Prevalence and Risk Factors of Gastritis in Shahdara and Associated Areas

Sharif, Saima; Maqbool, Rabia; Naz, Shagufta; Farasat, Tasnim

doi:10.54692/lgujls.2021.0501144

Cited by 2 publications

(1 citation statement)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…[7]. The prevalence of risk factors which will be estimated in the current study is very high, especially in Pakistan [8]. Stroke patients are being administered multiple drug therapy and are at risk of drug-related problems (DRPs), these DRPs are key determinants in this current study [9].…”

Section: Introductionmentioning

confidence: 89%

A prospective observational study of estimating drug related problems and clinical outcomes in subtypes of stroke patients

Ali,

Shoaib,

Nesar

et al. 2024

PLoS ONE

View full text Add to dashboard Cite

Background Stroke is a neurological disease and a leading cause of mortality worldwide. Strokes mainly consist of two types: hemorrhage and ischemia. Stroke patients are being administered multiple drug therapy and are at risk of drug-related problems. Aim To estimate drug-related problems (DRPs) and clinical end outcomes in hospitalized stroke patients. Methods Current study was a multicenter, cross-sectional prospective observational study including 250 stroke patients admitted to tertiary care hospitals in Karachi, Pakistan. The study included all clinical subtypes of stroke patients i.e. Stroke, Ischemic stroke, Hemorrhagic stroke, CVA, and TIA. Associations among patient-clinical end outcomes and drug therapy-related variables like DRPs, mortality, and morbidity rates were estimated using Pearson’s chi-squared test. Statistical analysis was done by using SPSS software, version 25. Results A total of 250 patients participated in this study suffering from different clinical subtypes of stroke i.e. Ischemic stroke, hemorrhagic stroke, TIA, and CVA, including 46% male and 54% female patients. The majority of patients’ stay at the hospital was between 1–10 days. The overall mortality rate in stroke patients was 51%. HAIs were observed in 70% of patients, HAIs faced by patients were SAP, CAP, UTI, sepsis, and VAP. Drugs were assessed according to NEML i.e. access group antibiotics, watch group antibiotics, reserve group antibiotics, statins, antiepileptics, and proton pump inhibitors. Majorly ceftriaxone was administered to 79% of patients, piperacillin-tazobactam to 52%, and cefixime to 48%, whereas meropenem was administered to 42% of patients along with vancomycin to 39% of total patients. A high mortality rate was observed in the case of Klebsiella pneumoniae and Staphylococcus aureus i.e. 78% and in the case of streptococcus pneumoniae 61% mortality rate was observed. Due to the presence of DRPs and various other clinical factors like comorbidities, DDIs, HAIs, administration of potentially nephrotoxic drugs, and administration of antibiotics without having CST, hospitalized stroke patients faced many problems. Conclusion This study helped determine DRPs along with various clinical factors affecting the clinical end outcomes of patients suffering from any clinical subtype of stroke. Due to the enhancement in the evidence of the incidence of DRPs in tertiary care hospitals, pharmacist-led drug therapy review by interfering with doctors and other medical professionals at the patient bed site is needed and should be done to avoid any negative end outcomes and serious issues related to DRPs.

show abstract

Section: Introductionmentioning

confidence: 89%

A prospective observational study of estimating drug related problems and clinical outcomes in subtypes of stroke patients

Ali,

Shoaib,

Nesar

et al. 2024

PLoS ONE

View full text Add to dashboard Cite

show abstract

Risk Factors Associated with Gastritis among Adult Patients Attending at Capital Hospital in Mogadishu- Somalia

Hassan Ahmed,

Mohamed Omer,

Hassan Mohamed

et al. 2024

International Journal of Innovative Science and Research Techno

View full text Add to dashboard Cite

Background: Gastritis, an inflammatory disorder affecting the lining of the stomach, is a prevalent health concern across the globe, particularly in developing regions like Somalia. This study aims to investigate the primary risk factors linked to gastritis among adults receiving care at Capital Hospital in Mogadishu.  Methods: An unmatched case-control study was executed from June 1 to July 30, 2024, involving 63 adult participants, with 21 patients diagnosed with gastritis through endoscopic procedures and 42 controls. A semi- structured questionnaire was employed to gather data on socio-demographic characteristics, dietary patterns, lifestyle habits, medical histories, and medication usage. Statistical analysis was performed using SPSS version 26.  Results: The investigation revealed a gastritis prevalence of 78.8%, with acute cases constituting 48.9% and chronic cases 29.9%. Female participants were identified as having a protective effect against gastritis (Adjusted Odds Ratio [AOR]=0.05, p=0.023), whereas the routine use of non-steroidal anti-inflammatory drugs (NSAIDs) significantly raised the risk (Crude Odds Ratio [COR]=5.03, p=0.041). Interestingly, the presence of Helicobacter pylori was associated with a reduced risk of developing gastritis (COR=0.11, p=0.032). Other lifestyle and dietary factors did not show significant correlations.  Conclusions: The results underscore the protective influence of gender and the associated risks of NSAID intake regarding gastritis among Somali adults. The unexpected finding of H. pylori infection linked to lower gastritis risk deserves further exploration. There is an urgent need for targeted public health strategies to address the effects of gastritis in Somalia.

show abstract

Prevalence and Risk Factors of Gastritis in Shahdara and Associated Areas

Cited by 2 publications

References 8 publications

A prospective observational study of estimating drug related problems and clinical outcomes in subtypes of stroke patients

A prospective observational study of estimating drug related problems and clinical outcomes in subtypes of stroke patients

Risk Factors Associated with Gastritis among Adult Patients Attending at Capital Hospital in Mogadishu- Somalia

Contact Info

Product

Resources

About