ric Ophthalmology and Strabismus (AAPOS) published a set of risk factors for amblyopia. The intent was to promote uniformity of reporting and development in screening. Because this prevalence is not yet known, this meta-analysis is an attempt to estimate it.Methods: Major community preschool eye examination studies were reviewed and AAPOS cut-off s estimated.
Results:The approximate prevalence of anisometropia is 1.2%, hyperopia is 6%, astigmatism is 15%, myopia is 0.6%, strabismus is 2.5%, and visual acuity less than 20/40 is 6%. The mean combined prevalence is 21% ± 2% compared to a prevalence of amblyopia 20/40 and worse of 2.5%.
Conclusions:Knowing risk factor prevalence simplifi es validation eff orts. Amblyopia screening with a risk factor sensitivity less than 100% is expected and desirable.
214Copyright © SLACK Incorporated comprehensive eye examination to be able to estimate sensitivity and specifi city.
PATIENTS AND METHODSMajor pediatric comprehensive eye examination studies were reviewed from publications and from author communication.6 Data from children between the ages of 2 and 5 years were collected. Specifi c risk factor prevalence profi les were determined. The type of regression curve that best fi t the study with the most data points (Ottar et al. 4 ) was a power curve. Unavailable data were then interpolated/extrapolated. Interactions and coexisting risk factors were extracted from data from Ottar et al. 4 and Matta et al. 6 and sorted by amblyopia propensity.