Prevalence and Genetic Diversity of &lt;b&gt;&lt;i&gt;Aichi Virus 1&lt;/i&gt;&lt;/b&gt; from Urban Wastewater in Senegal

Kébé, Ousmane; Fernandez-Garcia, Maria Dolores; Fall, Amary; Dia, Hamet; Bidalot, Maxime; Ambert-Balay, Katia; Ndiaye, Kader

doi:10.1159/000512130

Cited by 8 publications

(4 citation statements)

References 39 publications

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“…Aichivirus (AiV) belongs to the Kobuvirus genus and the family Picornaviridae ( Rivadulla and Romalde, 2020 ). It is one of the significant causative organisms of gastroenteritis in humans and is transmitted via the faecal-oral route from contaminated food or water ( Yamashita et al, 2000 ; Adams et al, 2013 ; Kebe et al, 2021 ). Aichivirus consists of Human AiV (HAiV) 1, Murine Kobuvirus (MuKV) 1, and Canine Kobuvirus (CaKV) 1.…”

Section: Enteric Viruses Of Public Health Importancementioning

confidence: 99%

“…Aichivirus consists of Human AiV (HAiV) 1, Murine Kobuvirus (MuKV) 1, and Canine Kobuvirus (CaKV) 1. Human AiV is composed of three genotypes (A–C; Yamashita et al, 2000 ; Shaheen et al, 2020 ; Kebe et al, 2021 ), and the infection rate of AiV in gastroenteritis cases worldwide is low between 0.4 and 6.5% ( Rivadulla and Romalde, 2020 ; Taghinejad et al, 2020 ; Upfold et al, 2021 ). However, specific antibodies produced against the virus are found in about 80–90% of adults ( Kitajima and Gerba, 2015 ; Rivadulla and Romalde, 2020 ), which is a pointer to the asymptomatic condition of most infections ( Bergallo et al, 2017 ).…”

Section: Enteric Viruses Of Public Health Importancementioning

confidence: 99%

“…Aichivirus has been reported in Africa, Asia, South America, and Europe ( Oh et al, 2006 ; Lodder et al, 2013 ). The virus is normally passed out in the faeces of humans directly or after discharge of treated or untreated sewage ( Lodder et al, 2013 ; Kebe et al, 2021 ), and can be adopted as a potential indicator of wastewater reclamation system ( Kitajima et al, 2014 ; Farkas et al, 2020b ).…”

Section: Enteric Viruses Of Public Health Importancementioning

confidence: 99%

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Global public health implications of human exposure to viral contaminated water

et al. 2022

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Enteric viruses are common waterborne pathogens found in environmental water bodies contaminated with either raw or partially treated sewage discharge. Examples of these viruses include adenovirus, rotavirus, noroviruses, and other caliciviruses and enteroviruses like coxsackievirus and polioviruses. They have been linked with gastroenteritis, while some enteric viruses have also been implicated in more severe infections such as encephalitis, meningitis, hepatitis (hepatitis A and E viruses), cancer (polyomavirus), and myocarditis (enteroviruses). Therefore, this review presents information on the occurrence of enteric viruses of public health importance, diseases associated with human exposure to enteric viruses, assessment of their presence in contaminated water, and their removal in water and wastewater sources. In order to prevent illnesses associated with human exposure to viral contaminated water, we suggest the regular viral monitoring of treated wastewater before discharging it into the environment. Furthermore, we highlight the need for more research to focus on the development of more holistic disinfection methods that will inactivate waterborne viruses in municipal wastewater discharges, as this is highly needed to curtail the public health effects of human exposure to contaminated water. Moreover, such a method must be devoid of disinfection by-products that have mutagenic and carcinogenic potential.

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Section: Enteric Viruses Of Public Health Importancementioning

confidence: 99%

Section: Enteric Viruses Of Public Health Importancementioning

confidence: 99%

Section: Enteric Viruses Of Public Health Importancementioning

confidence: 99%

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Global public health implications of human exposure to viral contaminated water

et al. 2022

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“…Aichivirus consists of Human AiV (HAiV) 1, Murine Kobuvirus (MuKV) 1, and Canine Kobuvirus (CaKV) 1. Human AiV is composed of three genotypes (A-C; Yamashita et al, 2000;Shaheen et al, 2020;Kebe et al, 2021), and the infection rate of AiV in gastroenteritis cases worldwide is low between 0.4 and 6.5% (Rivadulla and Romalde, 2020;Taghinejad et al, 2020;Upfold et al, 2021). However, specific antibodies produced against the virus are found in about 80-90% of adults (Kitajima and Gerba, 2015;Rivadulla and Romalde, 2020), which is a pointer to the asymptomatic condition of most infections (Bergallo et al, 2017).…”

Section: Aichivirusmentioning

confidence: 99%

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Whole genome sequencing and genome characterization of Aichivirus isolated from Korean adults

Woo,

Hossain,

Jung

et al. 2024

Journal of Medical Virology

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The whole‐genome sequence (WGS) analysis of Aichivirus (AiV) identified in Korea was performed in this study. Using Sanger and Nanopore sequencing, the 8228‐nucleotide‐long genomic sequence of AiV (OQ121963) was determined and confirmed to belong to genotype A. The full‐length genome of OQ121963 consisted of a 7296 nt open reading frame (ORF) that encodes a single polyprotein, and 5′ UTR (676 nt) and 3′ UTR (256 nt) at 5′ and 3′ ends, respectively. The ORF consisted of leader protein (L), structural protein P1 (VP0, VP1, and VP3), and nonstructural protein P2 (2A, 2B, and 2C) and P3 (3A, 3B, 3C, and 3D). The secondary structure analysis of the 5′ UTR identified only stem‐loop C (SL–C) and not SL–A and SL–B. The variable region of the AiV genome was analyzed by MegAlign Pro and reconfirmed by SimPlot analysis using 16 AiV whole genomes known to date. Among the entire regions, structural protein region P1 showed the lowest amino acid identity (96.07%) with reference sequence AB040749 (originated in Japan; genotype A), while the highest amino acid identity (98.26%) was confirmed in the 3D region among nonstructural protein region P2 and P3. Moreover, phylogenetic analysis of the WGS of OQ121963 showed the highest homology (96.96%) with JX564249 (originated in Taiwan; genotype A) and lowest homology (90.14%) with DQ028632 (originated in Brazil; genotype B). Therefore, the complete genome characterization of OQ121963 and phylogenetic analysis of the AiV conducted in this study provide useful information allowing to improve diagnostic tools and epidemiological studies of AiVs.

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Prevalence and Genetic Diversity of <b><i>Aichi Virus 1</i></b> from Urban Wastewater in Senegal

Cited by 8 publications

References 39 publications

Global public health implications of human exposure to viral contaminated water

Global public health implications of human exposure to viral contaminated water

Table_1.docx

Whole genome sequencing and genome characterization of Aichivirus isolated from Korean adults

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