Prevalence and Risk Factors for Peripheral Arterial Disease in Type 2 Diabetic Out Patients in A Care Center in Cotonou

Abstract

Aim: To determine the prevalence of peripheral arterial disease and its risk factors in type 2 diabetic outpatients. Materials and Methods: It was a descriptive and analytical cross-sectional study, which included 146 diabetic out patients seen. Peripheral arterial disease (PAD) has been accessed using Ankle-Brachial Index and Arterial Doppler Ultrasound . PAD was defined by an ABI value ≤ 0.9 in either of the legs Data management and analysis were performed using Epi-Info software. A p value <0.05 was considered significant. Results: The overall prevalence of peripheral arterial disease was 62.3%. Factors statistically associated with peripheral arterial disease were age (p=0.009), duration of diabetes greater than 10 years (p=0.006) and presence of peripheral neuropathy (p=0.0005). Conclusion: The prevalence of peripheral arterial disease is high in type 2 diabetic outpatients. A systematic screening and suitable management should be done in order to prevent cardiovascular events often associated.

The Association of Glycated Hemoglobin and Lipid Profile with Peripheral Artery Disease in Metabolic Syndrome Patients from Northwestern Algeria

“…In an Indian study, the prevalence was 36% in diabetics. A higher prevalence (62.3%) was estimated in diabetic patients by Gninkoun et al 20 .Recent results from the Bypass Angioplasty Revascularisation Investigation in type 2 diabetes (BARI 2D) study revealed that a 1% increase in HbA1c was associated with a 21% increased risk of PAD in type 2 diabetics 28 .Moussio et al, noted an increase in HbA1c levels in type 2 diabetics with PAD 29, 30 .Our findings highlighted higher levels of FBG, TC, TG and LDL in the presence of PAD We found a strong and significant positive association between HbA1c and FBG (r = 0.753, p<0.001) and a weak and significant positive correlation between Hba1c and TG (r = 0.288, p<0.001). However, a negative correlation was found with HDL (r= -0.356, p<0.001).…”