Prevalence and sources of occupational contact sensitization to acrylates in Italy

Abstract

Acrylate-based products are widely utilized in the industrialized world and in the domestic environment. The aim of this study was to evaluate the prevalence and sources of occupational contact sensitization to acrylates in a selected population. Between January 1987 and April 1992, 82 patients suspected of occupational acrylic sensitization were patch tested with the GIRDCA standard series and an extensive acrylate series. Over this 5-year period, we detected sensitization to acrylates in 13.4% of cases. Dental materials and anaerobic sealants were the most important sources of acrylate sensitization. Among acrylic monomers, ethylene glycol dimethacrylate was the most frequent contact sensitizer in our study. Acrylate additives were also important sources of contact dermatitis in our patients. Although the clinical picture of airborne contact dermatitis due to acrylates has rarely been reported in the literature, it was commonly observed in our patients.

Allergic Contact Dermatitis in Dentists and Dental Nurses

“…The most popular composites include Kerr-Herculit (Kerr Manufacturing Co., USA), Helimolar and Isomolar (Vivadent, Liechtenstein), Degufill (Degussa, Germany) and Ultra-Blend (Ultradent Products, USA). It is estimated that the chemical compounds included in lastgeneration acrylates are characterized by stronger sensitizing properties than methyl methacrylate used for quite some time already in dental prosthetics [13][14][15]. Our results confirm those observations.…”

Atypical pattern of (meth)acrylate allergic contact dermatitis in dental professionals

“…6 (Meth)acrylate ACD in dental professionals mainly manifests as hand eczema, though there are also case reports of airborne ACD affecting the face. 2,7 The commonest site of ACD in dental personnel has been reported to be the finger tips. In one study 93% of contact dermatitis was distributed on the finger tips: however, involvement of the lateral aspect of fingers was almost as common.…”

“…1 The distribution of (meth)acrylate ACD has been reported to typically affect the finger tips/pulps as a result of dextrous handling of relevant materials. 2,3 We report two cases of (meth) acrylate ACD in dental professionals, where the pattern of the dermatitis was not typical. Further history concerning individual working habits provided a clear explanation for this distribution.…”

Sensitization and Development of Allergic Contact Dermatitis Caused by a Single Contact with an Electrosurgical Grounding Plate Containing Acrylates

“…its single components hydroxyethyl acrylate and hydroxyethyl methacrylate. Usually dental materials and anaerobic sealants are the most important sources of acrylate sensitization, which can also be caused by printing inks, acrylic bone cement and limb prostheses, soft lenses, hearing aids and laboratory media [5]as well as sculptured nails [6]and nail lacquer [7]. As the patient had never had contct with such acrylate-containing materials in the past and developed the contact dermatitis 14 days after application of the grounding plate in contrast to allergic reactions within 48 h during patch testing, there is a high probability of primary sensitization by contact with the grounding plate during surgery.…”