Prevalence, clinical profile and follow up of asymptomatic bacteriuria in patients with type 2 diabetes-prospective case control study in Srinagar, India

Laway, Bashir Ahmad; Nabi, Tauseef; Bhat, Moomin Hussain; Fomda, Bashir Ahmad

doi:10.1016/j.dsx.2020.12.043

Cited by 9 publications

(10 citation statements)

References 21 publications

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“…A study conducted in the KSA found that the overall prevalence of UTIs in diabetic patients was 25.3% [ 8 ]. The prevalence of diabetic UTIs was reported to be 13.8% in Ethiopia [ 29 ], 17.5% in India [ 30 ], and 9.71% in the USA [ 31 ].…”

Section: Discussionmentioning

confidence: 99%

Prevalence and Associated Risk Factors of Urinary Tract Infection among Diabetic Patients: A Cross-Sectional Study

et al. 2023

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Urinary tract infections (UTIs) are one of the most common long-term complications of diabetes mellitus (DM). Additionally, various factors, such as socio-demographics, type of DM, fasting blood glucose, regular diabetes monitoring, comorbid chronic diseases, HbA1c, body mass index (BMI), and duration of DM, are also thought to predispose individuals to developing UTIs more frequently when they have DM. This research aims to evaluate the risk factors for UTIs and their prevalence among people with DM in Saudi Arabia (KSA). This cross-sectional study was conducted among 440 adults with type 1, type 2, and gestational DM. The participants had to be at least 18 years old, of both genders, and had been suffering from DM for any period of time. A self-administered questionnaire was utilized to collect data on demographic characteristics, such as sex, age, height, weight, material state, education level, income, and clinical profiles of DM and UTI. The crude (COR) and adjusted odds ratios (AOR) were calculated using logistic regression in the IBM SPSS software. The incidence of types 1 and 2 DM and gestational diabetes reached 34.1, 60.9, and 5%, respectively. Most of the participants had first-degree relatives with DM (65.9%). UTI was common in 39.3% of participants. A chi-squared statistical analysis revealed that the frequency of UTI varied depending (χ2 = 5.176, P = 0.023) on the type of DM. Burning urination and abdominal pain were the most common symptoms. The CORs for sex, marital status, hypertension, and BMI were significant (P < 0.05) and had values of 2.68 (95% CI = 1.78–4.02), 0.57 (95% CI = 0.36–0.92), 1.97 (95% CI = 1.14–3.43), and 2.83 (95% CI = 1.19–2.99), respectively. According to the adjusted model, only sex influenced the occurrence of UTIs. The AOR for sex was 3.45 (95% CI = 2.08–5.69). Based on this study, the authorities related to the health of DM patients can use its findings to guide awareness programs and clinical preparedness.

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Section: Discussionmentioning

confidence: 99%

Prevalence and Associated Risk Factors of Urinary Tract Infection among Diabetic Patients: A Cross-Sectional Study

et al. 2023

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“…Moreover, the association between advanced age and ASB in patients with DM remains questionable [ 11 , 13 , 14 , 15 ]. There is evidence that longer duration of diabetes is correlated with ASB [ 6 , 10 , 11 , 13 ], although this association was not confirmed in other studies [ 9 , 16 , 17 ]. Furthermore, body mass index (BMI), sexual intercourse, a prior history of UTI, in addition to pyuria and diabetes complications, have also been reported as risk factors for ASB in patients with DM, even though related studies are conflicting [ 11 , 17 , 18 ].…”

Section: Introductionmentioning

confidence: 91%

“…Several risk factors, including age, sexual intercourse, as well as duration, metabolic control, and complications of diabetes have been associated with the presence of ASB in patients with DM thus far [ 8 , 9 , 10 ]. Even though there are references reporting a correlation between impairment of metabolic control and increased risk of urinary tract infection (UTI) [ 11 , 12 ], in patients with DM, the association between glycated hemoglobin (HbA1c) levels and ASB is not yet well explained [ 6 , 7 ].…”

Section: Introductionmentioning

confidence: 99%

Asymptomatic Bacteriuria in Patients with Type 2 Diabetes Mellitus

Matthiopoulou

Ιωάννου

Mathioudaki

et al. 2023

Infectious Disease Reports

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Objectives: Asymptomatic bacteriuria (ASB) is a common finding in patients with diabetes. Moreover, patients with diabetes and ASB have a greater risk for symptomatic urinary tract infections and associated severe complications. The aim of this study was to estimate the prevalence of ASB, as well as to identify independent risk factors and related pathogens associated with ASB in female and male patients with type 2 diabetes mellitus (T2D). Methods: This prospective case-control study was performed at the University hospital, and the Venezeleion General Hospital, Heraklion, Greece between 2012 and 2019. All patients with T2D attending the diabetes and hypertension outpatient clinics at both hospitals were enrolled, and data regarding their medical history and clinical and laboratory profiles were recorded. Asymptomatic patients with positive urine cultures were assigned as cases while those with negative urine cultures were designated as controls. Results: A total of 437 adult patients of which 61% were female and 39% were male patients with a mean age of 70.5 ± 9.6 years, were enrolled. The prevalence of ASB was 20.1%, in total. ASB was noted in 27% of female participants and 9.4% of male participants. Higher glycated hemoglobin (OR = 3.921, 95%CI: 1.521–10.109, p < 0.001) and urinary tract infection within the previous year (OR = 13.254, 95%CI: 2.245–78.241, p < 0.001) were independently positively associated with ASB, while higher levels of vitamin B12 were independently negatively associated with ASB (OR = 0.994 per ng/mL, 95%CI: 0.989–0.999, p < 0.001). Conclusions: Development of ASB was associated with specific factors, some of which may be modifiable. Interestingly, high B12 was found to be negatively associated with ASB.

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“…Asymptomatic bacteriuria is also more frequent in diabetic patients than in healthy controls (17% vs. 10%), and it can progress to symptomatic UTI in up to 20% of them within 6 months, especially if glycemic control is suboptimal [ 23 , 24 ].…”

Section: Risk Factors Of Ruti and Abmentioning

confidence: 99%