Prevalence and Impact of Post-traumatic Stress Disorder in Gastrointestinal Conditions: A Systematic Review

Exploring the Impact of Trauma and Psychosocial Processes on the Quality of Life in Individuals Living with Inflammatory Bowel Disease

“…Overall, the current study found that 32.2% of participants met a probable diagnosis for PTSD. This finding is consistent with the overall gastrointestinal inflammatory condition pooled prevalence rate of 31% reported in the systematic review by Glynn et al [14]. The current study found that 54.4% of individuals who met the criteria for a probable PTSD diagnosis reported IBD related trauma and 21 (30.9%) reported non IBD related trauma.…”

“…of PTSD by trauma type and identification of factors that contribute specifically to the development of IBD related trauma (e.g., diagnostic procedures, perceived support from treatment team). Recommendations for managing this screening process are outlined in the brief guide developed by Glynn et al [14]. Adopting an integrative approach is consistent with the national guidelines recommended by Crohn's & Colitis Australia that psychological screening should be conducted [50].…”

“…Further, living with a medical condition (such as IBD) is linked to the development of PTS [10][11][12][13], and subsequently, posttraumatic stress disorder (PTSD). In a recent systematic review, Glynn et al [14] identified that the prevalence of PTSD across gastrointestinal cohorts was high, with 31% of individuals with inflammatory conditions (e.g., ulcerative colitis, Crohn's disease, gastro-oesophageal reflux disease, peptic disease) having PTSD. Recent qualitative studies highlight multiple sources of trauma in IBD cohorts, including not only the physical and psychological impact of IBD, but also diagnostic and surgical processes, lack of perceived support from medical professionals, along with medication effectiveness and associated side effects [10,12].…”

Brain-gut axis dysfunction in the pathogenesis of traumatic brain injury

“…TBI induces a stress response that impacts the well-documented autonomic nervous system (ANS) control of GI function (5). Activation of the systemic immune system following TBI could play a major role in subsequent GI dysfunction, and the effects of TBI may be amplified further by psychological distress, which is known to exacerbate GI symptoms (6). Gut-to-brain communication is equally important, as sensory information arising from the gut lumen coordinates function across different regions of the gut.…”

Prevalence of Gastrointestinal Symptoms and Irritable Bowel Syndrome Among Individuals With Symptomatic Posttraumatic Stress Disorder

“…9 Although most studies have focused on childhood trauma and abuse, other studies support an association between gastrointestinal (GI) symptoms and trauma when trauma is experienced later in life. 9,10 For example, deployment to a war zone and combat exposure have been found to be associated with an increased risk of functional GI disorders, including IBS and functional dyspepsia. 4,11 Among the subset of individuals with trauma exposure who develop PTSD, epidemiologic studies indicate that PTSD and IBS are often comorbid, 12 especially among veterans [13][14][15] and an incident diagnosis of PTSD appears associated with an increased risk of developing IBS (standardized incidence ratio of 1.8 as compared with the general population).…”