Prevalence and predictors of self-medication practices in the population of Saudi Arabia: systematic review ‎

Aldossary, Khlood

doi:10.51847/nlsc28kajo

Cited by 5 publications

(6 citation statements)

References 10 publications

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“…In our study, the two most widely used medicines in self-medication were cold remedies and sedatives, which were used by about 33% of the students. However, in addition to these two medications, most studies carried out in Iran, Turkey, Saudi Arabia, Finland and Spain also show that analgesics and antibiotics are also used frequently for self-medication [ 14 , 23 , 24 ]. This result indicates similarity in the use of medications that people use for self-medication.…”

Section: Discussionmentioning

confidence: 99%

Self-medication practices and their characteristics among Iranian university students

Rahimisadegh

Sharifi

Jahromi

et al. 2022

BMC Pharmacol Toxicol

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Background Self-medication in students, as educated people, is one of the most important health issues. It is known that inappropriate self-medication is harmful for individuals as it has potential risks, disrupts the drug market and increases the per capita financial drug consumption. Thus, the aim of this study is to investigate the habits related to drug use and the prevalence of self-medication practices among university students. Methods This cross-sectional study was conducted in 2021 at Jahrom universities/Iran, using an electronic “self-medication practices and medication habits” questionnaire. A total of 848 students from four healthcare and non-healthcare universities participated in the study. Results The prevalence of self-medication among students was 44.8%. The most common medicines used for self-medication included cold remedies and sedatives that were used by 33% of the students. About 47% of students stated that they have used antibiotics without a physician’s prescription. The internet and social networks were the source of information on self-medication in about 40% of students. There was no significant difference in self-medication between medical and non-medical students (OR = 0.865, 95% CI: 0.659–1.134). Self-medication in students with underlying disease was higher than students without underlying disease (OR = 2.8, 95% CI: 1.39–5.60). Conclusions Self-medication had a high prevalence among students. The best strategy to reduce or eliminate self-medication is to raise students’ awareness and knowledge about potential risk of self-medication practices.

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Section: Discussionmentioning

confidence: 99%

Self-medication practices and their characteristics among Iranian university students

Rahimisadegh

Sharifi

Jahromi

et al. 2022

BMC Pharmacol Toxicol

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“…According to the rotterdam criteria, the community prevalence of poly cystic ovaries in girls between the ages of 18 and 30 in our study was 18.9%, which is higher than the prevalence of 16% found in alsosary et alstudy . 's conducted in Saudi Arabia [17]. However, it is lower than research conducted in madinah 2017 by alradadi et al (32%) [2].…”

Section: Discussionmentioning

confidence: 74%

Prevalence and Risk Factors of Polycystic Ovarian Syndrome PCOS: Cross-sectional Study

Mohmed

Aljuhaysh²,

Alonze³

et al. 2023

J. Pharm. Res. Int.

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Background: The most prevalent endocrine illness in women of reproductive age is polycystic ovarian disease. In this study, girls between the ages of 18 and 30 who were vesiting the maternity hospital refer in King Saud, Saudi Arabia, will be assessed for poly cystic ovaries prevalence and risk factors. Methods: There were 1080 participants in this study, representing all outpatient visits over the chosen period (Jul 2022 to Jan 2023). They were required to answer questions about their menstrual cycle and the symptoms of hyperandrogenism on a questionnaire. Weight, height, waist, and hip circumferences were measured anthropometrically. Blood pressure was measured. A girl who exhibits either hirsutism or irregular menstruation, or both, was considered a probable case. All of the likely instances were required to undergo thorough examinations, hormone estimations, and ovarian ultrasounds. Results: Among the 1080 girls, 191 (17.6%) had irregular menstrual cycles, and 75 (6.9%) had hirsutism. According to Rotterdam's criteria, the prevalence of polycystic ovaries was found to be 18.9% after hormonal testing and ultrasound. The non-vegetarian diet, socioeconomic level I and II, snacking, obesity, insufficient physical activity, prehypertension, hypertension, central obesity, and self-reported emotional health issues in girls, and poly cystic ovaries in the family, were found to be substantially linked with polycystic ovaries. Conclusion: To lessen poly cystic ovaries and associated problems in females, early lifestyle change and health education were necessary.

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“…Aldossary et al. confirmed obesity as a risk factor for PCOS ( 34 ). Some studies dealt with the psychological burden among Saudi women with PCOS ( 35 , 36 ).…”

Section: Discussionmentioning

confidence: 99%

Molecular role of non-exonic variants in CALPAIN 10 gene in polycystic ovarian syndrome in Saudi women

Alageel,

Alshammary,

Ali Khan

2023

Front. Endocrinol.

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IntroductionNon-diabetic women with polycystic ovarian syndrome (PCOS) often have abnormal insulin regulation. Calpain 10 (CALP10) is a biomarker of type 2 diabetes mellitus, with some of its single-nucleotide polymorphisms (SNPs) influencing PCOS development.MethodsIn this case-control study on 90 women each with and without PCOS, we explored the molecular role of five CALP10 SNPs using biochemical parameters and Sanger sequencing analyses.ResultsDifferent genetic models, genotypes, and allele frequencies were significantly associated with UCSNP-19 (rs3842570; p=0.01), UCSNP-44 (rs2975760; p=0.009), UCSNP-56 (rs2975762; p<0.0001), and UCSNP-63 (rs5030952; p=0.0003) in women with PCOS. The multiple logistic regression model showed a strong association of CALP10 SNPs with fasting blood glucose (p<0.001). ANOVA showed significant associations with various biochemical parameters such as FSH (p=0.0001) in UCSNP-19 (rs3842570), FI (p=0.002), TG (p=0.01) in UCSNP-56 (rs2975762) and FBG (p=0.001), FI (p=0.004), FSH (p=0.02) & LDLc (p=0.04) in UCSNP-63 (rs5030952) SNPs. Haplotype analysis also revealed significant associations between different combinations of alleles in the studied 5 SNPs in women with PCOS (p<0.05). Generalized multifactor dimensionality reduction analysis showed the best gene–gene interactions among the five SNPs in CALP10I (p<0.05). However, dendrogram and graphical depletion models found no strong association in women with PCOS.ConclusionIn conclusion, this study confirms rs3842570, rs2975760, rs2975767, and rs5030952 SNPs in CALP10 gene is associated in diagnosed PCOS women in the Saudi Arabia.

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Prevalence and predictors of self-medication practices in the population of Saudi Arabia: systematic review ‎

Cited by 5 publications

References 10 publications

Self-medication practices and their characteristics among Iranian university students

Self-medication practices and their characteristics among Iranian university students

Prevalence and Risk Factors of Polycystic Ovarian Syndrome PCOS: Cross-sectional Study

Molecular role of non-exonic variants in CALPAIN 10 gene in polycystic ovarian syndrome in Saudi women

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