-HBcpositive infection was 8.1%.…”

Section: What Is the Prevalence Of Hbv And Hcv Infection In Ibd Patiementioning

confidence: 99%