Prevalence and risk factors for type 2 diabetes mellitus in the Chinese adult population: The InterASIA Study

Hu, Dongsheng; Sun, Liang; Fu, Pengyu; Xie, Jing; Lu, Jie; Zhou, Jing; Yu, Dahai; Whelton, Paul K.; He, Jiang; Gu, Dongfeng

doi:10.1016/j.diabres.2009.02.021

Cited by 47 publications

(37 citation statements)

References 33 publications

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“…This finding could be related to many influences such as genetic and ethnic factors, inactive lifestyles and incorrect dietary habits. Age-specific prevalence rates of diabetes in some neighbouring countries and also previous studies in the Islamic Republic of Iran are compared in Table 5 (8,(16)(17)(18)(19)(20). As the table shows, the prevalence of diabetes in Yazd is greater than the average national level in Islamic Republic of Iran and those of the nearby countries.…”

Section: Discussionmentioning

confidence: 93%

Prevalence and risk factors of diabetes mellitus in a central district in Islamic Republic of Iran: a population-based study on adults aged 40–80 years

Katibeh

Hosseini

Soleimanizad

et al. 2015

Easter Mediterr Health J

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Previous studies on type 2 diabetes mellitus in the Islamic Republic of Iran were mainly performed in provinces with large populations. This study determined the prevalence and risk factors of diabetes mellitus in an adult population (40-80 years old) from Yazd district. Multistage, systematic cluster random sampling was used in a crosssectional, population-based survey. Demographic, clinical and anthropometric data were collected, with diabetes defined as fasting blood sugar ≥ 7 mmol/L or a positive medical history of diabetes. The age-and sex-standardized prevalence of diabetes in 2090 individuals participants was 24.5% (95% CI: 22.2-26.8%), including 10.5% new cases. For each year of ageing, the prevalence of diabetes increased significantly by 4% and this trend was more pronounced in females than males. Low education and hypertension were significantly associated with diabetes prevalence. The prevalence of diabetes mellitus in Yazd is greater than the average levels nationwide and those of nearby countries. ‫ـكانية‬ ‫سـ‬ ‫ـة‬

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Section: Discussionmentioning

confidence: 93%

Prevalence and risk factors of diabetes mellitus in a central district in Islamic Republic of Iran: a population-based study on adults aged 40–80 years

Katibeh

Hosseini

Soleimanizad

et al. 2015

Easter Mediterr Health J

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“…31 In contrast, another study in China found that the prevalence of diabetes was generally unaffected by educational level but was higher in the high-income group. 32 Moreover, studies from both developing and developed countries have found inverse associations between diabetes and educational level and household socioeconomic status, perhaps because the better-educated were more health-conscious. 19,[33][34][35] However, obesity appears to be an independent risk factor for diabetes and a study from Brazil showed that better-educated and wealthier individuals were more likely to be obese.…”

Section: Discussionmentioning

confidence: 99%

Prevalence of diabetes and prediabetes and their risk factors among Bangladeshi adults: a nationwide survey

Akter

Rahman

Abe

et al. 2014

Bull. World Health Organ.

288

260

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“…This may suggest that PD-MSC play an immunoregulatory role. It has been reported that among T2D patients, some of them may have latent autoimmune diabetes in adult (LADA) [2,6,26,40], whose anti-islet cell antibodies and anti-glutamic acid decarboxylase antibodies are positive due to a possible immune response. However, so far, there is no uniform standard for diagnosing the LADA, so we do not exclude these three cases.The mechanism of β-cell function's improvement after transplantation of PD-MSC remains unclear at present.…”

Section: Discussionmentioning

confidence: 99%

“…More than 92 million Chinese men and women have diabetes and 148 million have prediabetes, in which type 2 diabetes (T2D) accounts for more than 90% [1]. Diabetes can result in multi-system chronic complications, particularly micro-and macrovascular complications, with high morbidity and mortality [2][3][4]. The islet transplantation is an efficient therapy for T2D, especially for those who had a long duration, serious islet cell dysfunction, or poor blood glucose control even with large dose of insulin application.…”

Section: Introductionmentioning

confidence: 99%

Transplantation of placenta-derived mesenchymal stem cells in type 2 diabetes: a pilot study

et al. 2011

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Mesenchymal stem cells (MSC) have been used in clinical trials for severe diabetes, a chronic disease with high morbidity and mortality. Bone marrow is the traditional source of human MSC, but human term placenta appears to be an alternative and more readily available source. Here, the therapeutic effect of human placenta-derived MSC (PD-MSC) was studied in type 2 diabetes patients with longer duration, islet cell dysfunction, high insulin doses as well as poor glycemic control in order to evaluate the safety, efficacy and feasibility of PDMSC treatment in type 2 diabetes (T2D). Ten patients with T2D received three intravenous infusions of PDSC, with one month interval of infusion. The total number of PDSC for each patient was (1.22-1.51) × 10(6)/kg, with an average of 1.35 × 10(6)/kg. All of the patients were followed up after therapy for at least 3 months. A daily mean dose of insulin used in 10 patients was decreased from 63.7±18.7 to 34.7±13.4 IU (P<0.01), and the C-peptide level was increased from 4.1 ±3.7 ng/mL to 5.6 ±3.8 ng/mL (P<0.05) respectively after therapy. In 4 of 10 responders their insulin doses reduced more than 50% after infusion. The mean levels of insulin and C-peptide at each time point in a total of 10 patients was higher after treatment (P<0.05). No fever, chills, liver damage and other side effects were reported. The renal function and cardiac function were improved after infusion. The results obtained from this pilot clinical trial indicate that transplantation of PD-MSC represents a simple, safe and effective therapeutic approach for T2D patients with islet cell dysfunction. Further large-scale, randomized and well-controlled clinical studies will be required to substantiate these observations.

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Prevalence and risk factors for type 2 diabetes mellitus in the Chinese adult population: The InterASIA Study

Cited by 47 publications

References 33 publications

Prevalence and risk factors of diabetes mellitus in a central district in Islamic Republic of Iran: a population-based study on adults aged 40–80 years

Prevalence and risk factors of diabetes mellitus in a central district in Islamic Republic of Iran: a population-based study on adults aged 40–80 years

Prevalence of diabetes and prediabetes and their risk factors among Bangladeshi adults: a nationwide survey

Transplantation of placenta-derived mesenchymal stem cells in type 2 diabetes: a pilot study

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