Prevalence, characteristics and risk factors in a Moroccan cohort of Long-Covid-19

Otmani, Hicham El; Nabili, Salma; Berrada, M.; Bellakhdar, Salma; Moutawakil, Bouchra El; Rafai, M.A.

doi:10.1007/s10072-022-06138-0

Cited by 21 publications

(34 citation statements)

References 21 publications

(8 reference statements)

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“…By the COVID-19 pandemic in Morocco, several studies have been carried out and covered the several issues that were considered challenging the health system [ 14 , 24 , 26 – 49 , 63 ]. However, there was inadequate data assessing the COVID-19 prevalence among Moroccan healthcare workers.…”

Section: Discussionmentioning

confidence: 99%

“…Predictive variables for impaired mental health were also investigated within medical students since they underwent a major change in education and training during the pandemic [45][46][47]. In addition, symptoms related to "Long-COVID-19" as well as signs of headaches and skin allergic reactions caused by PPE were exanimated among HCWs [48][49][50]. However, there was not any published study assessing the prevalence of COVID-19 and its risk factors among physicians.…”

Section: Introductionmentioning

confidence: 99%

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Prevalence and associated factors of COVID-19 among Moroccan physicians: A cross-sectional study

Baldi

Laghrissi²,

Marso³

et al. 2022

PLoS ONE

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Background Coronavirus disease (COVID-19) has emerged and spread rapidly worldwide and established a global public health crisis in early 2020. The first Moroccan case was reported on March 2, 2020. Since then, healthcare workers (HCWs) played a major role in saving human lives threatened by COVID-19. This study aimed to assess the prevalence of COVID-19 infection among Moroccan physicians and to report associated risk factors prior vaccination campaign. Methods A cross-sectional study was carried out in the Fez-Meknes region of Morocco, 545 physicians’ data was collected using a self-reported online questionnaire. The data collection was done between December 1, 2020, and February 1, 2021. Results The prevalence of COVID-19 among physicians was 27.3%. The mean age of the confirmed COVID-19 group was 38.4±12.9 years old. There was no association between COVID-19 infection and preventive measures compliance by physicians and healthcare authorities in the workplace. However, multivariate analysis strengthened the following factors such as increased risk of COVID-19 infection within men ☯aOR:1.896; 95% IC 1.272–2.828; p = 0.002]; the presence of at least one comorbidity ☯aOR:2.268; 95%IC 1.414–3.637; p = 0.001]; and working at a university or military hospitals ☯aOR:2.578; 95%IC 1.667–3.989; p = 0.001]. Conclusion This study allows comparing COVID-19 prevalence among healthcare workers before and after vaccination programs. This should support better preparation strategy for any future pandemics with appropriate and increased awareness for men, carrying comorbidity, and working environment with high COVID-19 disease management.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Prevalence and associated factors of COVID-19 among Moroccan physicians: A cross-sectional study

Baldi

Laghrissi²,

Marso³

et al. 2022

PLoS ONE

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“…Fourteen studies were included in this review. Among them, five were case control studies conducted in South Africa and Morocco [18][19][20][21][22] , three retrospective cohort studies undertaken in Nigeria and South Africa [23][24][25] , two prospective cohort studies (South Africa and Zambia) 11,26 , two retrospective cross-sectional studies done in South Africa and Egypt 27,28 and two cross-Sectional studies undertaken Ghana and Egypt 29,30 . This review included a total of 6, 030 previously SARS-CoV-2 infected participants and 2,954 long COVID patients.…”

Section: Study and Participant Characteristicsmentioning

confidence: 99%

Burden, Causation, and Particularities of long-COVID in African populations: A rapid systematic review

Nyasulu

Tamuzi

Erasmus

2023

Preprint

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Background: The global estimated prevalence of long COVID-19 is 43%, and the most common symptoms found globally are fatigue, confusion, or lack of confusion, and dyspnea, with prevalence rates of 23%, 14%, and 13%, respectively. However, long COVID still lacks an overall review in African populations. The aim of this review was to determine the prevalence of long COVID, its most common symptoms, comorbidities, and pathophysiological mechanisms. Methods: A systematic review of long COVID in African populations was conducted. The random effects model was used to calculate the pooled prevalence rates (95% CI). If the results could not be pooled, a narrative synthesis was performed. Results: We included 14 studies from 7 African countries, totaling 6,030 previously SARS-CoV-2 infected participants and 2,954 long COVID patients. Long COVID had a pooled prevalence of 41% [26%-56%]. Fatigue, dyspnea, and confusion or lack of concentration were the most common symptoms, with prevalence rates (95% CI) of 41% [26%-56%], 25% [12%-38%], and 40% [12%-68%], respectively. Long COVID was associated with advanced age, being female, more than three long COVID symptoms in the acute phase, initial fatigue and dyspnea, post-recovery stress, sadness, and sleep disturbances, and loss of appetite at symptoms onset, mild, moderate, and severe, pre-existing obesity, hypertension, diabetes mellitus, and the presence of any chronic illness (P ≤0.05). According to our review, high micro clot and platelet poor plasma (PPP) viscosity explain the pathophysiology of long COVID. Conclusion: Long COVID prevalence in Africa was comparable to the global prevalence. However, the prevalence of the most common symptoms was higher in Africa. Comorbidities associated with long COVID may lead to additional complications in African populations due to hypercoagulation and thrombosis.

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“…6 Several studies have been conducted using different study designs and populations, with the majority finding that the risk of PCC is approximately halved in vaccinated compared to non-vaccinated individuals. [7][8][9][10][11][12][13][14][15][16][17] While most studies evaluated symptoms persisting for more than four weeks 8,9,17 or more than 12 weeks 10,12,13,15,16 after SARS-CoV-2 infection, only three assessed symptoms beyond six months and identified a lower 7 or no 11,14 risk reduction with vaccination.…”

Section: Introductionmentioning

confidence: 99%

Post COVID-19 condition after Wildtype, Delta, and Omicron variant SARS-CoV-2 infection and vaccination: pooled analysis of two population-based cohorts

Menges

Kaufmann

Amati

et al. 2022

Preprint

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Background: Post COVID-19 condition (PCC) is an important complication of SARS-CoV-2 infection, affecting millions worldwide. Further evidence is needed on the risk of PCC after vaccination and infection with newer variants. This study aimed to evaluate the prevalence and severity of PCC across different variants and vaccination histories. Methods: We used pooled data from 1350 SARS-CoV-2-infected individuals from two representative population-based cohorts in Switzerland, diagnosed between Aug 5, 2020, and Feb 25, 2022. We descriptively analysed the prevalence and severity of PCC, defined as the presence and frequency of PCC-related symptoms six months after infection, among vaccinated and non-vaccinated individuals infected with Wildtype, Delta, and Omicron SARS-CoV-2. We used multivariable logistic regression models to assess the association and estimate the risk reduction of PCC after infection with newer variants and prior vaccination. We further assessed associations with the severity of PCC using multinomial logistic regression. To identify groups of individuals with similar symptom patterns and evaluate differences in the presentation of PCC across variants, we performed exploratory hierarchical cluster analyses. Findings: We found strong evidence that vaccinated individuals infected with Omicron had a reduced risk of developing PCC compared to non-vaccinated Wildtype-infected individuals (odds ratio 0.42, 95% confidence interval 0.24-0.68). The risk among non-vaccinated individuals was similar after infection with Delta or Omicron compared to Wildtype SARS-CoV-2. We found no differences in PCC prevalence with respect to the number of received vaccine doses or timing of last vaccination. The prevalence of PCC-related symptoms among vaccinated, Omicron-infected individuals was lower across severity levels. In cluster analyses, we identified four clusters of diverse systemic, neurocognitive, cardiorespiratory, and musculoskeletal symptoms, with similar patterns across variants. Interpretation: The risk of PCC appears to be lowered with infection by the Omicron variant and after prior vaccination. This evidence is crucial to guide future public health measures and vaccination strategies. Study registrations: ISRCTN14990068, ISRCTN18181860

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Prevalence, characteristics and risk factors in a Moroccan cohort of Long-Covid-19

Cited by 21 publications

References 21 publications

Prevalence and associated factors of COVID-19 among Moroccan physicians: A cross-sectional study

Prevalence and associated factors of COVID-19 among Moroccan physicians: A cross-sectional study

Burden, Causation, and Particularities of long-COVID in African populations: A rapid systematic review

Post COVID-19 condition after Wildtype, Delta, and Omicron variant SARS-CoV-2 infection and vaccination: pooled analysis of two population-based cohorts

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