Prevalence of abnormal SPECT myocardial perfusion imaging during the COVID-19 pandemic

Hasnie, Usman; Bhambhvani, Pradeep; Iskandrian, Ami E.; Hage, Fadi G.

doi:10.1007/s00259-020-05123-z

Cited by 13 publications

(8 citation statements)

References 36 publications

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“…Hasnie et al and Nappi et al have hypothesized that the percentage of abnormal myocardial perfusion images would increase in the pandemic period, because those who have mild symptoms and a probably normal SPECT MPI would delay their examinations. However, no such signi cant increase was observed [3,21].…”

Section: Discussionmentioning

confidence: 81%

Myocardial Perfusion Spect Findings In Postcovid Period

Araz

Soydal

Sütçü

et al. 2021

Preprint

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Purpose: To investigate if i) the risk of ischemia on Myocardial Perfusion Scan (MPS) ii) number of coronary angiographies (CAG) performed iii) necessity for invasive (stent implantation or coronary artery by-pass grefting (CABG)) or medical treatment increased in patients infected with COVID-19.Methods:Patients who were referred to MPS between August 2020-April 2021 with a history of active symptomatic Covid-19 infection (confirmed by PCR positivity) in the last 6 months were involved in the study group. Age-and gender matched control group was composed of randomly chosen patients who attended for MPS between January 2019 – September 2019, before pandemic. Frequency of ischemia, CAG, invasive or medical treatments were compared between groups. Results:Ischemia was reported more frequently in the study group (p<0.001). In clinical evaluation, regardless of the MPS results, the necessity for invasive evaluation with CAG and treatment (either medical therapy or invasive interventions), was higher in the study group (p=0.006 and p=0.015). It was also true for patients with abnormal MPS results (p=0.008 and p=0.024) but not for the patients with ischemia (p=0.29 and p=0.06).Conclusion:There exists a significant increase in the frequency of ischemia on MPS, undergoing CAG, stent implantation or CABG and initiation of medical therapy in patients with a history of Covid-19 infection in the last 6 months. MPS is a reliable method in patients who present with cardiovascular symptoms in the late COVID period.

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Section: Discussionmentioning

confidence: 81%

Myocardial Perfusion Spect Findings In Postcovid Period

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et al. 2021

Preprint

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“…Hasnie et al at the University of Alabama Medical Center in Birmingham, USA, compared the mean number of MPIs performed in 2020 with the mean number performed in 2019, which revealed an 81% decrease [ 37 ]. The number of abnormal SPECT MPIs was 31% in 2020 and 27% in 2019.…”

Section: Resultsmentioning

confidence: 99%

Myocardial perfusion imaging in the era of COVID-19: a systematic review

Hassanzadeh

Neshat

Heidari

et al. 2022

Clin Transl Imaging

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Purpose As COVID-19 was uncovered, it became evident that specific individuals could experience multi-organ complications for quite a while after infection. Among them, there were several cardiovascular complications. Myocardial perfusion imaging single photon emission computed tomography (MPI SPECT) can be utilized to detect and evaluate cardiac problems regardless of whether COVID caused them. By examining all publications relevant to the impacts of the pandemic on SPECT MPI imaging, we aimed to understand how the COVID pandemic affected different aspects of the MPI, how intense these effects were, and what the consequences were. Method On the 6th of June, 2022, a four-domain search strategy was developed and implemented by searching the following databases: PubMed, SCOPUS, EMBASE, Web of Science, and the Cochrane Central Register of Controlled Trials. The retrieved records have been put through two levels of screening. The search for forward and backward citations provided more results. Results This study contained 32 papers, divided into the following three categories: 1. Case reports and series; 2. A comparison of the number of MPIs conducted before and after the pandemic; and 3. SPECT MPI findings. Conclusion We observed through the article review that CT scans performed in combination with MPI are crucial and should be interpreted within the context of COVID, especially during outbreaks. Moreover, we discovered that in the initial months of the pandemic, the number of SPECT MPIs performed globally decreased, with the fall being more significant in some countries, primarily in low- to middle-income regions. Lastly, we found that individuals with a history of COVID-19 may be more prone to having MPIs that demonstrate abnormalities, such as ischemia. Graphical abstract

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Section: Discussionmentioning

confidence: 99%

Myocardial perfusion SPECT findings in postCOVID period

Araz

Soydal

Sütçü

et al. 2021

Eur J Nucl Med Mol Imaging

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Purpose To investigate if (i) the risk of ischemia on myocardial perfusion scan (MPS), (ii) number of coronary angiographies (CAG) performed, and (iii) necessity for invasive (stent implantation or coronary artery bypass grafting (CABG)) or medical treatment increased in patients infected with COVID-19. Methods Patients who were referred to MPS between August 2020 and April 2021 with a history of active symptomatic COVID-19 infection (confirmed by PCR positivity) in the last 6 months were involved in the study group. Age-and gender-matched control group was composed of randomly chosen patients who attended for MPS between January 2019 and September 2019, before pandemic. Frequency of ischemia, CAG, and invasive or medical treatments were compared between groups. Results Ischemia was reported more frequently in the study group ( p < 0.001). In clinical evaluation, regardless of the MPS results, the necessity for invasive evaluation with CAG and treatment (either medical therapy or invasive interventions) was higher in the study group ( p = 0.006 and p = 0.015). It was also true for patients with abnormal MPS results ( p = 0.008 and p = 0.024) but not for the patients with ischemia ( p = 0.29 and p = 0.06). Conclusion There exists a significant increase in the frequency of ischemia on MPS, undergoing CAG, stent implantation or CABG, and initiation of medical therapy in patients with a history of COVID-19 infection in the last 6 months. MPS is a reliable method in patients who present with cardiovascular symptoms in the late COVID period.

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Prevalence of abnormal SPECT myocardial perfusion imaging during the COVID-19 pandemic

Cited by 13 publications

References 36 publications

Myocardial Perfusion Spect Findings In Postcovid Period

Myocardial Perfusion Spect Findings In Postcovid Period

Myocardial perfusion imaging in the era of COVID-19: a systematic review

Myocardial perfusion SPECT findings in postCOVID period

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