Prevalence of and risk factors for Helicobacter pylori infection among healthcare workers at a teaching hospital in Rome: the Catholic University Epidemiological Study

Gasbarrini, Antonio; Anti, M.; Franceschi, Francesco; Armuzzi, Alessandro; Cotichini, Rodolfo; Ojetti, Veronica; Candelli, Marcello; Lippi, M; Paolucci, M.; Cicconi, Valerio; Cammarota, Giovanni; Danese, Silvio; Silveri, Nicolò Gentiloni; Catananti, Cesare; Pola, Paolo; Stroffolini, Tommaso; Gasbarrini, Giovanni

doi:10.1097/00042737-200102000-00015

Cited by 13 publications

(24 citation statements)

References 23 publications

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“…An appearance for a gastro oral route has also designed some studies of transmission. 19 There are various studies been carried out mainly, genetic predilection to infection, alcohol and tobacco use, ABO blood type and dietary &nutritional influences which were the role played by other reasons and its results have been illogical. 16 A comprehensive pervasive of infection of almost 40% which was surprisingly a latter survey of 655 topics from a teaching hospital in Rome with an increased pervasiveness among nurses and complementary apprentices than among the physicians.…”

Section: Epidemiologymentioning

confidence: 99%

“…19 Once in the presence of the gastric mucosa, bacteria induce a transient hypochlorhydria by an unknown mechanism. 13 The urease enzyme produced by the bacteria alters the microenvironment of the organism to facilitate colonization.…”

Section: Figure 1 Photomicrograph Of Helicobacter Pylorimentioning

confidence: 99%

“…Second, only those patients in whom treatment will make a difference should be tested. 19 Definite evidence does not exist that eradication of the infection in patients with simple dyspepsia will relieve symptoms and testing of asymptomatic patients without a history of documented peptic ulcer disease is not warranted. Testing can be considered on a case by case basis in patients with symptoms suggestive of peptic ulcer disease.…”

Section: General Diagnostic Principlesmentioning

confidence: 99%

“…19 Moreover, many of the recommended regimens are difficult for patients to take, leading to problems with compliance; specifically, having to take a large number of pills at least twice daily and coping with unpleasant adverse effects do little to encourage patient cooperation. Despite these obstacles, current regimens can obtain cure rates in excess of 85% in most patient populations.…”

Section: General Treatment Principlesmentioning

confidence: 99%

“…Omeprazole mixture has been assured as an active agent through Nitazoxanide. 19 And additional surveillance is continuing. In accumulation, the clarithromycin might show a character of imminent therapies except macrolides.…”

Section: Antibiotics and Other Agentsmentioning

confidence: 99%

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A clinical review on the pathology and management "Helicobacter pylori" infection.

2016

Int. J. Adv. Res. Biol. Sci.

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Abstract"Helicobacter pylori" have now been established as one of the sources of acute and chronic gastritis, duodenitis, gastric peptic ulcers and duodenal ulcers non-ulcer dyspepsia and Weird diseases and syndromes. It has been identified as a risk factor for gastric cancer and MALT-lymphoma. More than 90% of patients with duodenal ulcers and more than 70% of those with gastric ulcer and more than 80% patients with the gastric cancer have "" infection. Diagnosis of "" could be meddlesome like endoscopy and non-interfering such as urea-breath-test, detection of antigens in stool, detection of specific antibodies in patients' sera by means of serological tests--ELISA and Immunblott, molecular tests PCR and fluorescence-in situ-hybridization which also checks its resistance against clarithromycin and metronidazole. The treatment is still a challenge. There are many determinants for successful therapy like individual primary or secondary antibiotics resistance, mucosal drug concentration, patient compliance, side-effect profile and cost. Latest therapy relies on different mixtures of known antibiotics and anti-secretory agents. In a few studies, a standard triple therapy consisting of two antibiotics and a proton-pump inhibitor has been proposed as the first-line regimen. Bismuth-containing quadruple treatment, sequential treatment or a non-bismuth quadruple treatment (concomitant) are also an alternative therapy. Levofloxacin containing triple treatment are recommended as rescue treatment for infection of "" after defeat of first-line therapy. Achieving a successful "H. pylori" vaccine is a feasible route towards treatment which will have synergistic or additive consequence against "H. pylori".

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Section: Epidemiologymentioning

confidence: 99%

Section: Figure 1 Photomicrograph Of Helicobacter Pylorimentioning

confidence: 99%

Section: General Diagnostic Principlesmentioning

confidence: 99%

Section: General Treatment Principlesmentioning

confidence: 99%

Section: Antibiotics and Other Agentsmentioning

confidence: 99%

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A clinical review on the pathology and management "Helicobacter pylori" infection.

2016

Int. J. Adv. Res. Biol. Sci.

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The occupational risk of Helicobacter pylori infection: a systematic review

Kheyre

Morais

Ferro

et al. 2018

Int Arch Occup Environ Health

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Our results show an occupational risk of H. pylori infection supporting the role of oral-oral, fecal-oral, and zoonotic transmission. Studies comparing specific occupational groups with adequate comparators may contribute to better identify groups at higher risk of infection. The recognition of this infection as an occupational disease would result in early detection and treatment, as well as prevention and control of its transmission in workplaces.

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Helicobacter pylori infection in hospital workers over a 5-year period: correlation with demographic and clinical parameters

Triantafillidis

Gikas

Hyphantis

et al. 2002

Journal of Gastroenterology

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In this longitudinal study of workers in a large acute care hospital in Greece it was found that nursing staff had a significantly higher risk of infection compared with administrative and technical staff. Age was significantly positively related both to H. pylori infection and to seroconversion. The level of education was strongly related to the prevalence, but not to the incidence of H. pylori infection. The presence of infection over the time was associated with a higher percentage of heartburn, regurgitation, and nausea compared with subjects who were continuously negative for H. pylori infection.

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Prevalence of and risk factors for Helicobacter pylori infection among healthcare workers at a teaching hospital in Rome: the Catholic University Epidemiological Study

Cited by 13 publications

References 23 publications

A clinical review on the pathology and management "Helicobacter pylori" infection.

A clinical review on the pathology and management "Helicobacter pylori" infection.

The occupational risk of Helicobacter pylori infection: a systematic review

Helicobacter pylori infection in hospital workers over a 5-year period: correlation with demographic and clinical parameters

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