Prevalence, Demographic, and Clinical Correlates of Comorbid Depressive Symptoms in Chinese Psychiatric Patients With Alcohol Dependence

Abstract

Background: Depressive symptoms are common among psychiatric patients with alcohol dependence (AD). However, the prevalence and clinical correlates of comorbid depressive symptoms are less well studied in Chinese Han patients.Methods: In this hospital-based survey, we recruited 378 psychiatric patients diagnosed with AD according to the Diagnostic and Statistical Manual of Mental Disorders-Fourth Edition (DSM-IV). All patients completed the Beck Depression Inventory (BDI) to evaluate depressive symptoms and the Alcohol Use Disorders Identification Test (AUDIT) to assess the severity of drinking.Results: Compared to patients without depressive symptoms, 48.9% (185/378) of the patients with comorbid depressive symptoms were younger, had a more unstable marital status, had a higher AUDIT total score, and had a higher adverse consequences subscore (all P < 0.05). Further logistic regression analysis showed that unstable marital status (Odds ratios [OR] = 2.20, 95% confidence interval [CI] 1.21-3.99) and AUDIT total score (OR=1.07, 95% CI 1.03-1.11) were significantly associated with depressive symptoms. Conclusions:Our findings indicate high comorbidity between AD and depressive symptoms in Chinese psychiatric patients. Moreover, some variables are correlates of comorbid depressive symptoms. Particular attention should be paid to the early detection and intervention for this comorbid condition and its risk factors.

Correlates of Aggression in Men With Methamphetamine Use Disorder: Childhood Trauma and Methamphetamine-Use Characteristics

“…Demographic data included gender, age, education, marital status, and employment (full-time job, part-time job, or unemployment). MA-use characteristics included the age of first MA use, age of MAUD onset, duration of MA use (years from the age at first MA use to age at the time of enrollment), the longest period of MA abstinence (specifically referring to the longest voluntary MA detoxification/abstinence period rather than during compulsory treatment), MA-induced paranoia (a positive answer of the item: “Have you ever had a paranoid experience when you were using MA?”), the severity of MAUD (having six or more DSM-5 criteria for stimulant use disorder was considered severe MAUD, while two to five criteria was considered mild to moderate), co-occurring alcohol use disorder (AUD) [a score of eight or more on the Alcohol Use Disorders Identification Test (AUDIT) measured for the past year before entering the Compulsory Drug Rehabilitation Center ( 28 , 29 )] and co-occurring tobacco use disorder (TUD) [a score of six or more on the Fagerström Test for Nicotine Dependence (FTND) measured for the past year before entering the Compulsory Drug Rehabilitation Center ( 30 , 31 )].…”

Strong chū‐hai, a Japanese ready‐to‐drink high‐alcohol‐content beverage, and hazardous alcohol use: A nationwide cross‐sectional study

“…With regard to the income indicator, we used the equivalent household income that was calculated by dividing the household income by the square root of household size (categorized by the quartiles of equivalent household income [1st quartile, JPY ≤2.49 million; 2nd quartile, JPY 2.50 to 3.25 million; 3rd quartile, JPY 3.26 to 4.75 million; 4th quartile, JPY ≥4.76 million; and unknown/declined to answer]) (Yoshioka et al, 2021). Health‐related status included smoking status (never, past, or current) (Garnett et al, 2022), psychological distress measured by the Kessler‐6 Scale (no, 0 to 4 points; moderate, 5 to 12 points; and serious, 13 to 24 points) (Furukawa et al, 2008; Verplaetse et al, 2021), and the presence of psychiatric comorbidities (depression and other psychiatric disorder(s)) (Garnett et al, 2022; Huang et al, 2020). All questionnaires and response options used in this study are described in Appendix S1.…”

“…Health-related status included smoking status (never, past, or current) (Garnett et al, 2022), psychological distress measured by the Kessler-6 Scale (no, 0 to 4 points; moderate, 5 to 12 points; and serious, 13 to 24 points) (Furukawa et al, 2008;Verplaetse et al, 2021), and the presence of psychiatric comorbidities (depression and other psychiatric disorder(s)) (Garnett et al, 2022;Huang et al, 2020). All questionnaires and response options used in this study are described in Appendix S1.…”

Effects of mindfulness-based interventions on depressive symptoms in patients with substance use disorders: a systematic review and meta-analysis

“…[1][2][3] Approximately half of the patients diagnosed with alcohol use disorder (AUD) have been co-diagnosed with depression. [4][5][6][7] The co-occurrence of SUD and major depressive disorders is associated with a greater severity and worse prognosis than either disorder alone, including a heightened risk for suicide. 1,[8][9][10] For instance, Lynch et al 9 found that SUDs were associated with increased suicide mortality; the adjusted odds ratios ranged from 2.0 (95% confidence interval [CI]: 1.7, 2.3) for patients with multiple SUDs, including a combination of alcohol (i.e., alcohol use disorder [AUD]), drug (i.e., drug use disorder [DUD]), and tobacco (i.e., tobacco use disorder [TUD]) misuse.…”