Prevalence, characteristics, and prognosis role of type 1 ST elevation in the peripheral ECG leads in patients with Brugada syndrome

Rollin, Anne; Sacher, Frédéric; Gourraud, Jean‐Baptiste; Pasquié, Jean Luc; Raczka, Frank; Duparc, Alexandre; Mondoly, Pierre; Cardin, Christelle; Delay, Marc; Chatel, Stéphanie; Derval, Nicolas; Denis, Arnaud; Sadron, Marie; Davy, Jean‐Marc; Hocini, Mélèze; Jaı̈s, Pierre; Jesel, Laurence; Haı̈ssaguerre, Michel; Probst, Vincent; Maury, Philippe

doi:10.1016/j.hrthm.2013.03.001

Cited by 59 publications

(31 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Apart from a few exceptions, the studied population has been already described in our previously reports [16,17]. Hundred seventeen patient were included in the FINGER (France, Italy, Netherlands, Germany) Brugada syndrome registry [2], 36 of them and 30 additional patients being also included in a previous study [18].…”

Section: Resultsmentioning

confidence: 99%

Increased Tpeak-Tend interval is highly and independently related to arrhythmic events in Brugada syndrome

et al. 2015

View full text Add to dashboard Cite

show abstract

Section: Resultsmentioning

confidence: 99%

Increased Tpeak-Tend interval is highly and independently related to arrhythmic events in Brugada syndrome

et al. 2015

View full text Add to dashboard Cite

show abstract

“…The presence of a type I Brugada pattern in infero-lateral leads was found in $10% of Brugada patients and has been associated with increased risk of cardiac events [59,60]. Similarly, the presence of J waves in infero-lateral leads was found in 11-15% of BrS patients [5,61] and has also been described as a risk marker for cardiac events and arrhythmic storms in several studies [62][63][64].…”

Section: Other Risk Markersmentioning

confidence: 94%

Brugada syndrome

Adler

2016

Current Opinion in Cardiology

View full text Add to dashboard Cite

show abstract

“…: 44 prolonged QRS duration 31, 45–47 and early repolarization pattern in the inferolateral leads. 30, 31, 47, 48 …”

Section: Risk Stratification In Brsmentioning

confidence: 99%

“…Commonly accepted risk factors include Spontaneous Type 1 BrS ECG, history of cardiac events or syncope likely due to VT/VF, 8, 33–35 aborted sudden cardiac death, documented VT/VF, nocturnal agonal respiration, late potentials on epicardial bipolar electrogram or SAECG, 36–42 T wave amplitude variability, 37 short ventricular refractory period (< 200 ms), 34 fragmented QRS, 34, 43 and ST segment elevation in the peripheral leads, particularly aVR. 44 …”

Section: Risk Stratification In Brsmentioning

confidence: 99%

Novel therapeutic strategies for the management of ventricular arrhythmias associated with the Brugada syndrome

Patocskai

Antzelevitch

2015

Expert Opinion on Orphan Drugs

View full text Add to dashboard Cite

Introduction Brugada syndrome (BrS) is an inherited cardiac arrhythmia syndrome characterized by prominent J waves appearing as distinct coved type ST segment elevation in the right precordial leads of the ECG. It is associated with a high risk for sudden cardiac death. Areas Covered We discuss 1) ECG manifestations of BrS which can be unmasked or aggravated by sodium channel blockers, febrile states, vagotonic agents, as well as tricyclic and tetracyclic antidepressants; 2) Genetic basis of BrS; 3) Ionic and cellular mechanisms underlying BrS; 4) Therapy involving devices including an implantable cardioverter defibrillator (ICD); 5) Therapy involving radiofrequency ablation; and 6) Therapy involving pharmacological therapy which is aimed at producing an inward shift in the balance of the currents active during phase 1 of the right ventricular action potential either by boosting calcium channel current (isoproterenol, cilostazol and milrinone) or by inhibition of transient outward current Ito (quinidine, bepridil and the Chinese herb extract Wenxin Keli). Expert Opinion This review provides an overview of the clinical and molecular aspects of BrS with a focus on approaches to therapy. Available data suggest that agents capable of inhibiting the transient outward current Ito can exert an ameliorative effect regardless of the underlying cause.

show abstract

Prevalence, characteristics, and prognosis role of type 1 ST elevation in the peripheral ECG leads in patients with Brugada syndrome

Cited by 59 publications

References 28 publications

Increased Tpeak-Tend interval is highly and independently related to arrhythmic events in Brugada syndrome

Increased Tpeak-Tend interval is highly and independently related to arrhythmic events in Brugada syndrome

Brugada syndrome

Novel therapeutic strategies for the management of ventricular arrhythmias associated with the Brugada syndrome

Contact Info

Product

Resources

About