Introduction: High blood pressure is a public problem worldwide because of its high morbidity and mortality. The greatest burden is in low-income settings. The burden of disease has not been studied in health workers in our setting. Methods: Between December 2016 and June 2017, we carried out a cross-sectional descriptive and analytic study in two teaching hospitals in Yaounde, using the WHO STEP wise approach. Participants were consenting Physicians, Nurses, Midwives, and Nursing assistants of both sex, aged ≥ 21 years. Results: A total of 266 health workers were screened-31 Physicians, 144 Nurses, 80 Nursing assistants, and 11 Midwives. Their mean age was 41.1 ± 7.6 years (25 to 66 years), and 84.6% were females. The prevalence of Hypertension was 13.9%, of which 54.1% were newly diagnosed-Awareness rate of 45.9%. The control rate of known cases of hypertension was 64.7% (64.3% in those on monotherapy, and 66.7% in those on bitherapy). Age > 40 years, and adiposity were significantly associated with hypertension. Conclusion: Compared to the general population, the prevalence of hypertension amongst health workers was low, but with a high rate of un-awareness.