Prevalence and risk factors of actinic keratosis in patients attending Italian dermatology clinics

Fargnoli, Maria Concetta; Altomare, G. F.; Benati, Elisa; Borgia, Francesco; Broganelli, Paolo; Carbone, Anna; Chimenti, Sergio; Donato, Sergio; Girolomoni, Giampiero; Micali, Giuseppe; Moggio, Erica; Parodi, Aurora; Piaserico, Stefano; Pistone, Giuseppe; Potenza, Concetta; Puviani, Mario; Raucci, Margherita; Vaccari, Sabina; Veglio, Stefano; Zanca, Andrea; Peris, Ketty

doi:10.1684/ejd.2017.3126

Cited by 36 publications

(35 citation statements)

References 36 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…ese results partially agree with those reported by Flohil et al [15] in the Rotterdam Study and Fargnoli et al [16] in Italy who found a significant association of AKs with male gender, light pigmentation status (based on eye, hair, and skin color), skin wrinkling, older age, and having between 25-50 nevi and facial solar lentigos, among others. However, accoding to the multivariate analysis, the most relevant factor was the place of the ski resort, something which agrees with the fact that keratinocyte cancer incidence is directly correlated with latitude, either in general population or in UV-exposed workers [17].…”

Section: Discussionsupporting

confidence: 91%

Skin Cancer Prevalence in Outdoor Workers of Ski Resorts

Gilaberte

Casanova

García‐Malinis

et al. 2020

Journal of Skin Cancer

View full text Add to dashboard Cite

Background. Snow reflectivity and altitude increase the exposure of ski resort workers to solar ultraviolet radiation. The aim was to assess the presence of skin cancer in ski resorts workers and compare it with other groups of outdoor workers reviewing published studies. Methods. An observational cross-sectional prospective study was conducted in the three largest ski resorts in Spain: Baqueira Beret, Lleida; Formigal, Huesca and Sierra Nevada, Granada. All outdoor workers including ski instructors were invited to participate in the study. The participants completed a validated questionnaire about sun exposure and underwent a skin examination. Results. 219 workers were included in the study (80% male; mean age 43.8 (SD 11.31) years). Actinic keratosis (AK) but no other skin cancers were detected in 32 participants (14.62%). Those with AK worked in the Southernmost ski resort, were more likely to have light colour hair, and were older and with higher photoaging grade than those without them. Conclusion. Compared to other studies, outdoor workers on ski resorts show a higher prevalence of AK than general population but a lower prevalence than other groups of outdoor workers.

show abstract

Section: Discussionsupporting

confidence: 91%

Skin Cancer Prevalence in Outdoor Workers of Ski Resorts

Gilaberte

Casanova

García‐Malinis

et al. 2020

Journal of Skin Cancer

View full text Add to dashboard Cite

show abstract

“…The findings of this study were not influenced by sex or age and are in agreement with those described in previous studies 13,14 . Szeimies et al 15 also used the same secondary outcomes as Olsen et al 16 in the treatment of grade I and II AKs.…”

Section: Discussionsupporting

confidence: 91%

Peeling with 70% glicolic acid followed by 5% 5‐fluorouracil as well as 5% 5‐fluorouracil cream are effective methods for the treatment of actinic keratoses on upper limbs: A randomized clinical trial

Heuser

Casagrande

et al. 2020

Dermatologic Therapy

View full text Add to dashboard Cite

The 5% 5‐fluorouracil (5‐FU) cream, considered the gold standard topical treatment, and peeling using 70% glycolic acid (GA) followed by 5% 5‐FU are methods for the treatment of actinic keratoses (AKs). However, the comparison of these two treatments had not yet been described and therefore was the objective of this study. A randomized clinical trial, intrapatient study in which 17 patients received a type of treatment in the right and left upper limb with 5% 5‐FU cream (twice daily) or a peeling application of 70% GA (every 15 days) followed by 5% 5‐FU cream. There was a significant reduction of 75% and 85.71% in the mean number of AK lesions and of 74.5% and 85.71% in the size of lesions on the upper limbs of patients treated with peeling and 5% 5‐FU cream (P‐value ≤.001), respectively. Neither treatment was superior to the other since there was no significant difference (P‐value ≥.05) between the treatments, both at the post‐intervention period as well as when comparing the difference between the pre and post‐intervention periods. The peeling with 70% GA followed by 5% 5‐FU as well as 5% 5‐FU cream are effective methods for the treatment of AKs on upper limbs.

show abstract

“…These data were also confirmed by Trakatelli et al [23], who, in a large European case-control study, showed that outdoor workers used less sunscreen and were more exposed to UV rays during work and free time. Similar results were recently confirmed also in a population attending Italian dermatology clinics, showing an odds ratio of 1.9 (1.4-2.4) in people working outdoors more than six hours/day [57]. These observations are in line with the detection of signs of significant photodamage in outdoor workers.…”

Section: Discussionsupporting

confidence: 85%

Non-Melanoma Skin Cancer in Outdoor Workers: A Study on Actinic Keratosis in Italian Navy Personnel

Vimercati

Maria

Caputi

et al. 2020

IJERPH

Self Cite

View full text Add to dashboard Cite

Occupational exposure to ultraviolet radiation is one of the main risk factors for non-melanoma skin cancer (NMSC) development. The most common variants of NMSC are basal cell carcinomas, squamous cell carcinomas, and actinic keratosis (AK). The latter is nowadays considered by most authors as an early squamous cell carcinoma rather than a precancerous lesion. Outdoor workers have a higher risk of developing NMSC because they spend most of the working day outside. The aim of this descriptive study was to assess the prevalence of skin lesions, especially AK, in a professional category of individuals exposed to ultraviolet (UV) radiation: the Italian Navy. From January to June 2016, a questionnaire and a total skin examination of 921 military personnel were administered by medical specialists (dermatologists) in seven different Italian Navy centres. AK was detected in 217 of 921 (23.5%) workers. Older age, outdoor occupation, longer working life, and fair skin seem to promote the development of AK. Of the 217 workers with AK, 187 (86.2%) had lesions in chronically sun-exposed skin areas. Italian Navy personnel have a high AK prevalence. Further studies are needed to investigate occupational hazards and their health effects among outdoor workers to promote protective behaviour and raise awareness of skin cancer.

show abstract

Prevalence and risk factors of actinic keratosis in patients attending Italian dermatology clinics

Cited by 36 publications

References 36 publications

Skin Cancer Prevalence in Outdoor Workers of Ski Resorts

Skin Cancer Prevalence in Outdoor Workers of Ski Resorts

Peeling with 70% glicolic acid followed by 5% 5‐fluorouracil as well as 5% 5‐fluorouracil cream are effective methods for the treatment of actinic keratoses on upper limbs: A randomized clinical trial

Non-Melanoma Skin Cancer in Outdoor Workers: A Study on Actinic Keratosis in Italian Navy Personnel

Contact Info

Product

Resources

About