Prevalence and risk factors of asymptomatic colorectal diverticulosis in Taiwan

Wang, Fuwei; Chuang, Hung‐Yi; Tu, Ming-Shium; King, Tai-Ming; Wang, Jui-Ho; Hsu, Chao‐Wen; Hsu, Ping‐I; Chen, Wen‐Chi

doi:10.1186/s12876-015-0267-5

Cited by 56 publications

(78 citation statements)

References 25 publications

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“…In our cohort, the detection rate of CRD increased annually and presented an upward trend with population aging. CRD was more frequently seen in the people aged ≥60 years (3.16%), especially in the 75-89 age group (4.96%), which might explain why a relatively high detection rate of 13.5% in asymptomatic Taiwanese who were undergoing health check-up from 2009 to 2011 [7]. Our finding is basically consistent with previous research results of Europe and the United States [8,9].…”

Section: Discussionsupporting

confidence: 90%

Gender, Age, and Concomitant Diseases of Colorectal Diverticulum in China: A Study of 7,964 Cases

Wang

Dai

et al. 2018

Dig Dis

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Aim: To analyze the epidemiological features of colorectal diverticulum (CRD) in China. Methods: We retrospectively analyzed CRD patients in 8 tertiary hospitals located in 5 regions of China from 2000 to 2016. The detection rates, number and distribution, demographic information, concomitant disorders, and their associations were investigated. Results: Of 3,446,118 cases, 7,964 (2.3%) were CRD with a mean age of 56 years (11–92 years). The detection rate increased yearly and with increasing age. Males had a higher detection rate than females (3.0 vs. 1.47%, p < 0.01) and 1.8-times higher increase rate. The detection rate increased with age; however, females of > 60 years had a 2.8-times increasing rate than males. CRD occurred most frequently in the right-side colon, followed by rectum. Multiple diverticula were common in males and increased with age, with a 3-times higher increase rate than single lesion. Single-segment CRD occurred more frequently in males than in females (80.1 vs. 76.4%, p < 0.01). Concurred colon polyps were seen in 51.05% cases. Conclusion: CRD detection rates increased annually and with age, particularly in senior females in China. Multiple diverticula were common in males and increased with age. CRD was predominant in the right-side colon. Polyps are the most common comorbidity associated with CRD.

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Section: Discussionsupporting

confidence: 90%

Gender, Age, and Concomitant Diseases of Colorectal Diverticulum in China: A Study of 7,964 Cases

Wang

Dai

et al. 2018

Dig Dis

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“…The prevalence of diverticulosis was 12% in Korea (mean age 51) 9 and 14% in Taiwan (mean age 53). 10 The prevalence of diverticulosis was 25% in Japan (mean age 58). 11 Proximal diverticula were more common in these populations although the distal colon was not spared.…”

Section: Discussionmentioning

confidence: 99%

Distribution and Characteristics of Colonic Diverticula in a United States Screening Population

Peery

Keku

Martin

et al. 2016

Clinical Gastroenterology and Hepatology

146

113

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Background & Aims Colonic diverticula are the most common finding from colonoscopy examinations. Little is known about the distribution of colonic diverticula, which are responsible for symptomatic and costly diverticular disease. We aimed to assess the number, location, and characteristics of colonic diverticula in a large US screening population. Methods We analyzed data from a prospective study of 624 patients (mean age, 54 years) undergoing screening colonoscopy at the University of North Carolina Hospital from 2013 through 2015. The examination included a detailed assessment of colonic diverticula. To assess the association between participant characteristics and diverticula, we used logistic regression to estimate odds ratios (ORs) and 95% confidence intervals (CIs). Results Of our population, 260 patients (42%) had one or more diverticula (mean number 14; range, 1–158). Participants with diverticula were more likely to be older, male, and have a higher body mass index than those without diverticula. The distribution of diverticula differed significantly by race. Among Whites, 75% of diverticula were in the sigmoid colon, 11% in the descending splenic flexure, 6% in the transverse colon, and 8% were in the ascending colon or hepatic flexure; in Blacks 64% of diverticula were in the sigmoid colon, 8% in the descending colon or splenic flexure, 7% in the transverse colon, and 20% in the ascending colon or hepatic flexure (P=.0008). The proportion of patients with diverticula increased with age: 35% were 50 years or younger, 40% were 51–60 years, and 58% were older than 60 years. The proportion of patients with more than 10 diverticula increased with age: 8% were 50 years or younger, 15% were 51–60 years, and 30% were older than 60 years. Conclusions Older individuals not only have a higher prevalence of diverticula than younger individuals, but also a greater density, indicating that this is a progressive disease. Blacks have a greater percentage of their diverticula in the proximal colon and fewer in the distal colon compared with Whites. Understanding the distribution and determinants of diverticula is the first step in preventing diverticulosis and its complications.

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“…Additionally, the prevalence of diverticulosis was 12% in Korea (mean age: 51 years) [13] and 14% in Taiwan (mean age: 53 years) [14]. Barium studies in Japan have shown a significant increase in the prevalence of diverticulosis in the late 1900s, from 2.1% in 1967 and 7.8% in 1983 to 28% in 1997; the increase may be associated with the adoption of a Western lifestyle [15][16][17][18].…”

Section: Diverticulosismentioning

confidence: 99%

“…The incidence of left-sided diverticular disease has markedly increased with age but has not significantly changed over time. In Korea, 15% of patients with colonic diverticulosis had distal diverticula [13], whereas half of the Japanese and Taiwanese populations with colonic diverticulosis had distal diverticula [14,15].…”

Section: Diverticulosismentioning

confidence: 99%

The Burden of Diverticular Disease and Its Complications: West versus East

Imaeda¹,

Hibi²

2018

Inflamm Intest Dis

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Background: Colonic diverticulosis is prevalent and increasing not only in Western but also in Asian countries. Diverticulosis can be complicated by diverticulitis and diverticular bleeding. Diverticular disease is a burdensome digestive disease, because it is a major cause of hospital admissions and is associated with significant health-care costs. Summary: The incidence of diverticulosis increases with age. Most cases of diverticulosis in Western countries involve the left side of the colon, while diverticulosis is predominantly present on the right side of the colon in Asian countries. The incidence of diverticulitis also increases with age. Diverticulitis is predominantly located on the left side of the colon in Western countries, while it is predominantly located on the right side of the colon in Asian countries. The overall complication rate is higher in left-sided than in right-sided diverticulitis. The incidence of diverticular bleeding also increases with age. The right colon is the source of diverticular bleeding in more than 50% of patients in Western countries. In Asian countries, age greater than 70 years and both-sided diverticulosis increase the bleeding risk. Key Messages: In Western countries, diverticulosis and diverticulitis are predominantly located on the left side of the colon, whereas they are predominantly present on the right side of the colon in Asian countries. Diverticular bleeding is predominantly located on the right side in Western countries, and both-sided diverticulosis increases the risk of bleeding in Asian countries. Diverticular disease with complications requires admission and operation; moreover, it recurs frequently. Therefore, diverticular disease is associated with a significant economic burden in terms of health-care costs and resource utilization.

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Prevalence and risk factors of asymptomatic colorectal diverticulosis in Taiwan

Cited by 56 publications

References 25 publications

Gender, Age, and Concomitant Diseases of Colorectal Diverticulum in China: A Study of 7,964 Cases

Gender, Age, and Concomitant Diseases of Colorectal Diverticulum in China: A Study of 7,964 Cases

Distribution and Characteristics of Colonic Diverticula in a United States Screening Population

The Burden of Diverticular Disease and Its Complications: West versus East

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