2015
DOI: 10.4172/2155-9864.1000280
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Prevalence and Trends of Common Transfusion Transmitted Infections Using Serological and Nucleic Acid Markers in Saudi Blood Donors

Abstract: Background: Epidemiologic studies on the prevalence of transfusion-transmitted infections (TTIs) in Saudi Arabia (SA) regions are limited. This study investigated the prevalence of HBV, HCV, and HIV using both serological and nucleic acid testing (NAT) methods to determine temporal and geographic trends among blood donors in Makkah. Our secondary objective was to realize the most suitable NAT format, without compromising sensitivity of NAT results by using individualized or mini-pool testing.

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Cited by 5 publications
(4 citation statements)
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“…This study trend estimated conforms to the trend of HIV cases in blood donors as stipulated by earlier studies [15,16].…”
Section: Discussionsupporting
confidence: 88%
See 1 more Smart Citation
“…This study trend estimated conforms to the trend of HIV cases in blood donors as stipulated by earlier studies [15,16].…”
Section: Discussionsupporting
confidence: 88%
“…Hepatitis B virus is highly contagious and relatively easy to be transmitted from one infected individual to another by blood transfusion, during birth, by unprotected sex, and by sharing needles and has a relatively higher prevalence in the tropics. [11,15].…”
Section: Introductionmentioning
confidence: 99%
“…By assessing these rates during this period, we were able to identify the trend for these infections, which found to be an increasing trend, after adjusting to age and the total population. Despite this increasing trend, yet, the rates were less than what was found in countries from different regions, such as Saudi Arabia, Egypt, India and Nigeria [27][28][29][30].…”
Section: Discussionmentioning
confidence: 98%
“…Saudi Arabia, where the positivity rates ranged between 6.8 and 7.4 from 2011through 2014. (26) Moreover, the trends for each infection of the TTs were also assessed in this study. The results showed a declining trend for HBsAg throughout the years, form 0.34 in 2013 to 0.29 in 2017.…”
Section: Discussionmentioning
confidence: 99%