Prevalence of and Factors Associated With Helicobacter Pylori Infection in Children in the North of Vietnam

Abstract

Abstract. The study aimed at evaluating the seroprevalence of and sociodemographic, health, lifestyle, and environmental hygiene conditions associated with Helicobacter pylori infection in Vietnamese children. Data from 824 children, aged from 6 months to 15 years and gastrointestinal symptom free when consulted, admitted to a university hospital, were collected using a structured questionnaire and ELISA test for H. pylori infection. The data were examined using univariate and multivariate analyses. H. pylori seroprevalence was 34.0%. Age groups from 3 to 6 years and older than 6, and number of offspring were positively and independently associated with H. pylori seropositivity [adjusted OR (95% CI): 2.9 (1.5-5.5); 1.9 (1.1-3.1) and 1.8 (1.1-2.6), respectively]. Breastfeeding more than 6 months was negatively and independently associated with H. pylori seropositivity [adjusted OR (95% CI): 0.5 (0.3-0.9)]. Mother's age, history of allergy, gastro-duodenal disease history in the past, initiating collective life before 6 years, sharing bed with parents and time of bed sharing with parents > 24 months were positively but not independently associated with H. pylori seropositivity. None of the other environmental or lifestyle conditions examined was associated with H. pylori infection. Our results support person-to-person transmission and the role of sociodemographic factors in H. pylori infection.

Association Between HLA-DQ Genotypes and Haplotypes vs Helicobacter pylori Infection in an Indonesian Population

“…In Asia, infection rates of H. pylori are high in Japan , Korea (Lee et al, 2008), China (Brown et al, 2002) and Vietnam (Nguyen et al, 2006) and the incidence rates of gastric cancer are generally high in the areas with a higher prevalence of H. pylori infection. In Indonesia, on the other hand, not only urea breath testing (UBT) but also IgG antibodies to H. pylori were found to be low in men and women, significantly lower than the 62% and 57%, respectively, in Japan.…”

Prevalence and Risk Factors of Helicobacter pylori Infection in Muong Children in Vietnam

“…High rates of H. pylori infection were reported in both hospital-based and community-based studies from Vietnam [10][11][12][13]. Different risk factors for H. pylori infection have been identified in the Kinh ethnic majority [10][11][12] and among ethnic minorities [13][14][15]. As the socioeconomic level and the lifestyle vary considerably among ethnic groups in the country, the prevalence of H. pylori infection and particularly the risk factors for this infection differed in previous studies [10][11][12][13][14][15].…”

“…We used a structured questionnaire, as in previous studies [12][13][14] for data collection on sociodemographic, health status and potential exposure. The information was collected from the head of the households while the study investigators completed the questionnaires.…”

“…Vietnam is also home to 54 ethnic groups with different cultures, of which 75% to 80% are living in rural or remote areas [8,9]. High rates of H. pylori infection were reported in both hospital-based and community-based studies from Vietnam [10][11][12][13]. Different risk factors for H. pylori infection have been identified in the Kinh ethnic majority [10][11][12] and among ethnic minorities [13][14][15].…”

“…Different risk factors for H. pylori infection have been identified in the Kinh ethnic majority [10][11][12] and among ethnic minorities [13][14][15]. As the socioeconomic level and the lifestyle vary considerably among ethnic groups in the country, the prevalence of H. pylori infection and particularly the risk factors for this infection differed in previous studies [10][11][12][13][14][15]. According to the General Statistics Office of the Government of Vietnam 2009 [9], the Muong is the thirst largest ethnic group in Vietnam after the majority Kinh and Tay ethnic groups with an estimated more than one million people.…”