Prevalence, Natural History, and Outcome of Acute Fluid Collection and Pseudocyst in Children With Acute Pancreatitis

Abstract

Among children with AP, 58.6% developed AFC and 38% developed pseudocysts. Only patients with symptomatic pseudocyst need drainage, and asymptomatic pseudocyst can be safely observed irrespective of size and duration of collection.

EPC/HPSG evidence-based guidelines for the management of pediatric pancreatitis

“…In a study conducted by 7 centers, only one pediatric patient out of 380 developed necrosis 12,20,32 . Other studies found the incidence of multiple organ failure and pancreatic necrosis to be under 10% 32,106 , while the incidence of pseudocysts ranged 10-38% 32,106 . The mortality was 2-11%, mostly associated with systemic diseases 107,108 .…”

“…Complicated or symptomatic pseudocysts should be treated 112 . There are reports of successful EUS-guided drainage of pseudocysts in children 106,109 . medications, smoking, alcohol) ones also can elevate the risk of developing CP.…”

Endoscopic drainage of pancreatic fluid collections: Long‐term outcomes in children

“…[2][3][4] In spite of the growing awareness, pancreatitis is associated with considerable morbidity in children. 6 Drainage of PFC can be achieved by endoscopic, percutaneous or surgical methods. Acute fluid collections (<4 weeks old) are usually asymptomatic and most resolve spontaneously.…”

“…5 However, about 40% of pseudocysts develop symptoms requiring drainage. 6 Drainage of PFC can be achieved by endoscopic, percutaneous or surgical methods. However, endoscopic modality of drainage is associated with less morbidity and is, therefore, the initial drainage modality of choice in adult patients.…”

Endoscopic Management of Pancreatic Fluid Collections in Children

“…In a recent study, acute fluid collection developed in 58.6% of children with AP. However, pseudocyst developed in 38% and drainage was required in only 26.4% of these 10. Asymptomatic PFCs can be managed conservatively.…”