Prevalence estimates of voiding disorders in <scp>Turkish</scp> school‐age children

Kaplan, Fatih; Tabel, Yılmaz; Elmas, Ahmet Taner

doi:10.1111/luts.12358

Cited by 4 publications

(4 citation statements)

References 28 publications

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“…Selection of eligible papers were performed according to the PRISMA‐ScR document, with two independent authors for screening, full text assessment and inclusion (see Figure 1 for PRISMA 2020 selection flow diagram). Seventy‐six papers 1,10,30–103 were included. Eligible papers are summarized in Table 1, and information about candidate genes are summarized in Table 2.…”

Section: Methodsmentioning

confidence: 99%

The genetics of incontinence: A scoping review

et al. 2023

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The genetic causes underlying incontinence in both children and adults have begun to be unravelled during the last decades. The aim of this scoping review is to synthesize current knowledge on the genetics of childhood and adult urinary and faecal incontinence, identify similarities between different incontinence subgroups, and identify knowledge gaps to aid future research. PRISMA-ScR was used, and 76 studies were included. Early epidemiological family and twin studies suggest high heritability of incontinence. Linkage studies provide evidence for the existence of rare genetic variants; however, these variants have not been identified. Later candidate gene association studies and recent genome-wide association studies provide the first preliminary evidence that common risk variants also play a role. The genetics of incontinence in children and adults has predominantly been studied separately, but this review identifies for the first time the endothelin system as a potential common pathophysiological pathway. Overall, these findings strengthen the hypothesis that genetic variants play a prominent role in the pathogenesis of incontinence. Future research should include hypothesis-free studies of rare and common variants in large well-characterized cohorts with incontinence. Studies should include different age groups and ethnicities and both sexes to fully reveal the genetics of incontinence.

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Section: Methodsmentioning

confidence: 99%

The genetics of incontinence: A scoping review

et al. 2023

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“…The prevalence of Lower urinary tract symptoms (LUTS) in children has increased in recent years. Approximately one-third of children worldwide have symptoms associated with voiding problems [ 3 , 4 ]. Due to modernized lifestyle, the prevalence of LUTS in children increases because of inappropriate voiding habits and toilet training [ 4 , 5 ].…”

Section: Introductionmentioning

confidence: 99%

“…Approximately one-third of children worldwide have symptoms associated with voiding problems [ 3 , 4 ]. Due to modernized lifestyle, the prevalence of LUTS in children increases because of inappropriate voiding habits and toilet training [ 4 , 5 ]. Epidemiologically, the ratio of LUTS in school-aged children is around 2 to 20 percent, mostly urgency, intermittency, urinary incontinence and enuresis, which affect social limiting and decrease health related quality of life of the children and the parents [ 4 , 6 ].…”

Section: Introductionmentioning

confidence: 99%

Prevalence of Lower Urinary Tract Symptoms in Children with Attention-Deficit/Hyperactivity Disorder: Comparison of Hospital and Population-Based Cohorts of 13,000 Patients

Yang

Huang

Guo

et al. 2022

JCM

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This study investigates the prevalence of lower urinary tract symptoms (LUTS) in school-age children with Attention-Deficit/Hyperactivity Disorder (ADHD) based on hospital-based and population-based cohorts. Methods: The hospital-based sample comprised 42 children with ADHD and 65 without ADHD aged 6–12 years. Voiding dysfunction was assessed by the Dysfunctional Voiding Scoring System (DVSS) questionnaire. We compared the baseline data, DVSS score, and uroflowmetry between the two groups. For the population-based cohort in the national insurance database, we included 6526 children aged 6–12 years, whose claims record included the diagnosis of ADHD, and another 6526 control subjects matched by gender and age. We compared the presence of LUTS diagnosis codes between the two groups. Results: Our results showed that, for the hospital-based cohort, the mean total DVSS score and the proportion of significant LUTS in children in the ADHD group were significantly higher than in subjects in the non-ADHD group. The DVSS subscales showed that the item “I cannot wait when I have to pee” item was significantly higher in the ADHD group (1.62 ± 1.17 vs. 0.90 ± 1.09, p = 0.002). For the population-based cohort, children with ADHD had a significantly higher likelihood of storage symptoms (5.53% vs. 2.91%, p < 0.001) and enuresis (3.28% vs. 1.95%, p < 0.001) compared with those of the no ADHD group. Conclusions: Children with ADHD have a higher prevalence of significant LUTS, especially storage symptoms and enuresis, than children without ADHD. The observed correlations between ADHD and LUTS provided the supporting evidence to evaluate the concomitant voiding dysfunction in children with ADHD.

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“…Voiding dysfunction (VD) is a common problem in children with an observed rate of 9.5%-19.2% in our country. 4,5 VD may accompany with constipation. A series of pathogenesis has been suggested for the formation of VD symptoms such as pollakiuria in children with constipation.…”

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confidence: 99%