Prevalence and risk factors of people at-risk of obstructive sleep apnea in a rural community of Odisha, India: a community based cross-sectional study

Choudhury, Anurag; Routray, Dipanweeta; Swain, Santosh Kumar; Das, Aswin Kumar

doi:10.1016/j.sleep.2019.03.014

Cited by 16 publications

(9 citation statements)

References 31 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Recent studies demonstrated that adherence to CPAP therapy is not the only factor for successful treatment; lifestyle behavior, physical activity, and a healthy diet improve its effects [ 31 ]. Alcohol consumption and smoking may play an essential role in OSA by increasing sleep disruption through pharyngeal resistance and airway inflammation [ 32 , 33 ]. Therefore, smoking cessation and control of alcohol drinking prevent the risk of airway collapsibility during sleep.…”

Section: Discussionmentioning

confidence: 99%

CPAP Therapy on Depressive and Anxiety Symptoms in Patients with Moderate to Severe Obstructive Sleep Apnea Syndrome

et al. 2022

View full text Add to dashboard Cite

Backgrounds and Objectives: There is a link between sleep apnea syndrome (OSA) and depressive and anxiety symptoms, but the underlying mechanisms are not fully understood. The study aimed to determine the prevalence of these symptoms in patients with OSA and to evaluate the impact of continuous positive airway pressure (CPAP) on depression and anxiety scores. Materials and Methods: Ninety-nine consecutive new patients diagnosed with moderate or severe (apnea-hypopnea index AHI ≥ 15 events/h) OSA were accepted for the CPAP therapy. Patients completed a patient health questionnaire (PHQ-9) for depressive symptoms and a generalized anxiety questionnaire (GAD-7) for anxiety symptoms before the CPAP treatment, after 6 months, and after 1 year of CPAP therapy with compliance. For both scores (PHQ-9 and GAD-7), a cut point ≥10 was used to indicate the presence of clinically depressive and anxiety symptoms. Results: Forty-eight individuals (48.48%) had PHQ-9 scores above the cut-off point ≥ 10, and twenty-seven participants (27.27%) had GAD-7 scores above the cut-off point ≥10. A significant correlation has been shown between PHQ-9 score and BMI (p < 0.0001), AHI (p < 0.0001), ODI (p < 0.001), ESS (p < 0.001), GAD-7 score (p < 0.0001), and [t90] (p < 0.0001), while GAD-7 was correlated with AHI (p < 0.030), ODI (p < 0.006), and [t90] (p < 0.001). The PHQ-9 and GAD-7 scores decreased significantly after 6 months of CPAP therapy in all groups and after 1 year of CPAP use. Conclusions: OSA patients should be screened for depression and anxiety. Furthermore, CPAP should be the first choice of treatment before starting other treatments for depression and anxiety symptoms.

show abstract

Section: Discussionmentioning

confidence: 99%

CPAP Therapy on Depressive and Anxiety Symptoms in Patients with Moderate to Severe Obstructive Sleep Apnea Syndrome

et al. 2022

View full text Add to dashboard Cite

show abstract

“…Studies consistently reported several risk factors contributing to OSA. These include: age > 35 years (OR = 4.5, 95% CI, 1.4 to 13.8) [ 23 ]; BMI ≥ 25 kg/m 2 (aOR = 3.5, 95% CI, 1.2 to 10.5) [ 24 ]; alcoholism (aOR = 4.5, 95% CI, 1.8 to 11.1) [ 24 ]; higher Epworth sleepiness scale (ESS) (OR: 1.19, 95% CI 1.07 to 1.31) [ 29 ]; mean apnea duration (OR: 1.07, 95% CI 1.03 to 1.11) [ 29 ]; oxygen desaturation index (ODI) (OR: 1.06, 95% CI 1.03 to 1.10) [ 29 ]; and nocturnal oxygen desaturation (NOD) (OR: 2.44, 95% CI 1.17 to 5.09) [ 29 ]. Severe OSA (AHI ≥ 30) was significantly associated with excessive daytime sleepiness (OR, 20.27; 95% CI, 1.58 to 26.97) and oxygen desaturation index (OR, 4.05; 95% CI, 1.86 to 8.81) [ 34 ].…”

Section: Resultsmentioning

confidence: 99%

“… Score = 2; moderate; study design = 1 robust analyses = 1; others = 0. Choudhury et al, 2019 [ 24 ] India Community based cross-sectional study 200 Hypertension, obesity Patients with high risk of OSA, snoring was reported by 70%, excessive daytime sleepiness by 50%, 28% were smokers and 48% reported alcohol use. The associated risk factors were age > 35 years (OR = 4.5, 95% CI, 1.4 to 13.8), BMI ≥ 25 kg/m 2 (aOR = 3.5, 95% CI, 1.2 to 10.5), alcoholism (aOR = 4.5, 95% CI, 1.8 to 11.1), and hypertension (aOR = 11.5, 95% CI, 4.7 to 28.0).…”

Section: Methodsmentioning

confidence: 99%

Association and Risk Factors for Obstructive Sleep Apnea and Cardiovascular Diseases: A Systematic Review

2021

View full text Add to dashboard Cite

Obstructive sleep apnea (OSA) is a serious, potentially life-threatening condition. Epidemiologic studies show that sleep apnea increases cardiovascular diseases risk factors including hypertension, obesity, and diabetes mellitus. OSA is also responsible for serious illnesses such as congestive heart failure, stroke, arrhythmias, and bronchial asthma. The aim of this systematic review is to evaluate evidence for the association between OSA and cardiovascular disease morbidities and identify risk factors for the conditions. In a review of 34 studies conducted in 28 countries with a sample of 37,599 people, several comorbidities were identified in patients with severe OSA—these were: heart disease, stroke, kidney disease, asthma, COPD, acute heart failure, chronic heart failure, hyperlipidemia, thyroid disease, cerebral infarct or embolism, myocardial infarction, and psychological comorbidities including stress and depression. Important risk factors contributing to OSA included: age > 35 years; BMI ≥ 25 kg/m2; alcoholism; higher Epworth sleepiness scale (ESS); mean apnea duration; oxygen desaturation index (ODI); and nocturnal oxygen desaturation (NOD). Severe OSA (AHI ≥ 30) was significantly associated with excessive daytime sleepiness and oxygen desaturation index. The risk of OSA and associated disease morbidities can be reduced by controlling overweight/obesity, alcoholism, smoking, hypertension, diabetes mellitus, and hyperlipidemia.

show abstract

“…In addition, smoking-related airway inflammation and disease may increase vulnerability to OSA [ 4 ]. Alcohol ingestion has been demonstrated to acutely increase nasal and pharyngeal resistance in awake subjects with increased number and duration of hypopnea and apnea events; administration of alcohol near bedtime could imply an adverse acute impact on breathing during sleep [ 4 , 11 ]. Hence, the control of smoking and alcohol drinking is of great significance for the prevention of OSA.…”

Section: Discussionmentioning

confidence: 99%

Association of healthy lifestyle with risk of obstructive sleep apnea: a cross-sectional study

et al. 2022

View full text Add to dashboard Cite

Background No studies investigated the whole effect of modifiable lifestyle factors on OSA risk. This study aimed to examine the individual and combined effects of lifestyle factors on OSA risk among Chinese adults. Methods This cross-sectional study included 9733 participants aged 35 to 74 years from the baseline survey of Guangzhou Heart Study. OSA was evaluated by Berlin Questionnaire. The healthy lifestyle score (HLS), representing the overall effect of lifestyles, was derived from seven lifestyle factors: active smoking, passive smoking, alcohol, diet, waist-hip ratio, leisure-time physical activity, and mental status. Odds ratio (OR) with 95% confidence interval (CI) was calculated using the multivariate logistic regression model. Results 8107 participants were divided into the non-OSA group and 1626 participants into the OSA group. No passive smoking (OR 0.83, 95% CI 0.74–0.94), healthy waist-hip ratio (OR 0.67, 95% CI 0.58–0.77) and healthy mental status (OR 0.45, 95% CI 0. 29–0.73) were associated with a reduced risk of OSA after adjusting for confounders, while others not. Participants with higher HLS were negatively associated with OSA risk (P-trend < 0.001). In comparison to the participants with 0–3 HLS, the OR for participants with 4, 5, 6, and 7 HLS was 0.68 (95% CI 0.56–0.84), 0.71 (95% CI 0.59–0.86), 0.62 (95% CI 0.51–0.76) and 0.49 (95% CI 0.37–0.65) after adjusting for confounders. Every 1-score increment of HLS was associated with a 13% lower risk of OSA. Conclusions The results suggest that HLS reflecting the combined effect of multiple-dimensional lifestyle factors was inversely associated with OSA risk. Preventive strategies integrating multiple lifestyle factors may provide a more feasible approach for OSA prevention.

show abstract

Prevalence and risk factors of people at-risk of obstructive sleep apnea in a rural community of Odisha, India: a community based cross-sectional study

Cited by 16 publications

References 31 publications

CPAP Therapy on Depressive and Anxiety Symptoms in Patients with Moderate to Severe Obstructive Sleep Apnea Syndrome

CPAP Therapy on Depressive and Anxiety Symptoms in Patients with Moderate to Severe Obstructive Sleep Apnea Syndrome

Association and Risk Factors for Obstructive Sleep Apnea and Cardiovascular Diseases: A Systematic Review

Association of healthy lifestyle with risk of obstructive sleep apnea: a cross-sectional study

Contact Info

Product

Resources

About