Prevalence and Risk Factors of Dry Eye Symptoms after Successful Dacryocystorhinostomy for Patients with Lacrimal Passage Obstruction

Abstract

Purpose To investigate the prevalence of dry eye symptoms after successful dacryocystorhinostomy and explore the potential risk factors. Methods: This cross-sectional study included 565 patients with lacrimal passage obstruction (LPO) who underwent external dacryocystorhinostomy. Ocular Surface Disease Index (OSDI) total score of 13 or more was regarded as presence of dry eye symptoms. OSDI total score greater than 22 combined with self-reported dry eye was defined as symptomatic dry eye. Logistic regression and linear regression were used to examine the associations between OSDI scores and its potentially predictive factors. Results: Of the 565 patients, 344 completed the questionnaire, among which 101(29.4%) patients presented with dry eye symptoms, including 53(15.4%) mild, 14(4.1%) moderate and 34(9.9%) severe, and 48(14.0%) patients can be defined as symptomatic dry eye. Univariate logistic regression revealed that age, educational levels, income levels, and hypertension were significantly correlated with the presence of dry eye symptoms ( P < 0.05). After multivariate adjustment, lower income levels were found significantly associated with dry eye symptoms ( P < 0.05). Univariate linear regression demonstrated that age, lower educational levels, surgery history, and hypertension were significantly associated with OSDI total score ( P = 0.037, 0.012, 0.022, 0.029 respectively). Multivariate stepwise linear regression manifested that educational levels and the surgery history influenced the OSDI total score mostly ( P = 0.021, 0.036 respectively). Conclusions: Dry eye problem of LPO patients after successful dacryocystorhinostomy cannot be ignored. In the preoperative evaluation, we should pay special attention to the elderly patients with lower educational levels, lower income levels or systemic diseases.

Higher incidence of meibomian gland dysfunction in postmenopausal women with primary acquired nasolacrimal duct obstruction

“…The OSDI score (33.33 [18.92, 53.04]) was considerably higher in the PANDO group than in the control group (13.89 [2.78, 25.00]) ( p < 0.001). The MG loss score was higher in the PANDO group (3 [ 2 , 4 ]) than in the control group (2 [ 2 , 3 ]) ( p = 0.004). The eyelid margin score was higher in the PANDO group (3 [ 2 , 4 ]) than in the control group (2 [ 1 , 3 ]), (< 0.001).…”

“…The MG loss score was higher in the PANDO group (3 [ 2 , 4 ]) than in the control group (2 [ 2 , 3 ]) ( p = 0.004). The eyelid margin score was higher in the PANDO group (3 [ 2 , 4 ]) than in the control group (2 [ 1 , 3 ]), (< 0.001). There was no significant difference in the CFS score, MG expressibility score, or meibum quality score between the PANDO group and the control group (Table 2 ).…”

“…Previous research has found that nearly 20–27% of patients with PANDO experience dry eye postoperatively and have no better or worse quality of life [ 3 , 4 ]. However, whether patients with PANDO already had dry eyes before surgery was unclear.…”

Prevalence and risk factors for depression and anxiety in patients with nasolacrimal duct obstruction

“…However, for patients with NLDO, they may still face a variety of physical and mental health problems after treatment. For example, dry eye symptoms may worsen after the improvement of epiphora, which also affects the patient’s quality of life ( 25 ). Incomplete improvement of epiphora symptoms and the appearance of dry eye symptoms, including accompanying skin irritation symptoms and social embarrassment, may have a negative effect on the quality of life and psychological state of patients, leading to the emergence of anxiety and depressive symptoms.…”

Morphometric Evaluation of the Lacrimal Sac Fossa in Anatolian Population Using Multidetector Computed Tomography

“…Otherwise, shrinkage of the mucosa, which is an expected alteration during the healing phase, might obstruct the bony window fully or partially, ultimately resulting in a blockage of tear flow to the nasal cavity (8). With a successful DCR, optimal patency of the nasolacrimal duct can be achieved by the removal of bony elements between the anterior and posterior lacrimal crests (9). Therefore, it should be considered that the variational morphology of this relatively small region might affect the outcomes of the DCR (10).…”