Prevalence, Incidence, and Characteristics of Tuberculosis Among Known Diabetes Patients — A Prospective Cohort Study in 10 Sites, 2013–2015

Abstract

What is already known about this topic?The association of diabetes mellitus (DM) with both increased risk of tuberculosis (TB) and unfavorable treatment outcomes has been identified by many studies (1). However, epidemic data for TB cases in DM patients is absent in China. What is added by this report?This current population-based prospective cohort study, conducted in ten counties located in eastern, central, and western China during 2013-2015, revealed a high prevalence and incidence of TB in known DM patients. Most TB cases were captured by active case-finding and a much higher presence of being asymptomatic among TB/DM patients was obtained. What are the implications for public health practice?Active case-finding should be carried out in DM patients and populations at high risk for developing TB. A TB symptom screening-based case-finding strategy is not enough; chest radiography check should be done once a year for these patients.

Undernutrition as a risk factor for tuberculosis disease

“…Six cohorts recruited participants between the 1970s and 1990s (Cegielski 2012 [ 46 ]; Dembélé 2010 [ 47 ]; Gatechompol 2022 [ 48 ]; Morán‐Mendoza 2010 [ 49 ]; Pealing 2015 [ 50 ]; Soh 2019 [ 51 ]), 28 in the 2000s (Baker 2012 [ 52 ]; Chan‐Yeung 2007 [ 53 ]; Leung 2007 [ 54 ]; Lin 2018 [ 55 ]; Maro 2010 [ 56 ]; Tiruneh 2019 [ 57 ] ‐ National Health Interview Surveys (NHIS) cohort; Benjumea‐Bedoya 2019 [ 58 ]; Chang 2015 [ 59 ]; Choun 2013 [ 60 ]; Hanrahan 2010 [ 61 ]; Kim 2018 [ 62 ]; Li 2013 [ 63 ]; Lin 2018; Liu 2015 [ 64 ]; Moore 2007 [ 65 ]; Park 2023 [ 66 ]; Van Rie 2011 [ 67 ]; Were 2009 [ 68 ]; Yen 2017 [ 69 ]; Youn 2022 [ 70 ] ‐ New Taipei City (NTC) cohort; Aibana 2016 [ 71 ]; Anaam 2020 [ 72 ]; Batista 2013 [ 73 ]; Jung 2016 [ 74 ]; Nicholas 2011 [ 75 ]; Park 2022 [ 76 ]; Sudfeld 2013 [ 77 ]; Yoo 2021a [ 78 ]), and 18 from the 2010s onwards (Ahmed 2018 [ 79 ]; Alemu 2020 [ 80 ]; Ayana 2021 [ 81 ]; Beshir 2019 [ 82 ]; Chen 2022 [ 83 ]; Cheng 2020 [ 84 , 85 ]; Cho 2022 [ 86 ]; Choi 2021 [ 87 ]; Ganesan 2023 [ 88 ]; Gedfew 2020 [ 89 , 90 ]; Getu 2022 [ …”