Prevalence and predictors of depression among dermatology clinic patients in a teaching hospital, Jeddah, Saudi Arabia

Mleeh, Nouf T; Alshamrani, Hussein M; Basyouni, Reem N; Alshehri, Khalid A; Algethami, Mohammed R.; Sehlo, Mohammad Gamal

doi:10.4103/jfmpc.jfmpc_399_19

Cited by 7 publications

(8 citation statements)

References 29 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Many previous studies have suggested the association between isotretinoin administration and depression, especially in patients that already suffer from depression. A previous study from Jeddah, Saudi Arabia showed that the prevalence of depression in their population was 15.8% [ 21 ]. This prevalence rate can be similar to the prevalence rate of depression among the general population [ 11 ].…”

Section: Discussionmentioning

confidence: 99%

Isotretinoin Use and Risk of Depression in Acne Vulgaris Patients in Riyadh, Saudi Arabia

AlGhofaili¹

2021

Cureus

View full text Add to dashboard Cite

Background The association between isotretinoin administration and depression in acne patients remains controversial. We aim to estimate the prevalence of depression among patients with acne vulgaris before and after treatment with isotretinoin in Riyadh, Saudi Arabia. Methods This was a prospective study on patients attending the King Khalid University Hospital (KKUH), a tertiary institution, who were prescribed isotretinoin for the treatment of acne vulgaris for the first time. The Beck Depression Inventory (BDI) was used to screen for depressive symptoms. Results A total of 179 patients were included in the study. The patients were then divided into two groups based on the treatment modality that they received: one group taking isotretinoin and the other treatment group who used other medications, including Retin-A (tretinoin) and Tazorac (tazarotene). A total of 119 patients were in the isotretinoin group with 91.6%, 2.5%, 1.7%, and 3.4% of those patients having a normal mood, mild depression, moderate depression, and severe depression scores before starting isotretinoin treatment, respectively. After three months of treatment, 94.1%, 1.7%, 0.8%, and 2.5% of patients had normal mood, mild depression, moderate depression, and severe depression, respectively. Meanwhile, after six months of treatment, 95.8%, 0.8%, 0%, and 1.7% of patients had normal mood, mild depression, moderate depression, and severe depression, respectively. The mean BDI score at the baseline was 3.31 ± 6.98 for isotretinoin and 3.17 ± 6.27 for other treatments. Compared to the baseline, patients using the isotretinoin showed a significant reduction in depression scores at three months (2.64 ± 6.17; p-value < 0.001), six months (1.99 ± 5.08; p-value < 0.001), and across all follow-up points (p-value < 0.001). Similar results were also estimated for the other treatment group, including Retin-A (tretinoin), adapalene, benzoyl peroxide, and doxycycline; however, no significant difference was noticed between the two groups (p-value = 0.885). Conclusion Isotretinoin treatment for acne does not appear to be associated with a statistically significant increased risk of depression in our population. Therefore, more studies are needed to understand this reflection in Saudi Arabia.

show abstract

Section: Discussionmentioning

confidence: 99%

Isotretinoin Use and Risk of Depression in Acne Vulgaris Patients in Riyadh, Saudi Arabia

AlGhofaili¹

2021

Cureus

View full text Add to dashboard Cite

show abstract

“…The local score for each anatomical area is generated by multiplying the given factor by the points of the most severe lesion within an area. The local scores are summed to obtain the total GAGS score, which categorizes acne severity into no acne (0 points), mild acne (1)(2)(3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18), moderate acne (19)(20)(21)(22)(23)(24)(25)(26)(27)(28)(29)(30), severe acne (31)(32)(33)(34)(35)(36)(37)(38), and very severe acne (≥39). 11…”

Section: Acne Gradingmentioning

confidence: 99%

“…6 Anxiety and depressive symptoms were more prevalent among patients with dermatological disease (39.5% in psoriasis and 30.2% in acne). 7 Many studies showed high prevalence rates of depression and anxiety among patients with acne, reaching up to >40%, with suicidal cases in 6-7%. This is due to the increase in psychiatric comorbidities in chronic diseases.…”

Section: Introductionmentioning

confidence: 99%

Assessment of Anxiety and Depression in Patients with Acne Vulgaris in Medina: A Case-Control Study

Molla

Alrizqi²,

Alharbi³

et al. 2021

CCID

View full text Add to dashboard Cite

Purpose Acne vulgaris is a common dermatological disease in adolescents that show high prevalence rates of anxiety and depression that may lead to consequences that affect quality of life. This study aimed to assess and compare anxiety and depression in patients with acne and a control group and to determine their correlation with other demographic data. Patients and Methods This was a case-control study conducted in 2019 for 3 months at the derma-tology department of Ohud Hospital and two other private clinics in the Medina region of Saudi Arabia. For this study, 296 consecutive patients in the age group of 12 to 60 years who were diagnosed as having acne vulgaris were enrolled and matched with a control group. Data were collected through a self-administered questionnaire, including sociodemographic data and Hospital Anxiety and Depression Scale scores. Results We found no significant differences between the two groups regarding sex, age group, nationality, and educational level, but found a significant difference in marital status (p < 0.001). Most (62.5%) of the acne cases were moderate in severity. The overall anxiety score in the acne group was 7.68 ± 4.90, with a significant difference with the control group (p = 0.031), whereas the anxiety level and depression score showed no significant difference (p = 0.082 and p = 0.656, respectively). Moreover, a strong correlation was found between anxiety and depression in the acne group (r = 0.732, p < 0.001). Conclusion A positive correlation was found between the anxiety and depression scores in the patients with acne, which was not related to age group or educational level. However, the anxiety scores of the patients with acne showed a significant relationship with sex.

show abstract

“…Mleeh, Nouf T et al [12] reported that psychosocial valuation should be defined when evaluating and treating psoriasis as it may help in reducing exacerbation of symptoms, mainly for conditions aggravated by stress. Bhutto A, M, et al [13] reported that; the age of children ranged from 8 months to 18 years (mean=11.27 years).…”

Section: Resultsmentioning

confidence: 99%

“…A meta-analysis study conducted in 2013 demonstrated that patients with psoriasis are 1.5 times more likely to exhibit depressive signs and symptoms compared to their healthy peers [25]. Mleeh, Nouf T et al [12] had demonstrated that; depression was the most prevalent psychological disorder among patients with psoriasis in Saudi Arabia (39.5%, P < 0.001). Kimball et al, it was concluded that a psychological burden resulting from psoriasis could be due to stress, stigmatization, depression, difficulty getting a job, and physical limitation [26].…”

Section: Discussionmentioning

confidence: 99%

Prevalence, Co-morbidities and Management of Psoriasis in Saudi Arabia: A Review

Alenazy

Alenazy²,

Alanazi³

et al. 2021

JPRI

View full text Add to dashboard Cite

Background: Psoriasis is a chronic inflammatory skin illness with an autoimmune pathogenic mannerisms and genetic tendency. It is regarded as erythematous plaques sheltered with silvery scales predominantly over the extensor exteriors, scalp, and lumbosacral region. The prevalence in Saudi Arabia was projected to be 5.3% (53% of psoriasis patients develop it before 30 years of age. Aim: The main objective of this study is to summarize the current evidence regarding prevalence, types, risk factors, associated comorbidities and management of psoriasis in Saudi Arabia. Methods: This is a systematic review was carried out, including PubMed, Google Scholar, and EBSCO that examining previous studies regarding psoriasis in KSA. Authors extracted the data, and then the author's names, year and region of publication, the study type, period of study, and the result were reported. Results: The review included 7 studies that illustrate prevalence, types, risk factors, associated comorbidities and management of psoriasis in Saudi Arabia. Conclusion: The incidence of psoriasis in Saudi Arabia is within previously reported figures worldwide. Family history seems to have a strong association with the occurrence of psoriasis. CVD and psychological disorders seem to be prevalent Saudi psoriatic patients. Topical medications are widely used and effective in psoriasis management in Saudi Arabia.

show abstract

Prevalence and predictors of depression among dermatology clinic patients in a teaching hospital, Jeddah, Saudi Arabia

Cited by 7 publications

References 29 publications

Isotretinoin Use and Risk of Depression in Acne Vulgaris Patients in Riyadh, Saudi Arabia

Isotretinoin Use and Risk of Depression in Acne Vulgaris Patients in Riyadh, Saudi Arabia

Assessment of Anxiety and Depression in Patients with Acne Vulgaris in Medina: A Case-Control Study

Prevalence, Co-morbidities and Management of Psoriasis in Saudi Arabia: A Review

Contact Info

Product

Resources

About