Prevalence, burden of disease, and lost in health state utilities attributable to chronic musculoskeletal disorders and pain in Chile

Abstract

Background Musculoskeletal disorders are a leading cause of disability adjusted life years (DALY) in the world. We aim to describe the prevalence and to compare the DALYs and loss of health state utilities (LHSU) attributable to common musculoskeletal disorders in Chile. Methods We used data from the Chilean National Health Survey carried out in 2016–2017. Six musculoskeletal disorders were detected through the COPCOPRD questionnaire: chronic musculoskeletal pain, chronic low back pain, chronic shoulder pain, osteoarthritis of hip and knee, and fibromyalgia. We calculated the DALY for each disorder for 18 sex and age strata, and LHSU following an individual and population level approaches. We also calculated the fraction of LHSU attributable to pain. Results Chronic musculoskeletal pain disorder affects a fifth of the adult population, with a significant difference between sexes. Among specific musculoskeletal disorders highlights chronic low back pain with the highest prevalence. Musculoskeletal disorders are a significant cause of LHSU at the individual level, especially in the case of fibromyalgia. Chronic musculoskeletal pain caused 503,919 [283,940 - 815,132] DALYs in 2017, and roughly two hundred thousand LSHU at population level, which represents 9.7% [8.8–10.6] of the total LSHU occurred in that year. Discrepancy in the burden of musculoskeletal disorders was observed according to DALY or LSHU estimation. The pain and discomfort domain of LHSU accounted for around half of total LHSU in people with musculoskeletal disorders. Conclusion Chronic musculoskeletal pain is a major source of burden and LHSU. Fibromyalgia should deserve more attention in future studies. Using the attributable fraction offers a straightforward and flexible way to explore the burden of musculoskeletal disorders.

Cost analysis of chronic pain due to musculoskeletal disorders in Chile

“…We modeled a hypothetical estimated cohort through the prevalence of each MSKD disorder, previously defined and estimated according to Zitko et al [ 18 , 19 ]. The data was obtained from the National Health Survey 2016–2017 (ENS 2016–7) [ 20 ].…”

“…It represents the proportion of the disutility caused by chronic pain and the number of n individuals alive (n) at cycle t [ ]. Disutility was obtained from the Zitko P. et al [ 19 ] study. Depression/anxiety prevalence was estimated using the depression/anxiety caused by a chronic pain-attributable fraction (dPAF) [ 16 ] and then multiplying by the number of prevalent cases for each health problem.…”

Consideraciones para el uso de tramadol en dolor crónico no oncológico en APS

“…A su vez, el DC secundario se clasifica en dolor crónico oncológico y dolor crónico no oncológico (DCNO), el que puede ser musculoesquelético (DCME), neuropático (DCN), post traumático, cefálico-orofacial o visceral (Treede et al, 2019). En Chile, la prevalencia del DCNO es 34,7%, siendo más frecuentes el DCME (20%), el DCN (12%) y la fibromialgia (3,9%) (Zitko et al, 2021;Durán et al, 2023).…”

Effects of Protein Supplementation Combined with Resistance Exercise Training on Walking Speed Recovery in Older Adults with Knee Osteoarthritis and Sarcopenia

“…Knee osteoarthritis (KOA), the most prevalent musculoskeletal disorder among older adults [ 1 ], is recognized as a major cause of chronic pain and disability [ 2 , 3 , 4 , 5 ]. KOA imposes a substantial burden on the physical health of affected individuals, resulting in significant economic costs to healthcare systems across regions and countries [ 6 , 7 , 8 , 9 , 10 ]. KOA is primarily characterized by pain and muscle weakness, which greatly affect the physical mobility, especially walking speed (WS), of the lower extremities [ 5 , 11 , 12 ].…”