Prevalence of alcohol use disorder among individuals who binge eat: a systematic review and meta‐analysis

Bogusz, Krzysztof; Kopera, Maciej; Trucco, Elisa M.; Kucharska, Katarzyna; Walenda, Anna; Wojnar, Marcin

doi:10.1111/add.15155

Cited by 26 publications

(20 citation statements)

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“…Epidemiological studies have revealed a high comorbidity between AUD and overeating pathologies such as obesity and binge-eating disorder (BED) [ 39 ]. Many obese and BED patients have difficulties restraining from consuming palatable foods (high in fat, sugar and/or salt content) and engage in compulsive behaviors similar to those observed in substance abuse disorder [ 40 , 41 ].…”

Section: Introductionmentioning

confidence: 99%

Pairing Binge Drinking and a High-Fat Diet in Adolescence Modulates the Inflammatory Effects of Subsequent Alcohol Consumption in Mice

González-Portilla

Montagud‐Romero

Navarrete

et al. 2021

IJMS

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Alcohol binge drinking (BD) and poor nutritional habits are two frequent behaviors among many adolescents that alter gut microbiota in a pro-inflammatory direction. Dysbiotic changes in the gut microbiome are observed after alcohol and high-fat diet (HFD) consumption, even before obesity onset. In this study, we investigate the neuroinflammatory response of adolescent BD when combined with a continuous or intermittent HFD and its effects on adult ethanol consumption by using a self-administration (SA) paradigm in mice. The inflammatory biomarkers IL-6 and CX3CL1 were measured in the striatum 24 h after BD, 3 weeks later and after the ethanol (EtOH) SA. Adolescent BD increased alcohol consumption in the oral SA and caused a greater motivation to seek the substance. Likewise, mice with intermittent access to HFD exhibited higher EtOH consumption, while the opposite effect was found in mice with continuous HFD access. Biochemical analyses showed that after BD and three weeks later, striatal levels of IL-6 and CX3CL1 were increased. In addition, in saline-treated mice, CX3CL1 was increased after continuous access to HFD. After oral SA procedure, striatal IL-6 was increased only in animals exposed to BD and HFD. In addition, striatal CX3CL1 levels were increased in all BD- and HFD-exposed groups. Overall, our findings show that adolescent BD and intermittent HFD increase adult alcohol intake and point to neuroinflammation as an important mechanism modulating this interaction.

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Section: Introductionmentioning

confidence: 99%

Pairing Binge Drinking and a High-Fat Diet in Adolescence Modulates the Inflammatory Effects of Subsequent Alcohol Consumption in Mice

González-Portilla

Montagud‐Romero

Navarrete

et al. 2021

IJMS

View full text Add to dashboard Cite

show abstract

“…Less is known clinically, however, about the potential for HFD consumption to increase EtOH intake. Cross-sectional studies report that binge eating behaviors, which can be associated with increased propensity for obesity, are not only associated with increased intake of food higher in energy density, but also increased consumption of EtOH (Muñoz-Pareja et al, 2013 ; Bogusz et al, 2021 ). There are many shared mechanisms between binge eating disorders and drug addiction, including alterations in reward signaling and emotional processing (Carlier et al, 2015 ; Schulte et al, 2016 ; Moore et al, 2017a , b ), which suggests that binging may be part of an overall compulsive behavioral phenotype that can straddle reward modalities.…”

Section: Potential Central Mechanisms Of High Fat Diet and Alcohol Bementioning

confidence: 99%

Impact of High Fat Diet and Ethanol Consumption on Neurocircuitry Regulating Emotional Processing and Metabolic Function

Coker

Keller

Arnold

et al. 2021

Front. Behav. Neurosci.

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The prevalence of psychiatry disorders such as anxiety and depression has steadily increased in recent years in the United States. This increased risk for anxiety and depression is associated with excess weight gain, which is often due to over-consumption of western diets that are typically high in fat, as well as with binge eating disorders, which often overlap with overweight and obesity outcomes. This finding suggests that diet, particularly diets high in fat, may have important consequences on the neurocircuitry regulating emotional processing as well as metabolic functions. Depression and anxiety disorders are also often comorbid with alcohol and substance use disorders. It is well-characterized that many of the neurocircuits that become dysregulated by overconsumption of high fat foods are also involved in drug and alcohol use disorders, suggesting overlapping central dysfunction may be involved. Emerging preclinical data suggest that high fat diets may be an important contributor to increased susceptibility of binge drug and ethanol intake in animal models, suggesting diet could be an important aspect in the etiology of substance use disorders. Neuroinflammation in pivotal brain regions modulating metabolic function, food intake, and binge-like behaviors, such as the hypothalamus, mesolimbic dopamine circuits, and amygdala, may be a critical link between diet, ethanol, metabolic dysfunction, and neuropsychiatric conditions. This brief review will provide an overview of behavioral and physiological changes elicited by both diets high in fat and ethanol consumption, as well as some of their potential effects on neurocircuitry regulating emotional processing and metabolic function.

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“…Many previous studies have linked trait impulsivity to binge eating behaviors in clinical patients with BED ( 20 , 21 ). Nevertheless, these samples always had high comorbidity with attention-deficit/hyperactivity disorder (ADHD) ( 22 ), anxiety disorders ( 23 ), and substance use disorders ( 24 ), which might lead to confounding results when detecting the relationship between impulsivity and BED. Moreover, limited data on the associations of trait impulsivity and BED have been incongruous among general populations.…”

Section: Introductionmentioning

confidence: 99%

Trait Impulsivity and Choice Impulsivity in Young Adult Students With Probable Binge Eating Disorder

2022

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BackgroundBinge eating disorder (BED) as a public health problem has been included in the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5). Akin to addictive disorders, impulsivity-related neuropsychological constructs might be potentially involved in the onset and development of BED. However, it remains unclear which facets of impulsivity are connected to overeating and binge eating behaviors among non-clinical populations. The present study aimed to detect the relationship between impulsivity and binge eating both on the personality-trait and behavioral-choice levels in undiagnosed young adults.MethodsFifty-eight individuals with probable BED and 59 healthy controls, matched on age, gender, and educational level, were assessed by using a series of self-report measurements, including the Barratt Impulsiveness Scale (BIS-11), UPPS-P Impulsive Behaviors Scale (UPPS-P), Delay Discounting Test (DDT), and Probability Discounting Test (PDT).ResultsMultivariate analysis of variance models revealed that compared with healthy controls, the probable BED group showed elevated scores on the BIS-11 Attentional and Motor impulsiveness, and on the UPPS-P Negative Urgency, Positive Urgency, and Lack of Perseverance. However, the probable BED subjects had similar discounting rates on the DDT and PDT with healthy controls. Regression models found that Negative Urgency was the only positive predictor of binge eating behavior.ConclusionsThese findings suggested that typical facets of trait impulsivity, which have been recognized in addictive disorders, were associated with binge eating in young adults, whereas choice impulsivity was not aberrantly seen in the same probable BED sample. This study might promote a better understanding of the pathogenesis of BED.

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Prevalence of alcohol use disorder among individuals who binge eat: a systematic review and meta‐analysis

Cited by 26 publications

References 70 publications

Pairing Binge Drinking and a High-Fat Diet in Adolescence Modulates the Inflammatory Effects of Subsequent Alcohol Consumption in Mice

Pairing Binge Drinking and a High-Fat Diet in Adolescence Modulates the Inflammatory Effects of Subsequent Alcohol Consumption in Mice

Impact of High Fat Diet and Ethanol Consumption on Neurocircuitry Regulating Emotional Processing and Metabolic Function

Trait Impulsivity and Choice Impulsivity in Young Adult Students With Probable Binge Eating Disorder

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