Prevalence and spectrum of coronary artery anomalies in 8021 patients: A single center study in South India

Abstract

ObjectiveTo identify the prevalence of coronary artery anomalies (CAAs) and their subtypes based on Angelini et al. classification in symptomatic yet stable population of South India using 64- slice dual source multi detector CT coronary angiography (MDCT-CA).MethodsWe retrospectively reviewed reports of 8021 symptomatic patients predominantly South Indians who were referred for CT coronary angiography (CT-CA) to our tertiary cardiac care center in Hyderabad, India from January 2011 to March 2017.ResultsWe identified a total of 838 coronary artery anomalies in 812 patients with a prevalence of 10.09%. 96.9% of patients were older than 30 years of age with a M:F ratio of 1.39:1. Coronary artery disease (CAD) was seen in 61.5% of these patients. Among these anomalies, myocardial bridging (MB) was the most common anomaly followed by anomalous location of coronary ostium at improper sinus (ACOIS).ConclusionThere is no significant difference in prevalence of CAAs (including and excluding MB) in Indian and World population. CAAs were more common in males than females and most of these patients remain asymptomatic during first three decades of their life. Myocardial bridging is the most common anomaly detected by MDCT-CA followed by ACOIS. Right coronary artery (RCA) arising from left coronary sinus (LCS) is the most commonly encountered ACOIS.

Incidence, Characteristics and Atherosclerotic Involvement of Coronary Artery Anomalies in Adult Population Undergoing Catheter Coronary Angiography

“…Many large angiographic studies related to CAAs have not reported on incidence of dual LAD. Two large studies which reported dual LAD are by Nawale et al and Sirasapalli et al [29, 40]. Nawale et al found only a single case of dual LAD with an incidence of 0.02%.…”

Prevalence and Spectrum of Coronary Anomalies Detected on Coronary Computed Tomography Angiography: A single centre experience in Oman

“…In the literature, discrepancies in the prevalence of CAAs are largely due to the inclusion or exclusion of MB due to the fact that some authors consider MB as a normal variant, whereas others consider it an anomaly 12,14,15. When MB is excluded, the prevalence of CAAs ranges between 0.5–3.1%; however, when MB is included, prevalence increases to 7.9–18.4% 3. In the current study, the prevalence of CAAs, excluding MB, was 1.3% which falls within the reported range in the literature 3,5,11,16.…”

“…When MB is excluded, the prevalence of CAAs ranges between 0.5–3.1%; however, when MB is included, prevalence increases to 7.9–18.4% 3. In the current study, the prevalence of CAAs, excluding MB, was 1.3% which falls within the reported range in the literature 3,5,11,16. To the best of the authors’ knowledge, this study is the first to estimate the prevalence and spectrum of CAAs in the general Omani population.…”

Anomalous aortic origin of a coronary artery in two children

“…As in case 1, the left coronary artery originating from the noncoronary sinus is extremely rare. [2][3][4] The problem with the patient in case 1 was that he was diagnosed with vasospastic angina and lost consciousness again after discharge. Diagnosis of AAOCA via cardiac catheterization alone is challenging.…”

“…Congenital coronary artery anomaly is a rare condition, and it has several variations. Sirasapalli and colleagues 2 claimed that among the anomalies of the coronary artery, 0.35% of AAOCA cases originate from the noncoronary sinus. As in case 1, the left coronary artery originating from the noncoronary sinus is extremely rare.…”