“…After pooling these studies, widowed and never-married subjects were at a significantly higher risk for depression than married subjects (OR 1.49, 95% CI 1.19, 1.87, P = 0.0006; OR 1.32, 95% CI 1.12, 1.55, P = 0.0007 respectively), and subjects who were divorced had a non-significantly higher risk for depression than those who were married (OR 1.23, 95% CI 0.57, 2.65). Of the 24 cross-sectional studies, two, five and two studies compared the risk for depression between widowed and divorced subjects, 31,41 between widowed and nevermarried subjects, 31,41,43,46,48 and between divorced and never-married subjects. 31,41 Pooling these studies, widowed subjects had a higher risk for depression than those who had never married (OR 1.51, 95% CI 1.14, 1.98, P = 0.004).…”