“…That such patients were more likely to have culprit lesions in the posterior circulation is not surprising, as the difficulty in diagnosing MI involving the posterior circulation is well documented. Patients with posterior STEMI have been demonstrated to have increased mortality compared with those without evidence of posterior infarction, likely resulting at least in part from a delay in recognition as well as complications such as left ventricular dysfunction, mitral regurgitation, ventricular septal defect, or bradycardia, depending on the affected artery (19,20). In patients with left circumflex artery occlusion, the infarct may affect an electrocardiographically silent area of the heart, and the traditional 12-lead ECG may be entirely normal.…”