Prevalence and risk factors of Hepatitis C among individuals presenting to HIV testing centers, Hawassa city, Southern Ethiopia

Alemayehu, Addisu; Tassachew, Yayehyirad; Sisay, Zufan; Shimelis, Techalew

doi:10.1186/1756-0500-4-193

Cited by 18 publications

(25 citation statements)

References 18 publications

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“…This study is in agreement with previous studies conducted in Gondar among antenatal clinic attendees (7.3%) [29] , in Amhara and Tigray regions of Ethiopia -among blood donors (6.2%) [27] , in Kenya (6%) [32] and India (6.3%) among HIV infected patients [33] . However, the prevalence of HBsAg was found lower compared to the 10.9% in Gondar City among street dwellers [31] .…”

Section: Discussionsupporting

confidence: 82%

“…On the other hand, previous studies conducted in Addis Ababa and Hawassa city had reported no significant association between HCV and blood transfusion history among HIV infected patients [26,27] . The difference might be due to patients infected with HIV have lower hemoglobin value probably requiring frequent blood transfusion without following good screening methods of blood donors such as ELISA technique and HCV RNA in the study area.…”

Section: Discussionmentioning

confidence: 72%

“…For example, the 10.5% and 4.5% anti HCV prevalence reported in Hawassa city [27] and Addis Ababa [26] among HIV infected patients, respectively. This might be due to the difference in diagnostic methods in which these studies were carried out by ELISA method but in this study by serological antibody.…”

Section: Discussionmentioning

confidence: 99%

“…Prevalence of hepatitis B and hepatitis C virus infections has been studied in different parts of Ethiopia [6,7,[25][26][27][28][29][30][31] . The distribution of the viruses and risk factors for their transmission have not been well addressed in varying community groups like HIV infected patients.…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Assessment of hepatitis B virus and hepatitis C virus infections and associated risk factors in HIV infected patients at Debretabor hospital, South Gondar, Northwest Ethiopia

Balew¹,

Moges

Yismaw

et al. 2014

Asian Pacific Journal of Tropical Disease

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Section: Discussionsupporting

confidence: 82%

Section: Discussionmentioning

confidence: 72%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Assessment of hepatitis B virus and hepatitis C virus infections and associated risk factors in HIV infected patients at Debretabor hospital, South Gondar, Northwest Ethiopia

Balew¹,

Moges

Yismaw

et al. 2014

Asian Pacific Journal of Tropical Disease

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“…Ababa1658(4.8)[55]2006A. Ababa73450 (6.8)[66]2008Hawassa40042(10.5)[11]2011A. Ababa50018 (3.6)[53]2011Mekele17416(9.2)[12]2012D/ Tabour3955(1.3)[67]2013A.Ababa38725(6.5)[68]2013Gondar40022(5.5)[64]2013Bahirdar26959(21.9) a [100]2014Bahirdar25314(5.5)[69]Others b 2006Gondar4806 (1.3)[39]2006A.…”

Section: Resultsmentioning

confidence: 99%

Hepatitis viruses in Ethiopia: a systematic review and meta-analysis

et al. 2016

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BackgroundThe existing seroepidemiological data on viral hepatitis in Ethiopia showed a wide variation in prevalence pattern and the clinical and public health burden have been underestimated. The aim of this systematic review and meta-analysis was to provide a clear and comprehensive estimation of viral hepatitis epidemiology and the potential clinical burdens in Ethiopia.MethodsA comprehensive literature search was carried out from five decades (1968–2015) published studies from biomedical databases; PubMed, Google scholar, Medline and Web of Science.ResultsThe overall pooled prevalence of hepatitis B virus (HBV) was 7.4% (95%CI: 6.5–8.4). The pooled prevalence among subgroups showed 5.2% (95%CI: 3.7–7.4) in human immunodeficiency virus (HIV) infected individuals, 8.0% (95%CI: 5.9–10.7) in community based studies, 8.4% (95%CI: 5.4–12.7) in blood donors, 11.0% (95%CI: 7.5–15.9) in immigrants and 6.9% (95%CI: 5.6–8.5) in other groups. Among study parameters considered during meta-regression analysis, only study years were associated with a decreasing HBV prevalence rate over time. The overall pooled prevalence of anti-hepatitis C virus antibody (anti-HCV) was 3.1% (95%CI: 2.2–4.4). Unlike HBV, the anti-HCV prevalence in HIV infected individuals was higher (5.5%, 95%CI: 3.8–7.8%, p = 0.01) than the prevalence observed in the other subgroup of study population. Although relatively few data were available, hepatitis virus A (HAV), D (HDV) and E (HEV) were also circulated in Ethiopia.ConclusionsThis review indicates that all types of viral hepatitis origins are endemic in Ethiopia. Adapting a recommended diagnostic and treatment algorithm of viral hepatitis in the routine healthcare systems and implementing prevention and control policies in the general population needs an urgent attention.Electronic supplementary materialThe online version of this article (doi:10.1186/s12879-016-2090-1) contains supplementary material, which is available to authorized users.

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Current status of hepatitis C virus among people living with human immunodeficiency virus in Egypt

Elsharkawy

Alem

Cordie

et al. 2021

Transactions of the Royal Society of Tropical Medicine and Hygiene

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Background Human immunodeficiency virus (HIV)–hepatitis C virus (HCV) co-infection is increasing due to their similar routes of transmission. Co-infection poses a big challenge. Information on the prevalence of HCV infection in Egyptian HIV individuals is scarce. Methods A cross-sectional study was conducted on 1004 HIV individuals who were recruited from July 2018 to March 2019. Blood samples obtained from HIV individuals were subsequently screened for HCV antibodies using the Murex anti-HCV (version 4) enzyme-linked immunosorbent assay test. HCV RNA was performed only on anti-HCV antibody–positive samples. Logistic regression was used to identify factors associated with HCV seroprevalence using SPSS (IBM, Armonk, NY, USA). Results Among 1004 participants, 349 exhibited a positive result for anti-HCV antibodies (34.8% [95% confidence interval 31.81 to 37.8]). The most commonly self-reported risk factor of HIV infection by the co-infected participants was intravenous drug use (IDU) (303/349 [86.8%]). In multinomial analysis, risk factors identified as statistically associated with HCV seroprevalence include IDU, history of surgical operations and dental procedures and HIV viral load (p<0.001, 0.032, <0.001 and 0.006, respectively). Under combination antiretroviral therapy (cART), the proportion of HIV mono-infected individuals with an undetectable HIV viral load was significantly higher than those with co-infection (p<0.0007). We also found that HIV–HCV co-infected participants exhibited significantly higher CD4+ cell counts than those with HIV mono-infection (p=0.04). Conclusions The prevalence of HIV–HCV co-infection is higher in Egypt compared with other countries in Africa. It is essential to screen all HIV-infected patients for HCV infection for early identification, counselling and initiation of anti-HCV treatment.

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Prevalence and risk factors of Hepatitis C among individuals presenting to HIV testing centers, Hawassa city, Southern Ethiopia

Cited by 18 publications

References 18 publications

Assessment of hepatitis B virus and hepatitis C virus infections and associated risk factors in HIV infected patients at Debretabor hospital, South Gondar, Northwest Ethiopia

Assessment of hepatitis B virus and hepatitis C virus infections and associated risk factors in HIV infected patients at Debretabor hospital, South Gondar, Northwest Ethiopia

Hepatitis viruses in Ethiopia: a systematic review and meta-analysis

Current status of hepatitis C virus among people living with human immunodeficiency virus in Egypt

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