Prevalence and Risk Factors of HCV Infection among Haemodialysis Patients at Dialysis Centers in Khartoum State - Sudan

Abdalla, Eltagi A. M.; Shaaban, Kamil; Elkhidir, Isam M

doi:10.9790/0853-1603088388

Cited by 3 publications

(2 citation statements)

References 19 publications

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“…On the other hand, the prevalence of HBV among HD patients was estimated to be (0–6.6%) in developed countries [ 24 ]. Our results are similar to previous studies from other developing Arab countries where the prevalence rates of HBV and HCV were showed to be 3% and 21.7% respectively in Yemen [ 12 ] and about 20.9% of the overall HD patients were infected with HCV in Sudan [ 25 ]. However, the prevalence rates of HBV/HCV in our study were higher than those reported from neighboring countries such as Lebanon (1.6%:4.7%) [ 26 ], Iraq ( 3.2%/3.4%) [ 7 ], and Palestine (3.8%/7.4%) [ 5 ].…”

Section: Discussionsupporting

confidence: 92%

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Seroprevalence and risk factors of HBV, HCV and HIV among hemodialysis patients: a multicenter cross-sectional study from Damascus Syria

Altinawe,

Akkawi,

Kharrat Helu

et al. 2024

BMC Infect Dis

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Objective The aim of this study is to determine the prevalence rates of hepatitis B virus (HBV), hepatitis C virus (HCV), and human immunodeficiency virus (HIV) infections among hemodialysis (HD) patients as well as to identify associated risk factors. Methodology A multicenter cross-sectional study involved patients who had been on HD for at least three months. The study was conducted at five HD centers in Damascus, Syria from August 2019 to September 2021. HBsAg, HCV-Ab and HIV (antibody/antigen) seropositivity were identified using the third generation ELISA technique. Patients’ information was extracted from their records and by face-to-face interview. Multiple logistic regression models were applied to identify risk factors associated with HBV or HCV seropositivity. The significance level was set at 5%. Results A total of 637 patients were included in the study with a mean age (SD) of 50.5 (15.6) years and 56.7% of them were men. The dialytic age ranged from one to thirty years with a mean (SD) of 6.10 (5.6) years. The prevalence of positive hepatitis B surface antigen, anti-HCV, co-infection of HBV and HCV, and anti-HIV (antibody/antigen) were 3.2%, 22.1%, 0.7%, and 0%, respectively. After controlling for co-variables, hepatitis B vaccine was the only predictor of seropositivity of HBV (OR: 0.15, 95% CI: 0.057–0.393, P < 0.001), as it significantly protected against contracting HBV. On the other hand, the dialytic age (OR: 1.42, 95% CI: 1.12–1.94, P = 0.032) and the dialysis center were significant factors affecting the prevalence of HCV. Conclusions The prevalence of HCV and HBV infections among HD patients in Damascus, Syria has decreased remarkably compared with the results from 2001. Nevertheless, it is still considered relatively high. Thus, there is an urgent need to strengthen the prevention and control measures for viral infection transmission in HD centers in Damascus.

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Section: Discussionsupporting

confidence: 92%

“…Other risk factors reported by other studies such as history of blood transfusion [ 15 , 34 ], history of surgery [ 25 , 36 ], and male sex [ 12 ] were not significantly associated with HCV prevalence among our study patients. However, the risk factors for HCV infection among HD patients varies notably between countries.…”

Section: Discussioncontrasting

confidence: 43%

Seroprevalence and risk factors of HBV, HCV and HIV among hemodialysis patients: a multicenter cross-sectional study from Damascus Syria

Altinawe,

Akkawi,

Kharrat Helu

et al. 2024

BMC Infect Dis

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Detecting and genotyping of HCV among hemodialysis patients in Diyala governorate

Khalaf¹,

Hussein²

2022

AIP Conference Proceedings

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Malnutrition inflammation index in chronic haemodialysis patients with or without hepatitis C virus infection

Ramadan

Ahmed

Aref

et al. 2020

Egypt Liver Journal

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Background Hepatitis C virus infection is one of the main causes of chronic liver disease worldwide. Both chronic hepatitis C and chronic kidney disease are common and serious diseases; this work aimed to determine the clinical impact of HCV infection on malnutrition inflammation index score in chronic kidney disease patients. This study was conducted on 96 patients on haemodialysis. They were divided into two groups. The first group was composed of 46 patients who were on maintenance haemodialysis and had chronic hepatitis C. The second group was composed of 50 patients on haemodialysis who were negative for hepatitis C. Results HCV-infected patients were associated with higher malnutrition inflammation score values (10% had MIS 16–20) compared to non-infected patients (2% only had MIS 16–20). Conclusion The prevalence of malnutrition was higher in the HCV-positive than the HCV-negative group.

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Prevalence and Risk Factors of HCV Infection among Haemodialysis Patients at Dialysis Centers in Khartoum State - Sudan

Cited by 3 publications

References 19 publications

Seroprevalence and risk factors of HBV, HCV and HIV among hemodialysis patients: a multicenter cross-sectional study from Damascus Syria

Seroprevalence and risk factors of HBV, HCV and HIV among hemodialysis patients: a multicenter cross-sectional study from Damascus Syria

Detecting and genotyping of HCV among hemodialysis patients in Diyala governorate

Malnutrition inflammation index in chronic haemodialysis patients with or without hepatitis C virus infection

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