Prevalence of acute toxoplasmosis infection among 41,112 pregnant women and the mother-to-child transmission rate in a public hospital in South Brazil

Varella, Ivana Rosângela dos Santos; Canti, Ivete Cristina Teixeira; Santos, Breno; Coppini, Angela Z; Argondizzo, Luciana C; Tonin, Carina; Wagner, Mário Bernardes

doi:10.1590/s0074-02762009000200037

Cited by 50 publications

(38 citation statements)

References 38 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…These results are in agreement with another study among pregnant women in Makkah, Saudi Arabia which revealed that only around 10% of the participants were aware of the toxoplasmosis [24]. In Brazil, studies presented that only 35% of included pregnant women knew about this disease [29]. 77.3% of the aware participants have studied in scientific colleges which indicate that education represents one of the major sources of the information about toxoplasmosis.…”

Section: Discussionsupporting

confidence: 88%

Toxoplasmosis among Saudi Female Students in Al-Ahssa, Kingdom of Saudi Arabia: Awareness and Risk Factors

AlRashada¹,

Al-Gharrash²,

Alshehri³

et al. 2016

OJPM

View full text Add to dashboard Cite

Background: Toxoplasmosis is a worldwide disease that severely affects the fetuses and immunocompromised patients and results in many critical and life threatening conditions. The present study aimed to evaluate the awareness of toxoplasmosis and its preventive behaviors among female students in King Faisal University in Al-Ahssa. Subjects and methods: A cross sectional study was conducted in April 2014 among female students in KFU. The data were collected by a questionnaire from 88 participants. Results: Results showed that 65.4% were not aware of toxoplasmosis, and only 28.2% were aware of its complications or risk factors. This study showed that some people are at risk to get toxoplasmosis as they do not wash their hands with water and soap before eating (48.8%), do not wash the fruits and vegetables with water and soap (78.2%), drink tank water (51.3%) and cat owners don't follow the proper measures for their cats. However, some people practice some of the preventive behaviors as they do not raise the cats (93.6%) and do not consume unpasteurized or unboiled milk (100%) or undercooked meat (92.3%). Conclusion: The current study proved the low awareness of toxoplasmosis which emphasized the need to educate the people in Al-Ahssa about the preventive methods, especially the pregnant women to prevent the severe complications of congenital infections.

show abstract

Section: Discussionsupporting

confidence: 88%

Toxoplasmosis among Saudi Female Students in Al-Ahssa, Kingdom of Saudi Arabia: Awareness and Risk Factors

AlRashada¹,

Al-Gharrash²,

Alshehri³

et al. 2016

OJPM

View full text Add to dashboard Cite

show abstract

“…It may lead severe CNS impairment, which might not manifest for several years. Infection in children without evidence of exposure to T. gondii has been recorded (Varella et al, 2009). Domestic cats are the definite host of T.gondii.…”

Section: *Corresponding Author: Tel: +234-8035374004; E-mail: Wellao@mentioning

confidence: 99%

Congenital Toxoplasmosis: A Review of its Pathology, Immune Response and Current Treatment Options.

Wellington¹,

Oladipo²,

Chimere

et al. 2010

Sierra Leone j. biomed. res.

View full text Add to dashboard Cite

Toxoplasmosis, caused by the protozoan parasite Toxoplasma gondii, is one of the most common parasites of man and other warm-blooded animals. Humans are infected through contaminated food, water, and blood transfusion, organ transplantation or from mother to foetus through the placenta. Severe congenital infections occur as a result of primary T. gondii infection in early pregnancy. Transmission of T.gondii to the foetus can result in serious health problems, including mental retardation, seizures, blindness and death. Frequency of foetal infection is higher when maternal infection occurs later in pregnancy and sequelae are more severe when maternal infections occur early in the first trimester of pregnancy. The ability of the parasite to survive intracellularly largely depends on the blocking of different proapoptotic signaling cascades of the host cells. During pregnancy, however, alterations in the incidence of apoptosis are associated with abnormal placental morphology and function. Both cellular and humoral immune responses control T.gondii infection. Toxoplasma is asymptomatic, infected women can only be detected by serological testing. In many instances, congenital toxoplasmosis can be prevented by educating pregnant women and women of childbearing age about the route of transmission. The need for screening suspected cases of T. gondii will help reduce transmission to the foetus.

show abstract

“…Studies have found a prevalence of congenital toxoplasmosis between 0.6-1.3/1000 live births in different regions of Brazil [4][5][6] . It has been suggested that the chance of transmission of toxoplasmosis from mother to fetus ranges from 18.5 to 23% 6,7 .…”

Section: Introductionmentioning

confidence: 99%

“…It has been suggested that the chance of transmission of toxoplasmosis from mother to fetus ranges from 18.5 to 23% 6,7 . The risk of fetal infection is less than 15% in the first trimester, but in general, the disease is severe in the newborn.…”

Section: Introductionmentioning

confidence: 99%

Alterações auditivas em crianças expostas à toxoplasmose durante a gestação

et al. 2017

View full text Add to dashboard Cite

RESUMO Objetivo: verificar a ocorrência e o tipo mais frequente de alteração auditiva em crianças expostas a toxoplasmose durante a gestação. Métodos: estudo retrospectivo longitudinal realizado em instituição pública de saúde de São Paulo. Análise de prontuários de crianças nascidas entre 2010 e 2015 distribuídos em dois grupos: grupo estudo, composto por 48 crianças de mães com diagnóstico de toxoplasmose durante a gestação; e grupo controle, composto por 43 crianças sem infecção congênita que foram acompanhadas por apresentar baixo peso ao nascimento. As crianças foram avaliadas de duas a quatro vezes durante os dois primeiros anos de vida, por meio de testes que avaliam a função auditiva periférica e central. Resultados: 47 crianças fizeram apenas duas avaliações e apenas 11 completaram todas as avaliações até 24 meses. No grupo controle 58,1% apresentaram audição normal, 37,2% perda condutiva, 4,7% perda coclear e ausência de alteração retrococlear, enquanto o grupo estudo apresentou 56,3% de audição normal, 20,8% de perda condutiva, 2,1% de perda coclear e 20,8% de alteração retrococlear. Conclusão: crianças expostas à toxoplasmose durante a gestação não diferiram das não expostas em relação à ocorrência de perda auditiva coclear e condutiva. Entretanto, apresentaram maior ocorrência de alteração retrococlear.

show abstract

Prevalence of acute toxoplasmosis infection among 41,112 pregnant women and the mother-to-child transmission rate in a public hospital in South Brazil

Cited by 50 publications

References 38 publications

Toxoplasmosis among Saudi Female Students in Al-Ahssa, Kingdom of Saudi Arabia: Awareness and Risk Factors

Toxoplasmosis among Saudi Female Students in Al-Ahssa, Kingdom of Saudi Arabia: Awareness and Risk Factors

Congenital Toxoplasmosis: A Review of its Pathology, Immune Response and Current Treatment Options.

Alterações auditivas em crianças expostas à toxoplasmose durante a gestação

Contact Info

Product

Resources

About