Prevalence and impact of acute kidney injury in hospitalized pediatric patients with acute pancreatitis

Thavamani, Aravind; Umapathi, Krishna Kishore; Sankararaman, Senthilkumar

doi:10.1007/s00467-021-05106-8

Cited by 2 publications

(4 citation statements)

References 19 publications

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“…Furthermore, inflammatory endotoxins and reactive oxygen species can directly act on the kidney to cause inflammation and a nephrotoxic effect [ 2 ]. In a recent study, the mortality rate among AP hospitalizations with AKI was 2.5%, and AKI almost doubled the risk of mortality among pediatric patients with AP [ 3 ]. AP as a cause of hemolytic uremic syndrome (HUS) is rare and reported in few case reports in both adults and pediatrics [ 4 , 5 ].…”

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confidence: 99%

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Concurrent acute kidney injury and pancreatitis in a female patient: Answers

et al. 2022

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confidence: 99%

“…In a recent study, the mortality rate among AP hospitalizations with AKI was 2.5%, and AKI almost doubled the risk of mortality among pediatric patients with AP [ 3 ].…”

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confidence: 99%

Concurrent acute kidney injury and pancreatitis in a female patient: Answers

et al. 2022

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“…Because the diagnosis and treatment of AP-related AKI involve a multidisciplinary approach, clinical intervention is more difficult and the prognosis of AKI is reduced. Acute kidney injury has become an independent risk factor for poor prognosis of AP, significantly prolonging the hospitalization time, and increasing costs and patient mortality 3,4 . There is currently no reliable biomarker to allow for early diagnosis or improve the outcomes of AKI patients.…”

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confidence: 99%

“…Acute kidney injury has become an independent risk factor for poor prognosis of AP, significantly prolonging the hospitalization time, and increasing costs and patient mortality. 3,4 There is currently no reliable biomarker to allow for early diagnosis or improve the outcomes of AKI patients.…”

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Establishment and Diagnostic Value of an Early Prediction Model for Acute Pancreatitis Complicated With Acute Kidney Injury

Chi,

Song,

et al. 2024

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Objectives To establish an early prediction model for acute pancreatitis (AP) complicated with acute kidney injury (AKI) and evaluate its diagnostic value. Method AP patients were recruited from the Emergency Department at Peking University People's Hospital in 2021 and stratified into AKI and control (no AKI) groups. Their clinical data were analyzed. The risk for AKI development was determined using logistic analyses to establish a risk prediction model, whose diagnostic value was analyzed using a receiver operating characteristic curve. Results There was no significant difference in the basic renal function between the AKI (n = 79) and control (n = 179) groups. The increased triglyceride glucose index (odds ratio [OR], 2.613; 95% confidence interval [CI], 1.324–5.158; P = 0.006), age (OR, 1.076; 95% CI, 1.016–1.140; P = 0.013), and procalcitonin (OR, 1.377; 95% CI, 1.096–1.730, P = 0.006) were associated with AKI development. A model was established for prediction of AKI (sensitivity 79.75%, specificity 96.65%). The area under the receiver operating characteristic curve was 0.856 which was superior to the Ranson, Bedside Index for Severity in AP, and Acute Physiology and Chronic Health Evaluation II scores (0.856 vs 0.691 vs 0.745 vs 0.705). Conclusions The prediction model based on age, triglyceride glucose, and procalcitonin is valuable for the prediction of AP-related AKI.

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Prevalence and impact of acute kidney injury in hospitalized pediatric patients with acute pancreatitis

Cited by 2 publications

References 19 publications

Concurrent acute kidney injury and pancreatitis in a female patient: Answers

Concurrent acute kidney injury and pancreatitis in a female patient: Answers

Establishment and Diagnostic Value of an Early Prediction Model for Acute Pancreatitis Complicated With Acute Kidney Injury

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