2020
DOI: 10.34172/hpp.2020.18
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Prevalence and incidence of type 1 diabetes in the world: a systematic review and meta-analysis

Abstract: Background: Diabetes is referred to a group of diseases characterized by high glucose levels in blood. It is caused by a deficiency in the production or function of insulin or both, which can occur because of different reasons, resulting in protein and lipid metabolic disorders. The aim of this study was to systematically review the prevalence and incidence of type 1 diabetes in the world. Methods: A systematic search of resources was conducted to investigate the prevalence and incidence of type 1 diabetes in … Show more

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Cited by 506 publications
(355 citation statements)
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“…T1D is a metabolic disease characterized by the progressive decline of pancreatic β cells functions leading to relative or absolute insulin deficiency ( 7 ). T1D is one of the most frequent autoimmune disorders in the pediatric population, and its incidence and prevalence are increasing worldwide ( 8 ). It is estimated that about 18,000 children and adolescents are currently affected by T1D in Italy ( 9 ).…”
Section: Discussionmentioning
confidence: 99%
“…T1D is a metabolic disease characterized by the progressive decline of pancreatic β cells functions leading to relative or absolute insulin deficiency ( 7 ). T1D is one of the most frequent autoimmune disorders in the pediatric population, and its incidence and prevalence are increasing worldwide ( 8 ). It is estimated that about 18,000 children and adolescents are currently affected by T1D in Italy ( 9 ).…”
Section: Discussionmentioning
confidence: 99%
“…Currently, there are over 34.2 million people globally living with T1D, including over 500,000 people who are less than 15 years old [1,2]. Each year, 11.7 million people are diagnosed with T1D globally, while nearly 90,000 children are diagnosed worldwide [1][2][3]. Less than one-third of people living with T1D are consistently achieving target blood glucose levels in the range of 70-180 mg/dL [4].…”
Section: Introductionmentioning
confidence: 99%
“…The global AO and DM epidemic affects 2 billion people and 415 million people worldwide ( 1 , 2 ). Prevalence of both conditions continue to increase worldwide, resulting in a higher burden of cardiovascular (CV) diseases due to acceleration of atherosclerosis, endothelial dysfunction, and microvascular inflammation ( 3 , 4 ). Multiple observation studies have shown that AO and DM were associated with increased risk of heart failure (HF) manifestation regardless of other conventional CV risk factors ( 5 7 ).…”
Section: Introductionmentioning
confidence: 99%